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DBS for Persistent Non-Cancer Pain

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Textbook of Stereotactic and Functional Neurosurgery

Abstract

The use of electrical stimulation to treat pain dates back from the 1950s, when Heath [1,2] and Pool [3] reported analgesic effects in patients receiving stimulation in the septal region. Despite of these earlier trials, most of the pioneering studies that led to the development of deep brain stimulation (DBS) as currently employed in the clinical practice took place in the early 1970s. Electrical stimulation of the thalamus and internal capsule was initially developed by Mazars et al. [4–7], White and Sweet [8], Hosobuchi et al. [9,10], Adams et al. [11], and Fields et al. [12]. A few years later, Richardson and Akil [13–15] and Hosobuchi et al. [16] described the first clinical results with periaqueductal (PAG)/periventricular gray matter (PVG) stimulation.

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  1. C. Hamani
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  2. D. Fontaine
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  3. A. Lozano
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Editors and Affiliations

  1. Canadian Research Chair in Neuroscience (Tier 1), 399 Bathurst St. WW 4-447, Toronto, Ontario, M5T 2S8, Canada

    Andres M. Lozano (Professor of Surgery and RR Tasker Chair in Functional Neurosurgery University of Toronto Senior Scientist, Toronto Western Research Institute President, World Society for Stereotactic and Functional Neurosurgery) (Professor of Surgery and RR Tasker Chair in Functional Neurosurgery University of Toronto Senior Scientist, Toronto Western Research Institute President, World Society for Stereotactic and Functional Neurosurgery)

  2. Houston Stereotactic Concepts, Inc., 2260 West Holcombe Boulevard Suite 309, Houston, Texas, 77030, USA

    Philip L. Gildenberg

  3. University of Toronto, 399 Bathurst St. WW 4-447, Toronto, Ontario, M5T 2S8, Canada

    Ronald R. Tasker

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Hamani, C., Fontaine, D., Lozano, A. (2009). DBS for Persistent Non-Cancer Pain. In: Lozano, A.M., Gildenberg, P.L., Tasker, R.R. (eds) Textbook of Stereotactic and Functional Neurosurgery. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-540-69960-6_131

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  • DOI: https://doi.org/10.1007/978-3-540-69960-6_131

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