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Transfer of Maternal Leukocytes to the Infant by Human Milk

  • Chapter
Reproductive Immunology

Part of the book series: Current Topics in Microbiology and Immunology ((CT MICROBIOLOGY,volume 222))

Abstract

Human milk contains a complex immune system that consists not only of a host of soluble direct-acting antimicrobial agents (GOLDMAN and SMITH 1973), anti-in-flammatory factors (GOLDMAN et al. 1986), and immunomodulating agents (GOLDMAN 1993) but also of living cells. The discovery of leukocytes in human milk began with microscopic examinations of human milk by the first microscopist, ANTHONY VAN LEEWENHOEK (1695). His observations lay fallow until ALFRED DONNÉ (1837) the French physician who first adapted plate photography to microscopy, reported the presence of globules and granular bodies in human milk. Most of the globules were probably milk fat globules, myriads of which are normally found in human milk. Many years later when staining techniques became available, some of the corpuscles de Donné were found to be cells.

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Author information

Authors and Affiliations

  1. Department of Pediatrics, Immunology/Allergy Division, Children’s Hospital, University of Texas Medical Branch, 301 University Boulevard, Galveston, 77555-0369, TX, USA

    A. S. Goldman & R. M. Goldblum

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  1. A. S. Goldman
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  2. R. M. Goldblum
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Editors and Affiliations

  1. Department of Immunology, Microbiology, Pathology and Infectious Diseases Karolinska Institute Division of Pathology, F42 Huddinge University Hospital, Huddinge, S-141 86, Sweden

    Lars B. Olding M.D., Ph.D.

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© 1997 Springer-Verlag Berlin Heidelberg

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Goldman, A.S., Goldblum, R.M. (1997). Transfer of Maternal Leukocytes to the Infant by Human Milk. In: Olding, L.B. (eds) Reproductive Immunology. Current Topics in Microbiology and Immunology, vol 222. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-60614-4_10

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  • DOI: https://doi.org/10.1007/978-3-642-60614-4_10

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-64475-7

  • Online ISBN: 978-3-642-60614-4

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