Abstract
Crystalline bacterial cell surface layers (S-layers) are key structural components of many bacterial and archaeal cell envelopes. The broad application potential of S-layers in nanobiotechnology is based on specific intrinsic features of the monomolecular arrays which can be split into their constituting subunits and reassembled in suspension or on suitable surfaces (e.g., polymers, metals, silicon wafers) or interfaces (e.g., lipid films, liposomes). S-layers also represent a unique structural basis and patterning element for generating more complex supramolecular structures involving all major classes of biological molecules. Thus, S-layers fulfil key requirements as building blocks and patterning elements for the production of new supramolecular materials and nanoscale devices as required in molecular nanotechnology, nanobiotechnology and biomimetics.
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Acknowledgements
Financial support from the Austrian Science Fund (FWF, projects P18013-B10 (P.M.), P18510-B12 (E.M.E.), P19047-B12 (C.S), and 20256-B11 (B.S.)), the Erwin-Schrödinger Society for Nanosciences, the FP6 EC STREP NASSAP (project 13352; to U.B.S.), the Hochschuljubiläumsstiftung der Stadt Wien, project H-1809/2006 (to C.S.), and the Air Force Office of Scientific Research, USA (AFOSR, projects F49620-03-1-0222 (U.B.S.), FA9550-06-1-0208 (D.P.), and FA9550-07-1-0313 (U.B.S.)) is gratefully acknowledged.
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Sleytr, U.B. et al. (2010). Prokaryotic Cell Wall Components: Structure and Biochemistry. In: König, H., Claus, H., Varma, A. (eds) Prokaryotic Cell Wall Compounds. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-05062-6_16
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