Skip to main content
SpringerLink
Log in

Maligne viszerale Tumoren des Kindes

  • Chapter
Praxis der Viszeralchirurgie Onkologische Chirurgie

Zusammenfassung

Dieses Kapitel befasst sich mit den embryonalen viszeralen Tumoren Neuroblastom, Nephroblastom (Wilms-Tumor), Hepatoblastom und Pankreatoblastom. Diese hochmalignen Neoplasien kommen bei Erwachsenen nicht vor und manifestieren sich bevorzugt im Säuglings- und Kleinkindesalter. Sie sprechen in der Regel gut auf Chemotherapie und zum Teil auf Bestrahlung an. Deshalb ist die Chirurgie stets ein Teil eines umfassenden Therapieregimes, das sich streng nach den Therapieoptimierungsprotokollen der Gesellschaft für Pädiatrische Onkologie und Hämatologie richten sollte.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Log in via an institution
Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 269.00
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

Similar content being viewed by others

Literatur

  • Ambros PF (2000) Concept of tumorigenesis and regression. In: Brodeur GM, Sawada T, Tsuchida Y, Voute PA (eds) Neuroblastoma. Elsevier, Amsterdam, pp 21–32

    Google Scholar 

  • Argani P, Perlman EJ, Breslow NE, Browning NG, Green DM, D’Angio GJ, Beckwith JB (2000) Clear cell sarcoma of the kidney. A review of 351 cases from the National Wilms Tumor Study Group Pathology Center. Am J Surg Pathol 24: 4–18

    Article  CAS  PubMed  Google Scholar 

  • Brodeur GM, Maris JM (2002) Neuroblastoma. In: Pizzo PA, Poplack DG (eds) Principles and practice of pediatric oncology. Lippincott, Philadelphia, pp 895–938

    Google Scholar 

  • Cecchetto G, Mosseri V, De Bernardi B, Helardot P, Monclair T, Costa E, Horcher E, Neuenschwander S, Tom P, Rizzo A, Michon J, Holmes K (2005) Surgical risk factors in primary surgery for localized neuroblastoma; the LNESG1 study of the European International Society of Pediatric Oncology Neuroblastoma Group. J Clin Oncol 33:8483–8489

    Article  Google Scholar 

  • Cohn SL, Pearson AD, London WB, Monclair T, Ambros PF, Brodeur GM, Faldum A, Hero B, Ikehara T, Machin D, Mosseri V, Simon T, Garaventa A, Castel V, Matthay KK; INRG Task Force (2009) The International Neuroblastoma Risk Group (INRG) classification system: an INRG Task Force Report. J Clin Oncol 27:289–297

    Article  PubMed  Google Scholar 

  • Defachelles AS, Martin-de Lassalle E, Boutard P, Nelken B, Schneider P, Patte C (2001) Pankreatoblastoma in childhood: clinical course and therapeutic management of seven patients. Med Pediatr Oncol 37: 47–52

    Article  CAS  PubMed  Google Scholar 

  • Gadner H, Gaedicke G, Niemeyer C, Ritter J (2006) Pädiatische Hämatologie und Onkologie, Springer, Berlin Heidelberg New York

    Book  Google Scholar 

  • Godzinski J, Tournade MF, de Kraker J et al. (1998) Rarity of surgical complications after postchemotherapy nephrectomy for nephroblastoma. Experience of the International Society of Paediatric Oncology — Trial and Study »IOP-9«. Eur J Pediatr Surg 8: 83–86

    Article  CAS  PubMed  Google Scholar 

  • Graf N, Tournade MF, de Kraker J (2000) The role of preoperative chemotherapy in the management of Wilms’ tumor. The SIOP studies. International Society of Pediatric Oncology. Urol Clin North Am 27: 443–454

    Article  CAS  PubMed  Google Scholar 

  • Grundy PE, Green D, Coppes MJ, Breslow NE, Ritchey ML, Perlman EJ, Macklis RM (2002) Renal tumors. In: Pizzo PA, Poplack DG (eds) Principles and practice of pediatric oncology. Lippincott, Philadelphia, pp 865–894

    Google Scholar 

  • Häberle B, Bode U, von Schweinitz D (2003) Differenzierte Therapieansätze für Hoch-und Standardrisiko Hepatoblastome. Klin Pädiatr 215: 159–165

