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Hepatic Abscess

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Emergency General Surgery

Abstract

Hepatic abscesses are characterized by a suppurative fluid collection of invasive and multiplying microorganisms within the liver. The primary organisms involved are bacteria accounting for approximately 80% of abscess, followed by parasites (amoebae), and rarely fungi. Hepatic abscesses (HA) are rare, with an incidence ranging between 1/100000 and 86/100000. However, there is some indication in recent studies that the incidence of HA is increasing. Due to advances in diagnosis and management, the mortality for HA is decreasing. The first review of pyogenic abscesses (PA) by Ochsner (1938) reported a mortality rate of 77%. With the advent of percutaneous treatment in the 1980s, mortality rates fell to 24–50%. Modern case series report mortality rates between 2.5% and 19%. The population of patients affected by HA is shifting as well. The average age at diagnosis and number of comorbidities are increasing, and the etiologies are shifting from primarily infectious to biliary and cryptogenic etiologies.

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Brito, A., Kobayashi, L. (2019). Hepatic Abscess. In: Brown, C., Inaba, K., Martin, M., Salim, A. (eds) Emergency General Surgery. Springer, Cham. https://doi.org/10.1007/978-3-319-96286-3_15

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