Abstract
Image based quantitative stratification of the Left Ventricles (LV) across a population helps in unraveling the structure-function symbiosis of the heart. An unbiased, reference less grouping scheme that automatically determines the number of clusters and a physioanatomically relevant strategy that aligns the intra cluster LV shapes would enable the robust construction of pathology stratified cardiac atlas. This paper achieves this hitherto elusive stratification and alignment by adapting the conventional strategies routinely followed by clinicians. The individual LV shape models (N=127) are independently oriented to an "attitudinally consistent orientation" that captures the physioanatomic variations of the LV morphology. Affinity propagation technique based on the automatically identified inter-LV_landmark distances is used to group the LV shapes. The proposed algorithm is computationally efficient and, if the inter cluster variations are linked to pathology, could provide a clinically relevant cardiac atlas.
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References
Bhatia, K.K., et al.: Consistent group-wise non-rigid registration for atlas construction. In: Proc. IEEE Symposium on Biomedical Imaging (ISBI), pp. 908–911 (2004)
De Craene, M., et al.: Multi-subject registration for unbiased Statistical Atlas Construction. In: Barillot, C., Haynor, D.R., Hellier, P. (eds.) MICCAI 2004. LNCS, vol. 3216, pp. 655–662. Springer, Heidelberg (2004)
Zollie, L., et al.: Efficient population registration of 3D data. In: Liu, Y., Jiang, T., Zhang, C. (eds.) CVBIA 2005. LNCS, vol. 3765, pp. 291–301. Springer, Heidelberg (2005)
McAlpine, W.A.: Heart and Coronary Arteries. An anatomical atlas for Clinical Diagnosis, Radiological Investigation, and Surgical Treatment. Springer, Berlin (1995)
Edwards, L.: The Vortex of Life. Floris Books (1993)
Gould, K.L., et al.: Analysis of wall dynamics and directional components of left ventricular contraction in man. Am. J. Cardiol. 38, 322 (1976)
Mahesh, M., Cody, D.D.: Physics of Cardiac imaging with multiple-row detector CT. Radiographics 27, 1495–1509 (2007)
Frey, B., Dueck, D.: Clustering by Passing Messages between Data Points. Science 315, 972 (2007)
Gagvani, N., Silver, D.: Parameter controlled skeletonization of three dimensional objects. Technical Report CAIP-TR-216, Rutgers State University of New Jersey (1997)
Moorman, A., et al.: Development of the heart: formation of the cardiac chambers and arterial trunks. Heart 89, 806–814 (2003)
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Srinivasan, R., Shriram, K.S., Suryanarayanan, S. (2008). Unbiased Stratification of Left Ventricles. In: Metaxas, D., Axel, L., Fichtinger, G., Székely, G. (eds) Medical Image Computing and Computer-Assisted Intervention – MICCAI 2008. MICCAI 2008. Lecture Notes in Computer Science, vol 5241. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-540-85988-8_66
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DOI: https://doi.org/10.1007/978-3-540-85988-8_66
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