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Basic Principles of Antisense Therapeutics

  • Chapter
Antisense Research and Application

Part of the book series: Handbook of Experimental Pharmacology ((HEP,volume 131))

Abstract

During the past few years, interest in developing antisense technology and in exploiting it for therapeutic purposes has been intense. Although progress has been gratifyingly rapid, the technology remains in its infancy and the questions that remain to be answered still outnumber the questions for which there are answers. Appropriately, considerable debate continues about the breadth of the utility of the approach and about the type of data required to “prove that a drug works through an antisense mechanism.”

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    Stanley T. Crooke M.D., Ph.D.

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Crooke, S.T. (1998). Basic Principles of Antisense Therapeutics. In: Crooke, S.T. (eds) Antisense Research and Application. Handbook of Experimental Pharmacology, vol 131. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-58785-6_1

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  • Print ISBN: 978-3-642-63730-8

  • Online ISBN: 978-3-642-58785-6

  • eBook Packages: Springer Book Archive

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