Skip to main content
SpringerLink
Log in

Impact of Osteoarthritis on Quality of Life

  • Chapter
Osteoarthritis

Abstract

Osteoarthritis (OA) is characterized by alteration in the structure and function of a joint, and results from changes in articular cartilage, underlying bone and soft tissues [1]. Osteoarthritis is the most common rheumatic disorder, and the aging of the population will result in a significant increase in its prevalence [2]. In Western population, as much as one third of the adults aged 25 – 75 years have evidence of radiographic OA [2]. Although it does not reduce life expectancy significantly, OA results in pain, disability and quality of life (QoL) impairment. To a certain extent only these outcomes are accounted for by radiographic evidence of articular degeneration. Indeed, pain and disability are not always correlated with radiographic disease severity [3, 4]. Yet, only about 60% of patients with radiographic evidence of OA are symptomatic. The sensitivity of radiographic assessment to detect pathological changes of OA is low [5], and this may partly explain the discrepancy between radiographic changes and symptoms found in epidemiological studies. However, our understanding of the determinants of the disability in OA remains poor. The pathways that depict OA from biomechanical factors and pathology to pain and disability, and include the various factors and interventions that may intervene at every step of the illness have been recently reviewed [2, 6].

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Log in via an institution
Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 39.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 54.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. Altman RD (1997) The syndrome of osteoarthritis. J Rheumatol 24: 766–767

    PubMed  CAS  Google Scholar 

  2. Creamer P, Hochberg MC (1997) Osteoarthritis. Lancet 350: 503–509

    Article  PubMed  CAS  Google Scholar 

  3. Summers MN, Haley WE, Reveille JD, Alarcon GS (1988) Radiographic assessment and psychological variables as predictors of pain and functional impairment in osteoarthritis of the knee or hip. Arthritis Rheum 31: 204–209

    Article  PubMed  CAS  Google Scholar 

  4. McAlindon TE, Cooper C, Kirwan JR, Dieppe PA (1993) Determinants of disability in osteoarthritis of the knee. Ann Rheum Dis 52: 258–262

    Article  PubMed  CAS  Google Scholar 

  5. Rogers J, Watt I, Dieppe (1990) Comparison of visual and radiographic detection of bony changes at the knee joint. BMJ 300: 367–368

    Article  PubMed  CAS  Google Scholar 

  6. Sharma L, Felson DT (1998) Studying how osteoarthritis causes disability: nothing is simple. J Rheumatol 25: 1–4

    PubMed  CAS  Google Scholar 

  7. Bellamy N (1997) Osteoarthritis clinical trials: candidate variables and clinimetric properties. J Rheumatol 24: 768–778

    PubMed  CAS  Google Scholar 

  8. Bellamy N, Kirwan J, Boers M, Brooks P, Strand V, Tugwell P, Altman R, Brandt K, Dougados M, Lequesne M (1997) Recommendations for a core set of outcome measures for future phase III clinical trials in knee, hip and hand osteoarthritis. Consensus development at OMERACT III. J Rheumatol 24: 799–802

    PubMed  CAS  Google Scholar 

  9. Leplège A, Hunt S (1997) The problem of quality of life in medicine. JAMA 278: 47–50

    Article  PubMed  Google Scholar 

  10. Patrick DL, Bush JW, Chen MM (1973) Toward an operational definition of health. J Health Soc Behav 14: 6–23

    Article  PubMed  CAS  Google Scholar 

  11. Ware JE Jr (1984) Conceptualizing disease impact and treatment outcomes. Cancer 53: 2316–2326

    PubMed  Google Scholar 

  12. Bergner M (1985) Measurement of health status. Med Care 23: 696–704

    Article  PubMed  CAS  Google Scholar 

  13. Ware JE Jr (1987) Standards for validating health measures: definition and content. J Chron Dis 40: 473–480

    Article  PubMed  Google Scholar 

  14. Bergner M, Bobbitt RA, Carter WB, Gilson BS (1981) The sickness impact profile: development and final revision of a health status measure. Med Care 19: 787–805

