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Insulin-Like Growth Factors

  • Chapter
Peptide Growth Factors and Their Receptors I

Part of the book series: Handbook of Experimental Pharmacology ((HEP,volume 95 / 1))

Abstract

Until recently, insulin-like growth factors (or, as they were originally known, somatomedins) were thought to be produced in the liver in response to growth hormone, to circulate in the blood, and to mediate the effects of growth hormone (GH) on skeletal cartilage to promote bone elongation during childhood (Salmon and Daughaday 1957).

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  1. Laboratory of Chemoprevention, National Cancer Institute, Bldg. 41, Room C-629, 20892, Bethesda, MD, USA

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© 1990 Springer-Verlag Berlin Heidelberg

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Rechler, M.M., Nissley, S.P. (1990). Insulin-Like Growth Factors. In: Sporn, M.B., Roberts, A.B. (eds) Peptide Growth Factors and Their Receptors I. Handbook of Experimental Pharmacology, vol 95 / 1. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-49295-2_6

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  • DOI: https://doi.org/10.1007/978-3-642-49295-2_6

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  • Print ISBN: 978-3-642-49297-6

  • Online ISBN: 978-3-642-49295-2

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