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Using Existing Biomedical Resources to Detect and Ground Terms in Biomedical Literature

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Artificial Intelligence in Medicine (AIME 2009)

Part of the book series: Lecture Notes in Computer Science ((LNAI,volume 5651))

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Abstract

We present an approach towards the automatic detection of names of proteins, genes, species, etc. in biomedical literature and their grounding to widely accepted identifiers. The annotation is based on a large term list that contains the common expression of the terms, a normalization step that matches the terms with their actual representation in the texts, and a disambiguation step that resolves the ambiguity of matched terms. We describe various characteristics of the terms found in existing term resources and of the terms that are used in biomedical texts. We evaluate our results against a corpus of manually annotated protein mentions and achieve a precision of 57% and recall of 72%.

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References

  1. Hakenberg, J.: What’s in a gene name? Automated refinement of gene name dictionaries. In: Proceedings of BioNLP 2007: Biological, Translational, and Clinical Language Processing; Prague, Czech Republic (2007)

    Google Scholar 

  2. Kappeler, T., Kaljurand, K., Rinaldi, F.: TX Task: Automatic Detection of Focus Organisms in Biomedical Publications. In: BioNLP 2009, NAACL/HLT, Boulder, Colorado, June 4–5 (2009)

    Google Scholar 

  3. Leitner, F., Krallinger, M., Rodriguez-Penagos, C., Hakenberg, J., Plake, C., Kuo, C.-J., Hsu, C.-N., Tsai, R.T.-H., Hung, H.-C., Lau, W.W., Johnson, C.A., Saetre, R., Yoshida, K., Chen, Y.H., Kim, S., Shin, S.-Y., Zhang, B.-T., Baumgartner, W.A., Hunter, L., Haddow, B., Matthews, M., Wang, X., Ruch, P., Ehrler, F., Ozgur, A., Erkan, G., Radev, D.R., Krauthammer, M., Luong, T., Hoffmann, R.: Introducing meta-services for biomedical information extraction. Genome Biology 9(suppl. 2), S6 (2008)

    Article  Google Scholar 

  4. Liu, H., Hu, Z.-Z., Zhang, J., Wu, C.: BioThesaurus: a web-based thesaurus of protein and gene names. Bioinformatics 22(1), 103–105 (2006)

    Article  CAS  PubMed  Google Scholar 

  5. Mathivanan, S., Periaswamy, B., Gandhi, T.K.B., Kandasamy, K., Suresh, S., Mohmood, R., Ramachandra, Y.L., Pandey, A.: An evaluation of human protein-protein interaction data in the public domain. BMC Bioinformatics 7(suppl. 5), 19 (2006)

    Article  Google Scholar 

  6. Morgan, A.A., Lu, Z., Wang, X., Cohen, A.M., Fluck, J., Ruch, P., Divoli, A., Fundel, K., Leaman, R., Hakenberg, J., Sun, C.: Overview of BioCreative II gene normalization. Genome Biology 9(suppl. 2), S3 (2008)

    Article  Google Scholar 

  7. Rinaldi, F., Kappeler, T., Kaljurand, K., Schneider, G., Klenner, M., Clematide, S., Hess, M., von Allmen, J.-M., Parisot, P., Romacker, M., Vachon, T.: OntoGene in BioCreative II. Genome Biology 9(suppl. 2), S13 (2008)

    Article  Google Scholar 

  8. Sarntivijai, S., Ade, A.S., Athey, B.D., States, D.J.: A bioinformatics analysis of the cell line nomenclature. Bioinformatics 24(23), 2760–2766 (2008)

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  9. Tanabe, L., John Wilbur, W.: Tagging gene and protein names in biomedical text. Bioinformatics 18(8), 1124–1132 (2002)

    Article  CAS  PubMed  Google Scholar 

  10. Wang, X., Matthews, M.: Distinguishing the species of biomedical named entities for term identification. BMC Bioinformatics 9(suppl. 11), S6 (2008)

    Article  CAS  Google Scholar 

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© 2009 Springer-Verlag Berlin Heidelberg

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Kaljurand, K., Rinaldi, F., Kappeler, T., Schneider, G. (2009). Using Existing Biomedical Resources to Detect and Ground Terms in Biomedical Literature. In: Combi, C., Shahar, Y., Abu-Hanna, A. (eds) Artificial Intelligence in Medicine. AIME 2009. Lecture Notes in Computer Science(), vol 5651. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-02976-9_32

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  • DOI: https://doi.org/10.1007/978-3-642-02976-9_32

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-02975-2

  • Online ISBN: 978-3-642-02976-9

  • eBook Packages: Computer ScienceComputer Science (R0)

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