Abstract
Scope of this work is to investigate for which type of radiopharmaceuticals is particularly important to perform patient dosimetry using realistic reference voxel models (a male and a female) instead of the MIRD-type model. For the present work, calculations for patient doses were performed using biokinetic data and the SAFs of the voxel models. A comparison in relation to organ and effective dose estimates by the two methods was done for radiopharmaceuticals chosen for their widely differing biodistributions. By comparing directly the organ doses resulting from the MIRD-type phantom to those from the voxel ones, both types representing the average patient, it can be studied for which types of radiopharmaceuticals a change-over to voxel-based SAFs is essential. Moreover, gender specific differences were studied.
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© 2007 International Federation for Medical and Biological Engineering
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Petoussi-Henss, N., Zankl, M., Hoeschen, C., Nosske, D. (2007). Voxel or MIRD-type model: a sensitivity study relevant to nuclear medicine. In: Magjarevic, R., Nagel, J.H. (eds) World Congress on Medical Physics and Biomedical Engineering 2006. IFMBE Proceedings, vol 14. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-540-36841-0_519
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DOI: https://doi.org/10.1007/978-3-540-36841-0_519
Publisher Name: Springer, Berlin, Heidelberg
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