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Henoch-Schoenlein Purpura

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Pediatric Nephrology

Abstract

Heberden was the first to report, the beginning of 1800, the observation of one child presenting with petechial hemorrhages on lower limbs, joint, and abdominal pain, bloody stools and gross hematuria (1). The syndrome was named after the description by Schoenlein of the clinical entity characterized by purpura and joint pain (2) and by Henoch of the frequent association of gastrointestinal symptoms and kidney involvement (3). Henoch-Schoenlein purpura (HSP) is a small vessel vasculitis with multiorgan involvement including skin, gastro-intestinal tract, joints, and kidneys with variable clinical expression (4, 5). The past ambiguous definitions of hypersensitivity angiitis, anaphylactoid purpura or streptococcal rheumatic peliosis indicate the frequent clinical relationship between HSP and either allergy or infections.

*Corresponding author.

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Authors and Affiliations

  1. School of Post-Graduated Nephrology, Post-Graduated School of Paediatrics, University of Turin, Italy; Nephrology, Dialysis and Transplantation Unit, Regina Margherita Children’s University Hospital, Turin, Torino, Italy

    Rosanna Coppo

  2. University Research Doctorate in Experimental Paediatrics, University of Turin; Vice-Chief Nephrology, Dialysis and Transplantation Unit, Regina Margherita Children’s University Hospital, Turin, Italy

    Alessandro Amore

Authors
  1. Rosanna Coppo
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  2. Alessandro Amore
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Editors and Affiliations

  1. Medical College of Wisconsin, Wisconsin, USA

    Ellis Avner (Director, Children's Research Institute, CHHS, Associate Dean for Research, Professor of Pediatrics and Physiology) (Director, Children's Research Institute, CHHS, Associate Dean for Research, Professor of Pediatrics and Physiology)

  2. Harvard Medical School, Children's Hospital Boston, 300 Longwood Avenue, Boston, Massachusetts, 02115, USA

    William Harmon (Professor of Pediatrics, Director, Pediatric Nephrology) (Professor of Pediatrics, Director, Pediatric Nephrology)

  3. Service de Néphrologie Pédiatrique Centre de référence des Maladies Rénales Héréditaires de l'Enfant et de l'Adulte (MARHEA), Hôpital Necker‐Enfants Malades, 149, rue de Sèvres, 75743, Paris Cedex 15, France

    Patrick Niaudet

  4. Department of Pediatrics Wakayama Medical University, Wakayama Medical University Hospital, 641–8510811–1, Kimiidera, Wakayama City, Japan

    Norishige Yoshikawa (Professor and Chair Pediatrician‐in‐Chief) (Professor and Chair Pediatrician‐in‐Chief)

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© 2009 Springer-Verlag Berlin Heidelberg

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Coppo, R., Amore, A. (2009). Henoch-Schoenlein Purpura. In: Avner, E., Harmon, W., Niaudet, P., Yoshikawa, N. (eds) Pediatric Nephrology. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-540-76341-3_46

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  • DOI: https://doi.org/10.1007/978-3-540-76341-3_46

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-76327-7

  • Online ISBN: 978-3-540-76341-3

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