Abstract
Osteoarthritis (OA) and osteoporosis (OP) are the two most common musculoskeletal diseases in the elder population. This study was designed to (a) compare the mechanical properties of trabecular bone of femoral head in OA and OP patients, (b) investigate the effect of the geometry and material properties changes on trabecular tissue by finite element analysis, and (c) study the influence of mechanical property changes of the subchondral plate, the femoral head, and the femoral neck on stress distribution at the articular cartilage from the patients with OA and OP using finite element analysis (FEA). Our analysis showed that parameter of the trabecular number (density and volume) were sensitive for bone strength. The material properties were sensitive for bone strength compared with index parameters. Stronger material properties resulted in a low proportion of elements exceeding yield strain, suggesting stronger trabecular bone tissue. The results revealed that in OA patients, bone density was much higher than in OP patients, and supported the observation that OA might be more likely to occur in those people with stiffer bone in the proximal femur.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
References
Anderson DD, Brown TD, Radin EL. The influence of basal cartilage calcification on dynamic juxtaarticular stress transmission (1993) Clin Orthop Relat Res 286:298–307
Bader DL, Kempson GE (1994) The short-term compressive properties of adult human articular cartilage. Biomed Mater Eng 4:245–256
Brown TD (1981) Mechanical characteristics of bone in femoral capital aseptic necrosis. Clin Orthop 156:240–247
Carter DR, Schwab GH, Spengler DM (1980) Tensile fracture of cancellous bone. Acta Orthop Scand 51:733–741
Cooper C, Cook PL, Osmond C, Fisher L, Cawley MID (1991) Osteoarthritis of the hip and osteoporosis of the proximal femur. Ann Rheum Dis 50:540–542
Dequeker J, Johnell O (1995) Osteoathritis protects against femoral neck fracture: the MEDOS study experience. Bone 14: S51–S56
Dequeker J, Mokassa L, Aerssens J (1995) Bone density and osteoarthritis. J Rheum 22(Suppl 43):98–100
Dretakis EK, Steriopoulos KA, Kontakis GM (1998) Cervical hip fractures do not occur in arthrotic joints. Acta Orthop Scand 69:384–386
Knauss P (1981) Material properties and strength behaviour of spongy bone tissue at the coxal human femur. Biomed Technol 26:200–210
Li B, Aspden RM (1997) Mechanical and material properties of the subchondral bone plate from the femoral head of patients with osteoarthritis or osteoporosis. Ann Rheum Dis 56:247–254
Li X, Haut RC, Altiero NJ (1995) An analytical model to study blunt impact response of the rabbit P-F joint. J Biomech Eng 117:485–491
Moore RJ, Fazzalari NL, Manthey BA, Vernon-Roberts B (1994) The relationship between head-neck-shaft angle, calcar width, articular cartilage thickness and bone volume in cartilage of the hip thickness and bone volume in arthrosis of the hip. Br J Rheum 33:432–436
Radin EL, Rose RM (1986) The role of subchondral bone in the initiation and progression of cartilage damage. Clin Orthop Relat Res 213:34–40
Rietbergen BV, Weinans H, Huiskes R, Odgaardt A (1995) A new method to determine trabecular bone elastic properties and loading using micromechanical finite element models. J Biomech 28:69–81
Schnitzler CM, Mesquita JM, Wane L (1992) Bone histomorphometry of the iliac crest, and spinal fracture prevalence in atrophic and hypertrophic osteoarthritis of the hip. Osteoporosis Int 2:186–194
Shepherd DE, Seedhom BB (1999) Thickness of human articular cartilage in joints of the lower limb. Ann Rheum Dis 58:27–34
Ueo T, Tsutsumi S, Yamamuro T, Okumura H, Shimizu A, Nakamura T (1985) Biomechanical aspects of the development of aseptic necrosis of the femoral head. Arch Orthop Trauma Surg 104:145–149
Wand JS, Hill ID, Reeve J (1992) Coxarthrosis and femoral neck fracture. Clin Orthop 278:88–94
Wei HW, Sun SS, Jao SH, Yeh CR, Cheng CK (2005) The influence of mechanical properties of subchondral plate, femoral head and neck on dynamic stress distribution of the articular cartilage. Med Eng Phys 27:295–304
Werner HJ, Martin H, Behrend D, Schmitz KP, Schober HC (1996) The loss of stiffness as osteoporosis progresses. Med Eng Phys 18:601–606
Wirtz DC, Schiers N, Pandorf T, Radermacher K, Weichert D, Forst R (2000) Critical evaluation of known bone material properties to realize anisotropic FE-simulation of the proximal femur. J Biomech 33:1325–1330
Author information
Authors and Affiliations
Corresponding author
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2007 Springer-Verlag Berlin Heidelberg
About this chapter
Cite this chapter
Cheng, CK., Lai, YS., Sun, SS., Shen, HW., Yang, CT., Wei, HW. (2007). Mechanical Property of Trabecular Bone of the Femoral Heads from Osteoarthritis and Osteoporosis Patients. In: Qin, L., Genant, H.K., Griffith, J.F., Leung, K.S. (eds) Advanced Bioimaging Technologies in Assessment of the Quality of Bone and Scaffold Materials. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-540-45456-4_43
Download citation
DOI: https://doi.org/10.1007/978-3-540-45456-4_43
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-540-45454-0
Online ISBN: 978-3-540-45456-4
eBook Packages: MedicineMedicine (R0)