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Sunscreens

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Non-Surgical Treatment of Keratinocyte Skin Cancer

The biological efficacy (erythema action) of the radiation is dependent on wavelength. The unit SED (standard erythema dose) is a direct measure of the erythema action of radiation. The skin by itself absorbs UV radiation depending on the thickness of stratum corneum and the degree of pigmentation. When testing SPF of a sunscreen in humans 2 mg/cm2 is applied, in real life much less sunscreen is used 0.5 mg/cm2. It has been suggested that the protection is reduced exponentially when a thinner layer is used. The number of sunburn cells, cutaneous DNA damage, conversion of urocanic acid, and immu-nosuppression are diminished by sunscreen use. Human studies have indicated that the number of actinic keratoses as well as squamous cell carcinomas can be reduced if sunscreens are used regularly.

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Authors and Affiliations

  1. Department of Dermatol, Bispebjerg Hospital, University of Copenhagen, D42, Bispebjerg Bakke 23, Copenhagen NV, DK-2400, Denmark

    Hans Christian Wulf

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  1. Hans Christian Wulf
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Correspondence to Hans Christian Wulf .

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Editors and Affiliations

  1. Dept. of Dermatology, University of Copenhagen, Roskilde Hospital, Køgevej 7-13, Roskilde, 4000, Denmark

    Gregor B. E. Jemec

  2. Dept. Dermatology & Allergology, University of Szeged, Korányi Fasor 6, Szeged, 6720, Hungary

    Lajos Kemeny

  3. Dept. Dermatology, Marshfield Clinic, 1000 N. Oak Ave., Marshfield, WI, 54449, USA

    Donald Miech

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Wulf, H.C. (2010). Sunscreens. In: Jemec, G.B.E., Kemeny, L., Miech, D. (eds) Non-Surgical Treatment of Keratinocyte Skin Cancer. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-540-79341-0_21

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  • DOI: https://doi.org/10.1007/978-3-540-79341-0_21

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-79340-3

  • Online ISBN: 978-3-540-79341-0

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