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Assembly and Traffic of Small Nuclear RNPs

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RNA Trafficking and Nuclear Structure Dynamics

Part of the book series: Progress in Molecular and Subcellular Biology ((PMSB,volume 35))

Eukaryotic cells contain many types of ribonucleoproteins (RNPs) which are complexes formed by RNA molecules associated with proteins. The majority of these RNPs are in the nucleus and can be classified in two groups, the small nuclear RNPs (snRNPs) that function in the maturation of messenger RNAs, and the small nucleolar RNPs that reside in the cell nucleolus and are required for maturation of ribosomal RNAs. Although both types of RNPs function in two different fundamental processes, progress made during the last few years shows that their assembly requires similar protein components. This review focuses on the factors and mechanisms governing snRNPs and snoRNPs biogenesis as well as on the mechanisms implicated in the sorting of these RNPs to their intracellular destinations.

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Authors and Affiliations

  1. Institut de Génétique Moléculaire de Montpellier, 1919 route de Mende, 34293, Montpellier, France

    Edouard Bertrand & Rémy Bordonné

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  1. Edouard Bertrand
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  2. Rémy Bordonné
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  1. Institute of Molecular Genetics of Montpellier, 1919 Route de Mende, 5051, 34293, Montpellier, France

    Philippe Jeanteur

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© 2008 Springer-Verlag Berlin Heidelberg

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Bertrand, E., Bordonné, R. (2008). Assembly and Traffic of Small Nuclear RNPs. In: Jeanteur, P. (eds) RNA Trafficking and Nuclear Structure Dynamics. Progress in Molecular and Subcellular Biology, vol 35. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-540-74266-1_4

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  • DOI: https://doi.org/10.1007/978-3-540-74266-1_4

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-74265-4

  • Online ISBN: 978-3-540-74266-1

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