Abstract
Mechanical models for soft human organs are necessary for a variety of medical applications, such as surgical planning, virtual reality surgery simulators, and for diagnostic purposes. An adequate quantitative description of the mechanical behaviour of human organs requires high quality experimental data to be acquired and analyzed. We present a novel technique for the acquisition of such data from soft tissues and its post processing to determine some parameters of the tissue’s mechanical properties. A small tube is applied to the target organ and a weak vacuum is generated inside the tube according to a predefined pressure history. A video camera grabs images of the deformation profile of the aspirated tissue, and a pressure sensor measures the correspondent vacuum level. The images are processed and used to inform the fitting of uniaxial and continuum mechanics models. Whilst the aspiration test device has been designed to fulfill the requirements for in-vivo applications, for measurements obtained during open surgery, initial experiments performed on human cadaveric tissues demonstrate the ability to both differentiate between different organs and also between normal and diseased organs on the basis of the derived mechanical properties.
Chapter PDF
Similar content being viewed by others
Keywords
- Relaxation Modulus
- Continuum Mechanic Model
- Aspiration Experiment
- Strain Potential Energy
- Soft Human Tissue
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.
References
Avis, N.J.: Virtual Environment Technologies. Journal of Minimally Invasive Therapy and Allied Technologies 9(5), 333–340 (2000)
Szekely, G., Brechbüler, C., Hutter, R., Rhomberg, A., Schmidt, P.: Modelling of soft tissue deformation for laparoscopic surgery simulation. In: Wells, W.M., Colchester, A.C.F., Delp, S.L. (eds.) MICCAI 1998. LNCS, vol. 1496, pp. 550–561. Springer, Heidelberg (1998)
Brett, P.N., Fraser, C.A., Henningam, M., Griffiths, M.V., Kamel, Y.: Automatic surgical tools for penetrating flexible tissues. IEEE Eng. Medicine and Biology, 264–270 (1995)
Burdea, G.: Force and Touch Feedback for Virtual Reality. Wiley, New York (1996)
Vuskovic, V.: Device for in-vivo measurement of mechanical properties of internal human soft tissues. Diss., ETH No. 14222 (2001)
Kauer, M.: Characterization of soft tissues with aspiration experiments. Diss., ETH No. 14233 (2001)
Kalanovic, D., Ottensmeyer, M.P., Gross, J., Gerhardt, B., Dawson, S.: Independent testing of Soft tissue viscoelasticity using indention and rotary shear deformation, pp. 137–143. Medicine Meets Virtual Reality IOS Press, Amsterdam (2003)
Fung, Y.C.: Elasticity of soft tissues in simple elongation. Am. J. Physiol. 213, 1532 (1967)
Ottensmeyer, M.P., Salisbury, J.K.: In Vivo Data Acquisition Instrument For Solid Organ Mechanical Property Measurement. In: Niessen, W.J., Viergever, M.A. (eds.) MICCAI 2001. LNCS, vol. 2208, pp. 975–982. Springer, Heidelberg (2001)
Carter, F.J., Frank, T.G., Davies, M.D., Cuschieri, A.: Measurement and modelling of the compliance of human and porcine organs. Medical Image Analysis 5(4), 231–236 (2001)
Miller, K., Chinzei, K., Orssengo, G., Bednarz, P.: Mechanical properties of brain tissue in vivo: experiment and computer simulation. J. of Biomech. 33/11, 1369–1376 (2000)
Silver-Thorn, M.B.: In vivo indentation of lower extremity limb soft tissues. IEEE Transactions on Rehabilitation Enginnering 7(33/11), 269–277 (1999)
Aoki, T., Ohashi, T., Matsumoto, T., Sato, M.: The pipette aspiration applied to the local stiffness measurement of soft tissues. Ann. of Biom. Eng. 25, 581–587 (1997)
Fung, Y.C.: Mechanical properties of living tissues. Springer, Heidelberg (1993)
Viidik, A.: Functional properties of collagenous tissues. Internal Review of Connective Tissue Research 6, 127–215 (1973)
Yeoh, O.H.: Some forms of the strain energy function for rubber. Rubber Chemistry and Technology 66, 754–771 (1993)
Hibbit, Karlsson, Sorensen: ABAQUS theory manual. Version 6.2 (2001)
Nelder, J.A., Mead, R.: A simplex method for function minimization. Computer Journal 7, 308–313 (1965)
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2003 Springer-Verlag Berlin Heidelberg
About this paper
Cite this paper
Nava, A., Mazza, E., Kleinermann, F., Avis, N.J., McClure, J. (2003). Determination of the Mechanical Properties of Soft Human Tissues through Aspiration Experiments. In: Ellis, R.E., Peters, T.M. (eds) Medical Image Computing and Computer-Assisted Intervention - MICCAI 2003. MICCAI 2003. Lecture Notes in Computer Science, vol 2878. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-540-39899-8_28
Download citation
DOI: https://doi.org/10.1007/978-3-540-39899-8_28
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-540-20462-6
Online ISBN: 978-3-540-39899-8
eBook Packages: Springer Book Archive