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Hyperinsulinism

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Physician's Guide to the Diagnosis, Treatment, and Follow-Up of Inherited Metabolic Diseases

Abstract

Hyperinsulinism of infancy (HI) is the most common cause of recurrent and severe hypoglycaemia in the neonatal and infancy periods. The biochemical basis of this disorder is characterised by the excessive and inappropriate secretion of insulin in relation to the prevailing blood glucose concentration. The inappropriate insulin secretion leads to severe and recurrent hypoglycaemia. HI can be either persistent or transient.

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Authors and Affiliations

  1. Department of Endocrinology, Great Ormond Street, Children’s Hospital, London, WC1N 1EH, UK

    Khalid Hussain

  2. Departments of Pediatrics, Hôpital Necker Enfants Malades, Université Paris-Descartes, Faculté de Médecine, Paris Descarte, 75743, Paris, France

    Pascale De Lonlay

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  1. Khalid Hussain
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  2. Pascale De Lonlay
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Correspondence to Khalid Hussain .

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Editors and Affiliations

  1. Department of General Pediatrics, University Children's Hospital, Division of Inborn Metabolic Diseases, Heidelberg, Germany

    Nenad Blau

  2. Laboratory Genetic Metabolic Diseases, University of Amsterdam Academic Medical Centre, Amsterdam, The Netherlands

    Marinus Duran

  3. Section of Clinical Pharmacology, Washington State University, Spokane, Washington, USA

    K Michael Gibson

  4. Division of Metabolism, Department of Pediatric Medicine, Bambino Gesù Children’s Research Hospital, Rome, Italy

    Carlo Dionisi Vici

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Hussain, K., De Lonlay, P. (2014). Hyperinsulinism. In: Blau, N., Duran, M., Gibson, K., Dionisi Vici, C. (eds) Physician's Guide to the Diagnosis, Treatment, and Follow-Up of Inherited Metabolic Diseases. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-40337-8_21

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  • DOI: https://doi.org/10.1007/978-3-642-40337-8_21

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