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Established Cell Lines as Tools in the Study of Human Lymphoma and Myeloma Cell Characteristics

  • Conference paper
Immunological Diagnosis of Leukemias and Lymphomas

Part of the book series: Haematology and Blood Transfusion / Hämatologie und Bluttransfusion ((HAEMATOLOGY,volume 20))

Abstract

Recent advances in immunology and cell biology have indicated that the diagnosis of a hematopoietic malignancy in many instances should not be based solely on classical morphology. For instance, it has been demonstrated that lymphocyte subpopulations, although morphologically indistinguishable, may have quite different functional properties and obviously represent different stages of lymphoid differentiation. Tumors may evolve from any of these morphologically identical cell types. The position in the differentiation lineage of a malignant cell can be expected to be followed by a unique in vivo behavior, e.g. with respect to growth rate and tendency to metastasize. For therapeutic and prognostic reasons it is therefore essential to delineate the origin of the tumor cell clone by non-morphological methods.

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Authors and Affiliations

  1. The Wallenberg Laboratory, University of Uppsala, Uppsala, Sweden

    K. Nilsson

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  1. K. Nilsson
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  1. Institut für Hämatologie der Gesellschaft für Strahlen- und Umweltforschung, Landwehrstraße 61, D-8000, München 2, Bundesrepublik Deutschland

    Stefan Thierfelder , Hans Rodt  & Eckhard Thiel ,  & 

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Nilsson, K. (1977). Established Cell Lines as Tools in the Study of Human Lymphoma and Myeloma Cell Characteristics. In: Thierfelder, S., Rodt, H., Thiel, E. (eds) Immunological Diagnosis of Leukemias and Lymphomas. Haematology and Blood Transfusion / Hämatologie und Bluttransfusion, vol 20. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-66639-1_31

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  • DOI: https://doi.org/10.1007/978-3-642-66639-1_31

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-08216-3

  • Online ISBN: 978-3-642-66639-1

  • eBook Packages: Springer Book Archive

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