    Article  PubMed  CAS  Google Scholar 

  15. Ware JE Jr, Sherbourne CD (1992) The MOS 36-item short-form health survey (SF-36), I: conceptual framework and item selection. Med Care 30: 473–483

    Article  PubMed  Google Scholar 

  16. McHorney CA, Ware JE, Lu JFR, Sherbourne CD (1994) The MOS 36-item short-form health survey (SF-36), III: tests of data quality, scaling assumptions, and reliability across diverse patient groups. Med Care 32: 40–66

    Article  PubMed  CAS  Google Scholar 

  17. McHorney CA, Ware JE Jr, Raczek AE (1993) The MOS 36-item short-form health survey (SF-36), II: psychometric and clinical tests of validity in measuring physical and mental health conditions. Med Care 31: 247–263

    Article  PubMed  CAS  Google Scholar 

  18. Hunt SM, McKenna SP, McEwen J, Williams P, Papp E (1981) The Nottingham health profile: subjective health status and medical consultations. Soc Sci Med 15A: 221–229

    Google Scholar 

  19. Kaplan RM, Bush JW, Berry CC (1976) Health status: types of validity for an index of well-being. Health Serv Res 11: 478–507

    PubMed  CAS  Google Scholar 

  20. Kind P (1996) The EuroQoL instrument: an index of health-related quality of life. In: Spilker B. Quality of Life and Pharmacoeconomics in Clinical Trials. Second edition. Lippincott-Raven Publishers pp 191–201

    Google Scholar 

  21. Fries JF, Spitz PW, Young DY (1982) The dimensions of health outcomes: the health assessment questionnaire, disability and pain scales. J Rheumatol 9: 789–793

    PubMed  CAS  Google Scholar 

  22. Bellamy N, Buchanan WW, Goldsmith CH, Campbell J, Stitt LW (1988) Validation study of WOMAC: a health status instrument for measuring clinically important patient relevant outcomes to antirheumatic drug therapy in patients with osteoarthritis of the hip or knee. J Rheumatol 15: 1833–1840

    PubMed  CAS  Google Scholar 

  23. Bellamy N, Kean WF, Buchanan WW, Gerecz-Simon E, Campbell J (1992) Double blind randomized controlled trial of sodium meclofenamate (meclomen) and diclofenac sodium (voltaren): post validation reapplication of the WOMAC osteoarthritis index. J Rheumatol 19: 153–159

    PubMed  CAS  Google Scholar 

  24. Bellamy N, Campbell J, Stevens J, Pilch L, Stewart C, Mahmood Z (1997) Validation study of a computerized version of the Western Ontario and McMaster Universities VA3.0 Osteoarthritis Index. J Rheumatol 24: 2413–2415

    PubMed  CAS  Google Scholar 

  25. Bellamy N, Buchanan WW, Goldsmith CH, Campbell J, Duku E (1990) Signal measurement strategies: are they feasible and do they offer any advantage in outcome measurement in osteoarthritis? Arthritis Rheum 33: 739–745

    Article  PubMed  CAS  Google Scholar 

  26. Lequesne MG, Méry C, Samson M, Gérard P (1987) Indexes of severity for osteoarthritis of the hip and knee. Scand J Rheumatol [Suppl] 65: 85–89

    Article  CAS  Google Scholar 

  27. Lequesne M, Samson M (1991) Indices fonctionnels pour la coxarthrose et la gonarthrose. In: De Sèze S, Ryckewaert A, Kahn MF, Kuntz D, Dryll A, Guérin C (eds) L’actualité rheumatologique présentée au praticien. Expansion Scientifique Française, pp 195–206

    Google Scholar 

  28. Lequesne M (1997) The algofunctional indices for the hip and knee osteoarthritis. J Rheumatol 24: 779–781

    PubMed  CAS  Google Scholar 

  29. Meenan RF, Gertman PM, Mason JH (1980) Measuring health status in arthritis: the arthritis impact measurement scales. Arthritis Rheum 23: 146–152

