Abstract
The majority of human hematopoietic malignancies carry non-random chromosomal translocations. The deregulation of specific genes that occurs as a consequence of translocations has been shown to be central to the pathogenesis of such diseases. In addition, each translocation is often characteristic of a particular subtype of neoplasm, thus making chromosomal translocations valuable as diagnostic markers of disease.
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© 2001 Springer-Verlag Berlin Heidelberg
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Bohling, S.D., Elenitoba-Johnson, K.S.J. (2001). Development of PCR-Based Assays for the Detection of Chromosomal Translocations Using SYBR Green I. In: Meuer, S., Wittwer, C., Nakagawara, KI. (eds) Rapid Cycle Real-Time PCR. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-59524-0_25
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DOI: https://doi.org/10.1007/978-3-642-59524-0_25
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-540-66736-0
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