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West Nile Virus

  • Chapter
Intraocular Inflammation

Abstract

West Nile virus (WNV) infection is a worldwide zoonosis due to a Flavivirus transmitted by a mosquito vector. Most human infections are subclinical or manifest as febrile illness, but a small proportion of patients may develop severe neurologic disease (meningoencephalitis), frequently associated with advanced age and diabetes. A bilateral multifocal chorioretinitis is the most common ocular manifestation of WNV infection, occurring in nearly 80 % of patients with severe systemic disease. Other ophthalmologic findings include anterior uveitis, retinal vasculitis, optic neuritis, and congenital chorioretinal scarring. WNV-associated ocular involvement usually has a self-limited course. There is no effective antiviral therapy against WNV infection and prevention is the mainstay of WNV infection control.

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Author information

Authors and Affiliations

  1. Department of Ophthalmology, Fattouma Bourguiba University Hospital, Monastir, 5019, Tunisia

    Moncef Khairallah MD, Salim Ben Yahia MD & Rim Kahloun MD

Authors
  1. Moncef Khairallah MD
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  2. Salim Ben Yahia MD
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  3. Rim Kahloun MD
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Corresponding authors

Correspondence to Moncef Khairallah MD , Salim Ben Yahia MD or Rim Kahloun MD .

Editor information

Editors and Affiliations

  1. Centre of Ophthalmology, University of Tuebingen, Tuebingen, Germany

    Manfred Zierhut

  2. Biomedical Research Centre, Institute of Ophthalmology, Moorfields Eyes Hospital, Department of Medical Retina, UCL, London, United Kingdom

    Carlos Pavesio

  3. School of Medicine, Department of Ophthalmology, Hokkaido University Graduate, Sapporo, Hokkaido, Japan

    Shigeaki Ohno

  4. University of Belo Horizonte, Belo Horizonte, Brazil

    Fernando Orefice

  5. USC Eye Institute, University of Southern California, Los Angeles, California, USA

    Narsing A. Rao

1 Electronic Supplementary Material

Below is the link to the electronic supplementary material.

Case Report 27

West Nile virus infection (PPT 1985 kb)

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Khairallah, M., Ben Yahia, S., Kahloun, R. (2016). West Nile Virus. In: Zierhut, M., Pavesio, C., Ohno, S., Orefice, F., Rao, N. (eds) Intraocular Inflammation. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-540-75387-2_118

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  • DOI: https://doi.org/10.1007/978-3-540-75387-2_118

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-75385-8

  • Online ISBN: 978-3-540-75387-2

  • eBook Packages: MedicineMedicine (R0)

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