    Article  PubMed  CAS  Google Scholar 

  30. Meenan RF, Gertman PM, Mason JH, Dunaif R (1982) The arthritis impact measurement scales: further investigations of a health status measure. Arthritis Rheum 25: 1048–1053

    Article  PubMed  CAS  Google Scholar 

  31. Mason JH, Anderson JJ, Meenan RF (1989) Applicability of a health status model to osteoarthritis. Arthritis Care Res 2: 89–93

    Article  PubMed  CAS  Google Scholar 

  32. Meenan RF, Mason JH, Anderson JJ, Guccione AA, Kazis LE (1992) The content and properties of a revised and expanded arthritis impact measurement scales health status questionnaire. Arthritis Rheum 35: 1–10

    Article  PubMed  CAS  Google Scholar 

  33. Tugwell P, Bombardier C, Buchanan WW, Goldsmith CH, Grace E, Hanna B (1987) The MACTAR patient preference disability questionnaire. An individualized functional priority approach for assessing improvement in physical disability in clinical trials in rheumatoid arthritis. J Rheumatol 14: 446–451

    PubMed  CAS  Google Scholar 

  34. Laupacis A, Bourne R, Rorabeck C, Feeny D, Wong C, Tugwell P, Leslie K, Bullas R (1993) The effect of elective total hip replacement of health-related quality of life. J Bone Joint Surg 75-A: 1619–1626

    Google Scholar 

  35. O’Boyle CA, McGee H, Hickey A, O’Malley K, Joyce CRB (1992) Individual quality of life in patients undergoing hip replacement. Lancet 339: 1088–1091

    Article  PubMed  Google Scholar 

  36. Hopman-Rock M, Bijlsma JW, Kraaimaat FW, Hofman A, Odding E (1996) Physical and psychosocial disability in elderly subjects in relation to pain in the hip and/or knee. J Rheumatol 23: 1037–1044

    PubMed  CAS  Google Scholar 

  37. De Bock GH, Mulder JD, Touw-Otten F, Kaptein AA (1995) Health-related quality of life in patients with osteoarthritis in a family practice setting. Arthritis Care Res 8: 88–93

    Article  PubMed  Google Scholar 

  38. Lequesne M, Samson M, Gérard P, Méry (1990) Indices algo-fonctionnels pour le suivi des arthroses de la hanche et du genou. Rev Rhum Mal Osteoartic 57: 32S-36S

    PubMed  CAS  Google Scholar 

  39. Mattsson E, Brostrom LA (1991) The physical and psychosocial effect of moderate osteoarthrosis of the knee. Scand J Rehabil Med 23: 215–218

    PubMed  CAS  Google Scholar 

  40. Anderson JJ, Firschein HE, Meenan RF (1989) Sensitivity of a health status measure to short-term clinical changes in arthritis. Arthritis Rheum 32: 844–850

    Article  PubMed  CAS  Google Scholar 

  41. Thorsen H, McKenna SP, Gottschalk L (1993) The Danish version of the Nottingham health profile: ist adaptation and reliability. Scand J Prim Health Care 11: 124–129

    Article  PubMed  CAS  Google Scholar 

  42. Wiklund I, Romanus B (1991) A comparison of quality of life before and after arthroplasty in patients who had arthrosis of the hip joint. J Bone Joint Surg 73-A: 765–769

    Google Scholar 

  43. Hawley DJ, Wolfe (1991) Pain, disability and pain/disability relationships in seven rheumatic disorders: a study of 1522 patients. J Rheumatol 18: 1552–1557

    PubMed  CAS  Google Scholar 

  44. Yelin E, Lubeck D, Holman H, Epstein W (1987) The impact of rheumatoid arthritis and osteoarthritis: the activities of patients with rheumatoid arthritis and osteoarthritis compared to controls. J Rheumatol 14: 710–717