    Article  PubMed  Google Scholar 

  • Haecker FM, von Schweinitz D, Harms D, Buerger D, Graf N (2003) Partial nephrectomy for unilateral Wilms tumor: results of study SIOP 93-01/GPOH. J Urol 170: 939–944

    Article  PubMed  Google Scholar 

  • Kaatsch P, Spix C (2008) Jahresbericht — Annual Report 2006/2007 (1980–2006). Deutsches Kinderkrebsregister, Mainz

    Google Scholar 

  • Kerbl R, Urban CE, Ambros IM et al. (2003) Neuroblastoma mass screening in late infancy: insights into the biology of neuroblastic tumors. J Clin Oncol 21: 4228–4234

    Article  PubMed  Google Scholar 

  • Leavey PJ, Odom LF, Poole M, McNeely L, Tyson RW, Haase GM (1997) Intra-operative radiation therapy in pediatric neuroblastoma. Med Pediatr Oncol 28: 424–428

    Article  CAS  PubMed  Google Scholar 

  • Monclair T, Brodeur GM, Ambros PF, Brisse HJ, Cecchetto G, Holmes K, Kaneko M, London WB, Matthay KK, Nuchtern JG, von Schweinitz D, Simon T, Cohn SL, Pearson AD; INRG Task Force (2009) The International Neuroblastoma Risk Group (INRG) staging system: an INRG Task Force report. J Clin Oncol 27:298–303

    Article  PubMed  Google Scholar 

  • Noesel MM van, Versteeg R (2004) Pediatric neuroblastomas: genetic and epigenetic ‘danse macabre’. Gene 325: 1–15

    Article  PubMed  Google Scholar 

  • Otte JB, Aronson DC, Brown J et al. (2002) Liver transplantation for hepatoblastoma: results from the International Society of Pediatric Oncology (SIOP) study SIOPEL-1 and review of the world experience. Pediatr Blood Cancer 42: 74–83

    Article  Google Scholar 

  • Pfluger T, Schmied C, Porn U et al. (2003) Integrated imaging using MRI and 123I metaiodobenzylguanidine scintigraphy to improve sensitivity specificity in the diagnosis of pediatric neuroblastoma. Am J Roentgenol 181: 1115–1124

    Google Scholar 

  • Prasil P, Laberge JM, Bond M, Bernstein M, Pippi-Salle JL, Bernard C, Patenaude Y (2000) Management decisions in children with nephroblastomatosis. Med Pediatr Oncol 35: 429–432

    Article  CAS  PubMed  Google Scholar 

  • Pratt CB, Pappo AS (2002) Management of infrequent cancers of childhood. In: Pizzo PA, Poplack DG (eds) Principles and practice of pediatric oncology. Lippincott, Philadelphia, pp 1157–1158

    Google Scholar 

  • Reinhard H, Furtwängler R, Graf N (2007) Wilm’s tumor — update 2007. Urologe A 46:143–145

    Article  CAS  PubMed  Google Scholar 

  • Reinhard H, Schmidt A, Furtwängler R, Leuschner I, Rübe C, von Schweinitz D, Zoubek A, Niggi F, Graf N (2008) Outcome of relapses of nephroblastoma in patients registered in the SIOP/GPOH trials and studies. Oncol Rep 20:463–467

    PubMed  Google Scholar 

  • Roth R, Daum R (2001) Maligne viszerale Tumoren des Kindes. In: Siewert R (Hrsg) Onkologische Chirurgie, Bd II: Praxis der Viszeralchirurgie. Springer, Berlin Heidelberg New York Tokyo

    Google Scholar 

  • Sandberg DI, Bilsky MH, Kushner BH et al. (2003) Treatment of spinal involvement in neuroblastoma patients. Pediatr Neurosurg 39: 291–298

    Article  PubMed  Google Scholar 

  • Schnater JM, Köhler SE, Lamers WH, von Schweinitz D, Aronson DC (2003) Where do we stand with hepatoblastoma? A review. Cancer 98: 668–678

    Article  CAS  PubMed  Google Scholar 

  • Schwab M, Westermann F, Hero B, Berthold F (2003) Neuroblastoma: biology and molecular and chromosomal pathology. Lancet Oncol 4: 472–480

    Article  CAS  PubMed  Google Scholar 

  • Schweinitz D von (2004) Treatment of liver tumors in children. In: Clavien PA (ed) Malignant liver tumors: current and emerging therapies. Jones & Bartlett, Boston, pp 409–426

