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Phytoecdysones and Protein Metabolism in Mammalia

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Invertebrate Endocrinology and Hormonal Heterophylly

Abstract

It has become generally recognized that metamorphosing hormones of insects are distributed widely in the plant kingdom, and isolation and chemical characterization of several kinds of these substances, the phytoecdysones, have been reported (Hikino et al., 1970). Since these phytoecdysones have a steroidal skeleton such as that of adrenal corticoids, sex hormones, etc. and since the plants containing these steroids are generally used in oriental medicine and are dietary sources for mammals, it seemed of interest to investigate the effect of these steroids on mammalian metabolic systems.

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References

  1. Burdette, W. J. and Coda, R. C.: Effect of Ecdysone on Incorporation of C14 — Leucine into Hepatic Protein in Vitro. Proc. Soc. Exptl. Biol. Med., 112:216, 1963.

    CAS  Google Scholar 

  2. Burdette, W. J.: The Significance of Invertebrate Hormones in Relation to Differentiation. Cancer Research, 24:521–536, 1964.

    PubMed  CAS  Google Scholar 

  3. Goldberg, L. H. and Rabinowitz, M.: Actinomycin-D Inhibition of Deoxyribonucleic Acid-dependent Synthesis of Ribonucleic Acid. Science, 136:315–316, 1962.

    Article  PubMed  CAS  Google Scholar 

  4. Goodman, H. M. and Rich, A.: Mechanism of Polyribosome Action During Protein Synthesis. Nature, 199:318–322, 1963.

    Article  PubMed  CAS  Google Scholar 

  5. Gornall, A. G., Bardawill, C. J., and Herman, M.: Determination of Serum Proteins by Means of Biuret Reaction. J. Biol. Chem., 177:751–766, 1949.

    PubMed  CAS  Google Scholar 

  6. Franklin, R. M.: The Inhibition of Ribonucleic Acid Synthesis in Mammalian Cells by Actinomycin D. Biochem. Biophys. Acta, 72:555–565, 1963.

    Article  PubMed  CAS  Google Scholar 

  7. Hadjivassiliou, A. and Brawerman, G.: Template and Ribosomal Ribonucleic Acid Components in the Nucleus and the Cytoplasm of Rat Liver. Biochemistry, 6:1934, 1967.

    Article  PubMed  CAS  Google Scholar 

  8. Hiatt, H. H.: A Rapidly Labeled RNA in Rat Liver Nuclei. J. Mol. Biol., 5:217–229, 1962.

    Article  PubMed  CAS  Google Scholar 

  9. Hikino, H. and Hikino, Y.: Arthropod Molting Hormones. Fortschr. Chem. Org. Naturstoffe, 28:256, 1970.

    CAS  Google Scholar 

  10. Hikino, H., Nabetani, S., Nomoto, K., Arai, T., Takemoto, T., Otaka, T., and Uchiyama, M.: Effect of Long Term Administration of Insect-metamorphosing Substances on Higher Animals. Yakugaku Zasshi, 89:235, 1969.

    PubMed  CAS  Google Scholar 

  11. Koike, K., Otaka, T., and Okui, S.: Regulation of Protein Synthesis in Mouse Liver by Steroid Hormones. J. Biochem. (Tokyo), 61:619, 1967.

    Google Scholar 

  12. Koike, K., Otaka, T., and Okui, S.: Induction of Heme-protein Enzyme in Animal Cells IV. Relationship Between Rapidly Labeled RNA and Induced Synthesis of Tryptophan Oxygenase in Vivo. J. Biochem. (Tokyo), 59:201, 1966.

    CAS  Google Scholar 

  13. Lukács, I. and Sekeris, C. E.: On the Mechanism of Human Action IX. Stimulation of RNA Polymerase Activity of Rat Liver Nuclei by Cortisol in Vitro. Biochim. Biophys. Acta, 134:85, 1967.

    Google Scholar 

  14. Meritz, I.: Actinomycin Inhibition of RNA Synthesis in Rat Liver. Biochem. Biophys. Res. Commun., 10:254, 1963.

    Google Scholar 

  15. Munro, A. J. and Korner, A.: Determination of a Rapidly Labeled Ribonucleic Acid in the Cytoplasm of Rat Liver. Biochem. J., 85:37P, 1962.

    Google Scholar 

  16. Noll, H., Staehelin, T., and Wettstein, F. O.: Ribosomal Aggregates Engaged in Protein Synthesis; Ergosome Breakdown and Messenger Ribonucleic Acid Transport. Nature, 198:632–638, 1963.

    Article  Google Scholar 

  17. Okui, S., Otaka, T., Uchiyama, M., Takemoto, T., Hikino, H., Ogawa, S., and Nishimoto, N.: Stimulation of Protein Synthesis in Mouse Liver by Insectmoulting Steroids. Chem. Pharm. Bull., 16:384, 1968.

    PubMed  CAS  Google Scholar 

  18. Otaka, T., Okui, S., and Uchiyama, M.: Stimulation of Protein Synthesis in Mouse Liver by Ecdysterone. Chem. Pharm. Bull., 17:15, 1969.

    Google Scholar 

  19. Otaka, T. and Uchiyama, M.: Stimulatory Effect of Ecdysterone on RNA Synthesis in Mouse Liver. Chem. Pharm. Bull., 17:1883, 1969.

    PubMed  CAS  Google Scholar 

  20. Otaka, T. and Uchiyama, M.: Stimulatory Effect of Insect-metamorphosing Steroids from Ferns on Protein Synthesis in Mouse Liver. Chem. Pharm. Bull., 17:1352, 1969.

    PubMed  CAS  Google Scholar 

  21. Otaka, T., Uchiyama, M., and Okui, S.: Stimulatory Effects of Insect-metamorphosing Steroids from Achyranthes and Cyathula on Protein Synthesis in Mouse Liver. Chem. Pharm. Bull., 16:2426, 1968.

    PubMed  CAS  Google Scholar 

  22. Reich, E., Franklin, R. M., Shatkin, A. J., and Tatum, E.L.: Effect of Actinomycin D on Cellular Nucleic Acid Synthesis and Virus Production. Science, 134:556–551, 1961.

    Article  PubMed  CAS  Google Scholar 

  23. Trakatellis, A. C., Axelrod, A. E., and Montjar, M.: Actinomycin D and Messenger RNA Turnover. Nature, 203:1134–1136, 1964.

    Article  PubMed  CAS  Google Scholar 

  24. Wettstein, F. O., Staehelin, T., and Noll, H.: Ribosomal Aggregate Engaged in Protein Synthesis: Characterization of the Ergosome. Nature, 197:430–435, 1963.

    Article  PubMed  CAS  Google Scholar 

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Authors
  1. Mitsuru Uchiyama
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  2. Tadahiko Otaka
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Editor information

Editors and Affiliations

  1. The University of Texas, Houston, Texas, 77025, USA

    Walter J. Burdette Ph.D., M.D. (Professor of Surgery) (Professor of Surgery)

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© 1974 Springer-Verlag New York Inc.

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Uchiyama, M., Otaka, T. (1974). Phytoecdysones and Protein Metabolism in Mammalia. In: Burdette, W.J. (eds) Invertebrate Endocrinology and Hormonal Heterophylly. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-65769-6_31

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  • DOI: https://doi.org/10.1007/978-3-642-65769-6_31

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-65771-9

  • Online ISBN: 978-3-642-65769-6

  • eBook Packages: Springer Book Archive

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