    PubMed  CAS  Google Scholar 

  45. Callahan LF, Smith WJ, Pincus T (1989) Self-report questionnaires in five rheumatic diseases. Comparisons of health status constructs and associations with formal education level. Arthritis Care Res 2: 122–131

    Article  PubMed  CAS  Google Scholar 

  46. Pouchot J, Guillemin F, Coste J, Brégeon C, Sany J, and the French “Quality of Life in Rheumatology” Group (1996) Validity, reliability, and sensitivity to change of a French version of the Arthritis Impact Measurement scales 2 (AIMS2) in patients with rheumatoid arthritis treated with methotrexate. J Rheumatol 23: 52–60

    PubMed  CAS  Google Scholar 

  47. Wiklund I, Romanus B, Hunt SM (1988) Self-assessed disability in patients with arthrosis of the hip joint. Reliability of the Swedish version of the Nottingham health profile. Int Disab Studies 10: 159–163

    Article  CAS  Google Scholar 

  48. Wolfe F, Hawley DJ (1997) Measurement of the quality of life in rheumatic disorders using the EuroQoL. Br J Rheumatol 36: 786–793

    Article  PubMed  CAS  Google Scholar 

  49. Gordon G (1988) Effects of piroxicam on quality of life of patients with osteoarthritis. Consultant (suppl) 28: 4–10

    Google Scholar 

  50. Bradley JD, Brandt KD, Katz BP, Kalasinski LA, Ryan SI (1991) Comparison of an antiinflammatory dose of ibuprofen, an analgesic dose of ibuprofen, and acetaminophen in the treatment of patients with osteoarthritis of the knee. N Engl J Med 325: 87–91

    Article  PubMed  CAS  Google Scholar 

  51. Kovar PA, Allegrante JP, MacKenzie CR, Peterson MGE, Gutin B, Charlson ME (1992) Supervised fitness walking in patients with osteoarthritis of the knee. Ann Intern Med 116: 529–534

    PubMed  CAS  Google Scholar 

  52. Weinberger M, Tierney WM, Booher P, Katz BP (1989) Can the provision of information to patients with osteoarthritis improve functional status? A randomized, controlled trial. Arthritis Rheum 32: 1577–1583

    Article  PubMed  CAS  Google Scholar 

  53. Mazzuca SA, Hanna M, Byrd D, Chambers M, Katz BP, Brandt KD (1997) Effects of self-care education on the health status of inner-city patients with osteoarthritis of the knee. Arthritis Rheum 40: 1466–1474

    Article  PubMed  CAS  Google Scholar 

  54. Nguyen M, Dougados M, Revel M (1997) Prolonged effects of 3 week therapy in a spa resort on lumbar spine, knee and hip osteoarthritis: follow-up after 6 months. A randomized controlled trial. Br J Rheumatol 36: 77–81

    Article  PubMed  CAS  Google Scholar 

  55. Lequesne M, Brandt K, Bellamy N, Moskowitz R, Menkès CJ, Pelletier JP, Altman R (1994) Guidelines for testing slow-acting and disease-modifying drugs in osteoarthritis. J Rheumatol [Suppl]41: 65–71

    CAS  Google Scholar 

  56. Burkhardt D, Ghosh P (1987) Laboratory evaluation of antirheumatic drugs as potential chondroprotective agents. Semin Arthritis Rheum 17: 3–34

    PubMed  CAS  Google Scholar 

  57. Ravaud P, Dougados M (1997) Radiographic assessment in osteoarthritis. J Rheumatol 24: 786–791

    PubMed  CAS  Google Scholar 

  58. Puhl W, Bernau A, Greiling H, Köpcke W, Pförringer W, Steck KJ, Zacher J, Scharf HP (1993) Intra-articular sodium hyaluronate in osteoarthritis of the knee: a multicenter, double-blind study. Osteoarthritis Cartilage 1: 233–241

