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Pesticide Contamination and Human Health Risk Factor

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Modern Age Environmental Problems and their Remediation

Abstract

The use of pesticide has become an integral part of modern agricultural practices. Majority of pesticides applied in agriculture are not target specific and during their application they also affect non-target organisms. Repetitive use of pesticide leads to loss of biodiversity. Continuous and non-judicious use of pesticide has leads to increase pesticide contamination in the environment. It is associated with various ecological and health problems. It leads to over three million poisoning cases annually and up to 220,000 deaths, primarily in emerging countries. Pesticides may present instantaneous danger to the user if applied inadequately or without appropriate knowledge of their toxic effects. Occupational exposure to pesticides repeatedly occurs in the case of agricultural workers in open fields and greenhouses, workers in the pesticide industry, and exterminators of house pests. Some are highly toxic and may cause serious illness and even death if spilled on the skin, inhaled, or otherwise used imprecisely. Potential future hazards to human health can be created by pesticide residues that may cause accumulation in the food chain and widespread contamination of the environment. Acute and chronic effect of pesticide contamination cause various carcinogenic, oncogenic, genotoxic and teratogenic effect on the human being. This chapter explores the different types of pesticide, their mode of action, various ways through which pesticide enters our environment (soil, air and water) lead to pesticide contamination. We also learn about the way that how pesticides enters the human body and causes various health effects and also discuss about their future perspectives.

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References

  • Agrawal A, Pandey RS, Sharma B (2010) Water pollution with special reference to pesticide contamination in India. J Water Res Protec 2:432–448

    Article  CAS  Google Scholar 

  • Aktar W, Sengupta D, Chowdhury A (2009) Impact of pesticides use in agriculture: their benefits and hazards. Interdiscip Toxicol 1:1–12

    Article  CAS  Google Scholar 

  • Alavanja MCR, Ross MK, Bonner MR et al (2013) Increased cancer burden among pesticide applicators and others due to pesticide exposure. CA Cancer J Clin 63:120–142

    Article  Google Scholar 

  • Amaral AFS (2014) Pesticides and asthma: challenges for epidemiology. Front Public Health 2:6

    Article  Google Scholar 

  • Asghar U, Malik MF, Javed A (2016) Pesticide exposure and human health: a review. J Ecosys Ecograph S5:005. doi:10.4172/2157-7625.S5-005

    Google Scholar 

  • Binienda ZK, Sarkar S, Mohammed-Saeed L et al (2013) Chronic exposure to rotenone, a dopaminergic toxin, results in peripheral neuropathy associated with dopaminergic damage. Neurosci Lett 541:233–237

    Article  CAS  Google Scholar 

  • Campo E, Swerdlow SH, Harris NL et al (2011) The 2008 WHO classification of lymphoid neoplasms and beyond: evolving concepts and practical applications. Blood 117:5019–5032

    Article  CAS  Google Scholar 

  • Claudine M, Samanic A, Roos J et al (2008) Occupational exposure to pesticides and risk of adult brain tumors. Am J Epidemiol 167:976–985

    Article  Google Scholar 

  • Cohn BA, Wolff MS, Cirillo P et al (2007) DDT and breast cancer in young women: new data on the significance of age at exposure. Environ Health Perspect 115:1406–1414

    CAS  Google Scholar 

  • Conant J, Fadem P (2008) Reproductive health problem. In a community guide to environmental health. http://en.hesperian.org/hhg/A_CommunityGuide_to_Environmental_Health:Reproductive_Health_Problems. Accessed on 24 Dec 2016

  • Couteur DG, Mclean AJ, Taylor MC et al (1999) Pesticides and Parkinson’s disease. Biomed Pharmacol 53:122–130

    Article  Google Scholar 

  • Damalas CA (2009) Understanding benefits and risks of pesticide use. Sci Res Essays 4:945–949

    Google Scholar 

  • Dich J, Zahm SH, Hanberg A et al (1997) Pesticides and cancer. Cancer Causes Control 8:420–443

    Article  CAS  Google Scholar 

  • Dreiher J, Kordysh E (2006) Non-Hodgkin lymphoma and pesticide exposure: 25 years of research. Acta Haematol 116:153–164

    Article  CAS  Google Scholar 

  • Duffard AME, Duffard R (1996) Behavioral toxicology, risk assessment, and chlorinated hydrocarbons. Environ Health Prospect 104:353–360

