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Production of Organic Acids by Filamentous Fungi

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Industrial Applications

Part of the book series: The Mycota ((MYCOTA,volume 10))

Abstract

This chapter summarizes current knowledge on the biochemical and physiological events leading to the massive accumulation of organic acids by filamentous fungi, particularly Aspergillus niger under industrially comparable conditions, thereby particularly emphasizing the roles of: (1) metabolic flux and its control and (2) critical fermentation variables. The value of genome information for metabolic analysis and genomic approaches in understanding these fermentations is also discussed.

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Notes

  1. 1.

    5Fermentation is here used in a more general sense and means a “metabolic production process” as such and does not refer to an anaerobic sugar conversion process leading mainly to ethanol (see alcohol fermentation in Chapter 2).

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Authors and Affiliations

  1. Research Area Gene Technology and Applied Biochemistry, Institute of Chemical Engineering, Technische Universität Wien, Getreidemarkt 9/166, 1060, Vienna, Austria

    Christian P. Kubicek

  2. TNO Quality of Life, Utrechtseweg 48, 3700, AJ, Zeist, The Netherlands

    Peter Punt

  3. Sylvius Laboratory, Institute of Biology, Leiden University, Sylviusweg 72, 2333, BE, Leiden, The Netherlands

    Jaap Visser

  4. Fungal Genetics and Technology Consultancy, 396, 6700, AJ, Wageningen, The Netherlands

    Jaap Visser

Authors
  1. Christian P. Kubicek
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  2. Peter Punt
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  3. Jaap Visser
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Correspondence to Christian P. Kubicek .

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  1. , Department of Biotechnology, International Graduate School of Zittau, Markt 23, Zittau, 02763, Sachsen, Germany

    Martin Hofrichter

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Kubicek, C.P., Punt, P., Visser, J. (2011). Production of Organic Acids by Filamentous Fungi. In: Hofrichter, M. (eds) Industrial Applications. The Mycota, vol 10. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-11458-8_10

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