    Article  PubMed  CAS  Google Scholar 

  59. Listrat V, Dougados M, Amor B, Simonnet J, Bonvarlet JP, Patarnello F, Ayral X (1997) Arthroscopic evaluation of potential structure modifying activity of hyaluronan (Hyalgan) in osteoarthritis of the knee. Osteoarthritis Cartilage 5: 153–160

    Article  PubMed  CAS  Google Scholar 

  60. Liang MH, Cullen KE, Larson MG, Thompson MS, Schwartz JA, Fossel AH, Roberts WN, Sledge CB (1986) Cost-effectiveness of total joint arthroplasty in osteoarthritis. Arthritis Rheum 29: 937–943

    Article  PubMed  CAS  Google Scholar 

  61. Liang MH, Larson MG, Cullen KE, Schwartz JA (1985) Comparative measurement efficiency and sensitivity of five health status instruments for arthritis research. Arthritis Rheum 28: 542–547

    Article  PubMed  CAS  Google Scholar 

  62. Katz JN, Phillips CB, Poss R, Harrast JJ, Fossel AH, Liang MH, Sledge CB (1995) The validity and reliability of a total hip arthroplasty outcome evaluation questionnaire. J Bone Joint Surg 77-A: 1528–1534

    Google Scholar 

  63. Towheed TE, Hochberg MC (1996) Health-related quality of life after total hip replacement. Semin Arthritis Rheum 26: 483–491

    Article  PubMed  CAS  Google Scholar 

  64. Stucki G, Katz JN, Philipps C, Liang MH (1995) The Short Form-36 is preferable to the SIP as a generic health status measure in patients undergoing elective total hip arthroplasty. Arthritis Care Res 8: 174–181

    Article  PubMed  CAS  Google Scholar 

  65. Dawson J, Fitzpatrick R, Murray D, Carr A (1998) Questionnaire on the perceptions of patients about total knee replacement. J Bone Joint Surg 80-6: 63–69

    Article  CAS  Google Scholar 

  66. Garellick G, Malchau H, Herberts P, Hansson E, Axelsson H, Hansson T (1998) Life expectancy and cost utility after total hip replacement. Clin Orthop 346: 141–151

    PubMed  Google Scholar 

  67. Chang RW, Hazen GB, Pellisier JM (1996) A cost-effectiveness analysis of total hip arthroplasty for osteoarthritis of the hip. JAMA 275: 858–865

    Article  PubMed  CAS  Google Scholar 

  68. Drewett RF, Minns RJ, Sibly TF (1992) Measuring outcome of total knee replacement using quality of life indices. Ann R Coll Surg Engl 74: 286–290

    PubMed  CAS  Google Scholar 

  69. Bennett KJ, Goldsmith CH, Smith F, Moran LA, Torrance GW (1997) Health state utilities in knee replacement surgery: the development and evaluation of McKnee. J Rheumatol 24: 1796–1805

    PubMed  CAS  Google Scholar 

  70. Lavernia CJ, Gachupin-Garcia A, Guzman JF (1997) Cost effectiveness and quality of life in knee arthroplasty. Clin Orthop 345: 134–139

    PubMed  Google Scholar 

  71. Ruchlin HS, Paget SA, Elkin EB (1997) Assessing cost-effectiveness analyses in rheumatoid arthritis and osteoarthritis. Arthritis Care Res 10: 413–421

    Article  PubMed  CAS  Google Scholar 

  72. Guyatt GH, Feeny DH, Patrick DL (1993) Measuring health-related quality of life. Ann Intern Med 118: 622–629

    PubMed  CAS  Google Scholar 

  73. Weinberger M, Samsa GP, Tierney WM, Belyea MJ, Hiner SL (1992) Generic versus disease specific health status measures: comparing the Sickness Impact Profile and the Arthritis Impact Measurement Scales. J Rheumatol 19: 543–546

