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Protection of Neuronal and Cardiac Cells by HSP27

  • Chapter
Small Stress Proteins

Part of the book series: Progress in Molecular and Subcellular Biology ((PMSB,volume 28))

Abstract

One of the aspects of heat shock protein biology, which has attracted the most attention, is their protective effect when over-expressed (for reviews see Latchman 1991; Yellon and Latchman 1992; Parsell and Lindquist 1993; Benjamin and McMillan 1998; Gray, et al. 1999). As well as being of interest in itself, this phenomenon is evidently of importance in medical terms, since it may be possible to achieve a therapeutic benefit in diseases such as stroke or cardiac ischaemia by inducing HSP over-expression either pharmacologically or using gene delivery procedures.

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Author information

Authors and Affiliations

  1. Institute of Child Health, University College London, 30 Guilford Street, London, WC1N 1EH, UK

    David S. Latchman

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  1. David S. Latchman
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Editors and Affiliations

  1. Laboratoire Stress Oxydant Chaperons et Apoptose Centre de Génétique Moléculaire et Cellulaire CNRS UMR-5534, Université Claude Bernard Lyon-I, 43, Bd. du 11 Novembre, 69622, Villeurbanne, France

    André-Patrick Arrigo

  2. Institut für Physiologische Chemie Abteilung für Angewandte Molekularbiologie, Johannes Gutenberg-Universität, Duesbergweg 6, 55099, Mainz, Germany

    W. E. G. Müller

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© 2002 Springer-Verlag Berlin Heidelberg

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Latchman, D.S. (2002). Protection of Neuronal and Cardiac Cells by HSP27. In: Arrigo, AP., Müller, W.E.G. (eds) Small Stress Proteins. Progress in Molecular and Subcellular Biology, vol 28. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-56348-5_14

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  • DOI: https://doi.org/10.1007/978-3-642-56348-5_14

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-62708-8

  • Online ISBN: 978-3-642-56348-5

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