    Google Scholar 

  • Schweinitz D von (2006) Management of liver tumors in childhood. Sem Pediatr Surg 15:17–24

    Article  Google Scholar 

  • Schweinitz D von, Ure B (2009) Kinderchirurgie — Viszerale und allgemeine Chirurgie des Kindesalters. Springer, Berlin Heidelberg New York

    Google Scholar 

  • Schweinitz D von, Hero B, Berthold F (2002) The impact of surgical radicality on outcome in childhood neuroblastoma. Eur J Pediatr Surg 12: 402–409

    Article  Google Scholar 

  • Shimada H (2003) The international neuroblastoma pathology classification. Pathologica 95: 240–241

    CAS  PubMed  Google Scholar 

  • Shojaei-Brosseau T, Chompret A, Abel A (2004) Genetic epidemiology of neuroblastoma: a study of 426 cases at the

    Google Scholar 

  • Tomlinson GE, Finegold MJ (2002) Tumors of the liver. In: Pizzo PA, Poplack DG (eds) Principles and practice of pediatric oncology. Lippincott, Philadelphia, pp 847–864

    Google Scholar 

  • Tornoczky T, Kalman E, Kajtar PG et al. (2004) Large cell neuroblastoma: a distinct phenotype of neuroblastoma with aggressive clinical behavior. Cancer 100: 390–397

    Article  PubMed  Google Scholar 

  • Vujanic GM, Sandstedt B, Harms D, Kelsey A, Leuschner I, De Kraker J (2002) Revised International Society of Paediatric Oncology (SIOP) working classification of renal tumors of childhood. Med Pediatr Oncol 38: 79–82

    Article  PubMed  Google Scholar 

  • Weirich A, Leuschner I, Harms D et al. (2001) Clinical impact of histologic subtypes in localized non-anaplastic nephroblastoma teated according to the trial and study SIOP-9/GPOH. Ann Oncol 12: 311–319

    Article  CAS  PubMed  Google Scholar 

  • Weirich A, Ludwig R, Graf N et al. (2004) Survival in nephroblastoma treated according to the trial and study SIOP-9/GPOH with respect to relapse and morbidity. Ann Oncol: 808–820

    Google Scholar 

  • Zernikow B, Griessinger N, Fengler R (1999) Practice of pain control in paediatric oncology — recommendations of the quality-monitoring group of the German Society for Paediatric Oncology and Haematology (GPOH). Schmerz 13: 213–235

    Article  CAS  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Haunersches Kinderspital der Ludwig-Maximilians Universität München, Lindwurmstraße 4, 80337, München

    Univ.-Prof. Dr. med. D. von Schweinitz

  2. Klinik und Poliklinik für Kinderchirurgie der UniversitätLeipzig, Oststraße 21/25, 04317, Leipzig

    Prof. Dr. med. H. Till

Authors
  1. Univ.-Prof. Dr. med. D. von Schweinitz
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Prof. Dr. med. H. Till
    View author publications

    You can also search for this author in PubMed Google Scholar

Editor information

Editors and Affiliations

  1. Universitätsklinikum Heidelberg, Im Neuenheimer Feld 672, 69120, Heidelberg

    J. R. Siewert (Leitender Ärztlicher Direktor und Vorstandsvorsitzender) (Leitender Ärztlicher Direktor und Vorstandsvorsitzender)

  2. Zentrum für Operative Medizin I, Klinikum der Philipps-Universität, Baldinger Straße, 35043, Marburg

    Matthias Rothmund

  3. Universitätsklinik und Poliklinik, Medizinische Fakultät der RWTH, Pauwelsstraße 30, 52057, Aachen

    Volker Schumpelick

Rights and permissions

Reprints and permissions

Copyright information

© 2010 Springer-Verlag Berlin Heidelberg

About this chapter

Cite this chapter

von Schweinitz, D., Till, H. (2010). Maligne viszerale Tumoren des Kindes. In: Siewert, J.R., Rothmund, M., Schumpelick, V. (eds) Praxis der Viszeralchirurgie Onkologische Chirurgie. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-03808-2_53

Download citation

  • DOI: https://doi.org/10.1007/978-3-642-03808-2_53

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-03807-5

  • Online ISBN: 978-3-642-03808-2

  • eBook Packages: Medicine (German Language)

Publish with us

Policies and ethics

Search

Navigation