    PubMed  CAS  Google Scholar 

  74. Kantz ME, Harris WJ, Levitsky K, Ware J, Ross Davies A (1992) Methods for assessing condition-specific and generic functional status outcomes after total knee replacement. Med Care 30: MS240-MS252

    Article  PubMed  CAS  Google Scholar 

  75. Hawker G, Melfi C, Paul J, Green R, Bombardier C (1995) Comparison of a generic (SF-36) and a disease specific (WOMAC) instrument in the measurement of outcomes after knee replacement surgery. J Rheumatol 22: 1193–1196

    PubMed  CAS  Google Scholar 

  76. Bombardier C, Coyte P, Wright J, Hawker G, Green R, Paul J, Melfi CA (1995) Comparison of a generic and a disease-specific measure of pain and physical function after knee replacement surgery. Med Care (suppl) 33: AS131-AS144

    PubMed  CAS  Google Scholar 

  77. Patrick DL, Deyo RA (1989) Generic and disease-specific measures in assessing health status and quality of life. Med Care 27: 8217–8232

    Article  Google Scholar 

  78. Kirshner B, Guyatt G (1985) A methodological framework for assessing health indices. J Chron Dis 38: 27–36

    Article  PubMed  CAS  Google Scholar 

  79. Fitzpatrick R, Fletcher A, Gore S, Jones D, Spiegelhalter D, Cox D (1992) Quality of life measures in health care. I: applications and issues in assessment. BMJ 305: 1074–1077

    Article  PubMed  CAS  Google Scholar 

  80. Coste J, Fermanian J, Venot A (1995) Methodological and statistical problems in the construction of composite measurement scales. A survey of six medical and epidemiological journals. Stat Med 14: 331–345

    Article  PubMed  CAS  Google Scholar 

  81. Wright JG, Young NL (1997) A comparison of different indices of responsiveness. J Clin Epidemiol 50: 239–246

    Article  PubMed  CAS  Google Scholar 

  82. Coste J, Guillemin F, Pouchot J, Fermanian J (1997) The methodological approaches to shortening composite measurement scales. J Clin Epidemiol 50: 247–252

    Article  PubMed  CAS  Google Scholar 

  83. Wallston KA, Brown GK, Stein MJ, Dobbins CJ (1989) Comparing the short and long versions of the Arthritis Impact Measurement Scales. J Rheumatol 16: 1105–1109

    PubMed  CAS  Google Scholar 

  84. Lorish C, Abraham N, Austin JS, Bradley LA, Alarcon GS (1991) A comparison of the full and short versions of the Arthritis Impact Measurement Scales. Arthritis Care Res 4: 168–173

    Article  PubMed  CAS  Google Scholar 

  85. Guillemin F, Coste J, Pouchot J, Ghézail M, Brégeon C, Sany J, and the French Quality of Life in Rheumatology Group (1997) The AIMS2-SF. A short form of the Arthritis Impact Measurement Scales 2. Arthritis Rheum 40: 1267–1274

    PubMed  CAS  Google Scholar 

  86. Guillemin F, Bombardier C, Beaton D (1993) Cross-cultural adaptation of health-related quality of life measures: literature review and proposed guidelines. J Clin Epidemiol 46: 1417–1432

    Article  PubMed  CAS  Google Scholar 

  87. Guillemin F (1995) Cross-cultural adaptation and validation of health status measures. Scand J Rheumatol 24: 61–63

    Article  PubMed  CAS  Google Scholar 

Download references

Authors
  1. J. Pouchot
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. J. Coste
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. F. Guillemin
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

Copyright information

© 1999 Springer-Verlag Berlin Heidelberg

About this chapter

Cite this chapter

Pouchot, J., Coste, J., Guillemin, F. (1999). Impact of Osteoarthritis on Quality of Life. In: Osteoarthritis. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-60026-5_17

Download citation

  • DOI: https://doi.org/10.1007/978-3-642-60026-5_17

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-65127-7

  • Online ISBN: 978-3-642-60026-5

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics

Search

Navigation