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Simple Pattern-only Heuristics Lead to Fast Subgraph Matching Strategies on Very Large Networks

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Practical Applications of Computational Biology and Bioinformatics, 12th International Conference (PACBB2018 2018)

Abstract

A wide range of biomedical applications entails solving the subgraph isomorphism problem, i.e. finding all the possible subgraphs of a target graph that are structurally equivalent to an input pattern graph. Targets may be very large and complex structures compared to patterns. Methods that address this NP-complete problem use heuristics. Their performance in both time and quality depends on a few subtleties of those heuristics. This paper compares the performance of state-of-the-art algorithms for subgraph isomorphism on small, medium and very large graphs. Results show that heuristics based on pattern graphs alone prove to be the most efficient, an unexpected result.

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Notes

  1. 1.

    http://www.internationalgenome.org/.

  2. 2.

    http://www.encodeproject.org.

  3. 3.

    https://cancergenome.nih.gov/.

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Correspondence to Rosalba Giugno .

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Aparo, A. et al. (2019). Simple Pattern-only Heuristics Lead to Fast Subgraph Matching Strategies on Very Large Networks. In: Fdez-Riverola, F., Mohamad, M., Rocha, M., De Paz, J., González, P. (eds) Practical Applications of Computational Biology and Bioinformatics, 12th International Conference. PACBB2018 2018. Advances in Intelligent Systems and Computing, vol 803. Springer, Cham. https://doi.org/10.1007/978-3-319-98702-6_16

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