    Article  Google Scholar 

  • Eleftherohorinos IG (2008) Weed science: weeds, herbicides, environment, and methods for weed management. Agro Typos, Athens

    Google Scholar 

  • Emily M (2011) The encyclopedia of earth. In agricultural pesticide contamination. http://www.eoearth.org/article/Agricultural_pesticide_contamination. Accessed 20 Dec 2017

  • Fenske RA, Day EW Jr (2005) Assessment of exposure for pesticide handlers in agricultural, residential and institutional environments. In: Franklin CA, Worgan JP (eds) Occupational and Residential Exposure Assessment for Pesticides. Wiley, Chichester, pp 13–43

    Google Scholar 

  • Ferreira JD, Couto AC, Oliveira MS et al (2009) The Brazilian collaborative study group of infant acute leukemia. Environ Health Perspect 12:89–97

    Google Scholar 

  • Gilden RC, Huffling K, Sattler B (2010) Pesticides and health risks. J Obstet Gynecol Neonatal Nurs 39:103–110

    Article  Google Scholar 

  • Hardell L, Eriksson M, Lenner P et al (1981) Malignant lymphoma and exposure to chemicals, especially organic solvents, chlorophenols and phenoxy acids: a case-control study. Br J Cancer 43:169–176

    Article  CAS  Google Scholar 

  • Hayden KM, Norton MC, Darcey D et al (2010) Occupational exposure to pesticides increases the risk of incident AD: the cache county study. Neurology 74:1524–1530

    Article  CAS  Google Scholar 

  • Hoar SK, Blair A, Holmes FF et al (1986) Agricultural herbicide use and risk of lymphoma and soft-tissue sarcoma. JAMA 256:1141–1147

    Article  CAS  Google Scholar 

  • Jamal GA (1997) Neurological symptoms of organophosphorus compounds. Adv Drug React Toxicolo Rev 16:133–170

    CAS  Google Scholar 

  • Kalpana J (2016) Essay on soil pollution: defnition, causes and effects. http://www.indiaessays.com/essays/india/soilpollution/essayonsoilpollutiondefinitioncausesandeffects/1482. Accessed 3 Dec 2016

  • Kathryn RG, Peters S, Bailey HD et al (2013) Exposure to pesticides and the risk of childhood brain tumors. Cancer Causes Control 7:1269–1278

    Google Scholar 

  • Keifer MC, Firestone J (2007) Neurotoxicity of pesticides. J Agromed 1:17–25

    Article  Google Scholar 

  • Koutros S, Lynch CF, Ma X (2009) Heterocyclic aromatic amine pesticide use and human cancer risk: results from the U.S. Agricultural Health Study. Int J Cancer 124:1206–1212

    Article  CAS  Google Scholar 

  • Lah K (2011) Effects of pesticides on human health toxipedia. http://wwwtoxipediaorg/display/toxipedia/Effects+of+Pesticides+on+Human+Health. Accessed 17 Dec 2016

  • Lawrie M, David F, Jennifer C et al (1997) Our children at risk: the five worst environmental threats to their health. NRDC. https://searchworks.stanford.edu/view/3784301. Accessed on 19 Dec 2016

  • Lax SF, Kendall B, Tashiro H et al (2000) The frequency of p53, K-ras mutations, and microsatellite instability differs in uterine endometrioid and serous carcinoma. Cancer 88:814–824

    Article  CAS  Google Scholar 

  • Lifshitz M, Shahak E, Sofer S (1999) Carbamate and organophosphate poisoning in young children. Pediatr Emerg Care 15:102–103

    Article  CAS  Google Scholar 

  • Miller CS, Mitzel HC (1995) Chemical sensitivity attributed to pesticide exposure versus remodeling. Arch Environ Health 50:119–129

    Article  CAS  Google Scholar 

  • Monaco JT, Weller SC, Ashton FM (2002) Herbicide registration and environmental impact. In: Monaco TJ, Weller SC, Ashton FM (eds) Weed science: principles and practices, 4th edn. Wiley, New York, pp 84–97

    Google Scholar 

  • National Academy of Science (1975) Principles for evaluating chemicals in the environment. National Academy of Science, Washington, DC

    Google Scholar 

  • National Park Service (2016) US Department of the Interior. .Sequoia & Kings Canyon National Park: Air quality – Airborne synthetic chemicals. https://www.nps.gov/seki/learn/nature/air_synthchem.htm. Accessed 3 Dec 2016

