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Squamous Cell Carcinoma

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Reflectance Confocal Microscopy for Skin Diseases

Abstract

Cutaneous squamous cell carcinoma (SCC), one of the most common malignant neoplasms in fair-skinned individuals, classically presents as a pink to red scaly papule or plaque that at times can be difficult to distinguish clinically from other skin lesions, such as basal cell carcinomas, irritated seborrheic keratoses, lichen planus-like keratoses, or inflammatory skin diseases like psoriasis. Pigmented SCC clinically presents as a variegated brown papule or plaque with variable amounts of scale and can be confused with superficial spreading melanoma [1]. Dermoscopy can aid in the correct diagnosis when characteristic features of SCC such as vessels as dots or coiled (glomerular) vessels and a scaly surface are present; however, significant surface scale can obscure the vascular structures [2–5].

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References

  1. Cameron A, Rosendahl C, Tschandl P, Riedl E, Kittler H Dermatoscopy of pigmented Bowen’s disease. J Am Acad Dermatol. 2010 Apr;62(4):597-604. Epub 2010 Jan 15.

    Google Scholar 

  2. Zalaudek I, Argenziano G, Leinweber B, Citarella L, Hofmann-Wellenhof R, Malvehy J, Puig S, Pizzichetta MA, Thomas L, Soyer HP, Kerl H (2004) Dermoscopy of Bowen’s disease. Br J Dermatol 150:1112–1116

    Article  PubMed  CAS  Google Scholar 

  3. Bugatti L, Filosa G, De Angelis R (2004) Dermoscopic observation of Bowen’s disease. JEADV 18:572–574

    PubMed  CAS  Google Scholar 

  4. Pan Y, Chamberlain A, Bailey M, Chong A, Haskett M, Kelly J (2008) Dermatoscopy aids in the diagnosis of the solitary red scaly patch or plaque—features distinguishing superficial basal cell carcinoma, intraepidermal carcinoma, and psoriasis. J Am Acad Dermatol 59(2):268–274

    Article  PubMed  Google Scholar 

  5. Argenziano G, Zalaudek I, Corona R, Sera F, Cicale L, Petrillo G, Ruocco E, Hofmann-Wellenhof R, Soyer HP (2004) Vascular structures in skin tumors: a dermoscopy study. Arch Dermatol 140:1485–1489

    Article  PubMed  Google Scholar 

  6. Satter EK (2007) Pigmented squamous cell carcinoma. Am J Dermatopathol 29(5):486–489

    Article  PubMed  Google Scholar 

  7. Ackerman AB, Mones JM (2006) Solar (actinic) keratosis is squamous cell carcinoma. Br J Dermatol 155:9–22

    Article  PubMed  CAS  Google Scholar 

  8. Rishpon A, Kim N, Scope A, Porges L, Oliviero M, Braun R, Marghoob A, Alessi-Fox C, Rabinovitz H (2009) Reflectance confocal microscopy criteria for squamous cell carcinomas and actinic keratoses. Arch Dermatol 145(7):766–772

    Article  PubMed  Google Scholar 

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Correspondence to Theresa Cao .

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© 2012 Springer-Verlag Berlin Heidelberg

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Cao, T., Oliviero, M., Rabinovitz, H.S. (2012). Squamous Cell Carcinoma. In: Hofmann-Wellenhof, R., Pellacani, G., Malvehy, J., Soyer, H. (eds) Reflectance Confocal Microscopy for Skin Diseases. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-21997-9_23

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  • DOI: https://doi.org/10.1007/978-3-642-21997-9_23

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  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-21996-2

  • Online ISBN: 978-3-642-21997-9

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