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Sordaria macrospora, a Model System for Fungal Development

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Physiology and Genetics

Part of the book series: The Mycota ((MYCOTA,volume 15))

Abstract

The homothallic ascomycete Sordaria macrospora has a long-standing history as a classic genetic model system for conventional tetrad analysis. Further, it serves as a model organism to investigate the formation of fruiting bodies that are generated during the sexual life cycle of this filamentous fungus. The application of several molecular tools, such as DNA-mediated transformation, site-specific recombination or functional genomics to this filamentous fungus makes it an ideal experimental system to uncover the details of multicellular development. The rapid and inexpensive genetic analysis of developmental mutants with distinct and defined morphological defects, together with fluorescence microscopy of recombinant strains carrying GPF-tagged developmental proteins should further unravel the spatio-temporal network of regulatory factors. The sum of these investigations will contribute to our understanding of multicellular differentiation processes in eukaryotic model organisms

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Acknowledgements.

We thank Ms. Gabriele Frenßen-Schenkel for artwork, Ms. Melanie Mees for typing the manuscript and Dr. Sandra Masloff for preparing scanning electron microscopic images from developmental mutants. The work of the authors is substantially supported by funding from the Deutsche Forschungsgemeinschaft (Bonn-Bad Godesberg, Germany).

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  1. Nicole Nolting

    Present address: Abteilung Genetik eukaryotischer Mikroorganismen, Institut für Mikrobiologie und Genetik, Georg-August-Universität Göttingen, Grisebachstrasse 8, 37077, Göttingen, Germany

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  1. Lehrstuhl für Allgemeine und Molekulare Botanik, Fakultät für Biologie, Ruhr-Universität Bochum, Universitätsstrasse 150, 44780, Bochum, Germany

    Ulrich Kück, Minou Nowrousian & Ines Engh

  2. Abteilung Genetik eukaryotischer Mikroorganismen, Institut für Mikrobiologie und Genetik, Georg-August-Universität Göttingen, Grisebachstrasse 8, 37077, Göttingen, Germany

    Stefanie Pöggeler

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Correspondence to Ulrich Kück .

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Kück, U., Pöggeler, S., Nowrousian, M., Nolting, N., Engh, I. (2009). Sordaria macrospora, a Model System for Fungal Development. In: Anke, T., Weber, D. (eds) Physiology and Genetics. The Mycota, vol 15. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-00286-1_2

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