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The Molecular Biology of Photodynamic Action

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Lasers in Photomedicine and Photobiology

Part of the book series: Springer Series in Optical Sciences ((SSOS,volume 22))

Abstract

According to BLUM [1], the expression photodynamic action indicates those photosensitized reactions, induced in biological systems by visible light, in which molecular oxygen is consumed. This operational definition is still valid, although a few photosensitizers, which are widely diffused in living organisms e.g., flavins, ketones, psoralens), may not require oxygen for their action. On this basis, photodynamic action is promoted only by light wavelengths greater than about 320 nm; more energetic wavelengths would be directly absorbed by cell constituents, especially proteins and nucleic acids, which might then undergo photochemical modifications even in the absence of photosensitizing compounds [2]. Thus, photodynamic action is induced by the primary interaction of the incident light with the photosensitizer molecule.

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© 1980 Springer-Verlag Berlin Heidelberg

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Jori, G. (1980). The Molecular Biology of Photodynamic Action. In: Pratesi, R., Sacchi, C.A. (eds) Lasers in Photomedicine and Photobiology. Springer Series in Optical Sciences, vol 22. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-540-38270-6_6

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  • DOI: https://doi.org/10.1007/978-3-540-38270-6_6

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-662-13499-3

  • Online ISBN: 978-3-540-38270-6

  • eBook Packages: Springer Book Archive

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