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Nuclear Export of Messenger RNA

  • Chapter
Nuclear Transport

Part of the book series: Results and Problems in Cell Differentiation ((RESULTS,volume 35))

Abstract

Messenger RNAs (mRNAs) exist in the cell in dynamic association with multiple distinct proteins. The mRNA export cargo is therefore a ribonucleoprotein particle (mRNP). The most striking example of this are the Balbiani ring (BR) mRNPs of Chironomus tentans which are composed of an RNA molecule of 35–40 kb in length associated with about 500 protein molecules (Mehlin et al. 1992; reviewed by Daneholt 1997). Among the most abundant RNA-binding proteins found associated to heterogeneous (in size) nuclear mRNPs are the hnRNP proteins. There are about 20 different hnRNP proteins in higher eukaryotes (hnRNP A to hnRNP U, reviewed by Dreyfuss et al. 1993).

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  1. EMBL, Meyerhofstrasse 1, 69117, Heidelberg, Germany

    Elisa Izaurralde

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  1. Department of Molecular & Cell Biology, University of California, Berkeley, 94720-3200, Berkeley, CA, USA

    Karsten Weis

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© 2002 Springer-Verlag Berlin Heidelberg 2002

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Izaurralde, E. (2002). Nuclear Export of Messenger RNA. In: Weis, K. (eds) Nuclear Transport. Results and Problems in Cell Differentiation, vol 35. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-540-44603-3_7

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  • DOI: https://doi.org/10.1007/978-3-540-44603-3_7

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