  • Oerke EC, Dehne HW (2004) Safeguarding production-losses in major crops and the role of crop protection. Crop Prot 23:275–285

    Article  Google Scholar 

  • Ortega R, Carmona A (2012) High spatial resolution chemical imaging of inorganic and organometallic pesticides. J Environ Anal Toxicol:S4–005

    Google Scholar 

  • Owens K, Feldman J, Kepner J (2010) Wide range of diseases linked to pesticides. Pesticide-Induced Diseases Database. www.Beyondpesiticides.org/health. Accessed on 24 Dec 2016

    Google Scholar 

  • Papendick RI, Elliott LF, Dahlgren RB (1986) Environmental consequences of modern production agriculture: how can alternative agriculture address these issues and concerns? Am J Altern Agric 1:3–10

    Article  Google Scholar 

  • Perlman H (2016) U.S. Department of the Interior|U.S. Geological Survey. http://water.usgs.gov/edu/mearthgw.html. Accessed 16 Dec 2016

  • Pimentel D (2005) Environmental and economic costs of the application of pesticides primarily in the United States. Environ Dev Sustain 7:229–252

    Article  Google Scholar 

  • Porta M, Malats N, Jariod M et al (1999) Serum concentrations of organochlorine compounds and K-ras mutations in exocrine pancreatic cancer. Lancet 354:2125–2129

    Article  CAS  Google Scholar 

  • Power AG (2010) Ecosystem services and agriculture: tradeoffs and synergies. Philos Trans R Soc B 365:2959–2971

    Article  Google Scholar 

  • Qi Z, Miller GW, Voit EO (2014) Dopamine metabolism: a computational analysis of pesticide toxicity. Toxicology 6:92–101

    Article  Google Scholar 

  • Raja N, Masresha G (2015) Plant based biopesticides: safer alternative for organic food production. J Fertil Pestic 6:2

    Article  Google Scholar 

  • Savonen C (1997) Soil microorganisms object of new OSU service. Good Fruit Grower. http://www.goodfruit.com/archive/1995/6other.html. Accessed 1 Dec 2016

  • Siegel R, Naishadham D, Jemal A (2012) Cancer statistics. CA Cancer J Clin 62:10–29

    Article  Google Scholar 

  • Stella K, Charles F, Lynch X et al (2009) Aromatic amine pesticide use and human cancer risk: results from the U.S. Agricultural Health Study. Int J Cancer 124:1206–1212

    Article  Google Scholar 

  • Surgan M, Condon M, Cox C (2010) Pesticide risk indicators: unidentified inert ingredients compromise their integrity and utility. Environ Manag 45:834–841

    Article  Google Scholar 

  • Tanner RW, Langston JW (1990) Do environmental toxins cause Parkinson’s disease ? A critical review. Neurology 40:17–30

    Google Scholar 

  • Thany SH, Reynier P, Lenaers G (2013) Neurotoxicity of pesticides: its relationship with neurodegenerative diseases. Med Sci 29:273–278

    Google Scholar 

  • Trautmann NM, Porter KS, Wagenet RJ (2012) Pesticides and groundwater: a guide for the pesticide user. In: Natural resources cornell cooperative extension. http://psep.cce.cornell.edu/facts-slides-self/facts/pest-gr-gud-grw89.aspx. Accessed 16 Dec 2016

  • USEPA (2016) Assessing human health risk from pesticide. https://www.epa.gov/pesticide-science-and-assessing-pesticide-risks/assessing-human-health-risk-pesticides. Accessed 18 Dec 2016

  • Vakonaki E, Androutsopoulosa VP, Liesivuori J et al (2013) Pesticides and oncogenic modulation. Toxicology 307:42–45

    Article  CAS  Google Scholar 

  • Valenzuela MC, Arroyo GS, Pietrini VR et al (2009) Genotoxic biomonitoring of agricultural workers exposed to pesticides in the north of Sinaloa State, Mexico. Environ Int 35:1155–1159

    Article  Google Scholar 

  • Weisburger JH (2002) Comments on the history and importance of aromatic and heterocyclic amines in public health. Mutat Res 506:9–20

    Article  Google Scholar 

  • Wesseling C, Hogstedt C, Picado A et al (1997) Unintentional fatal paraquat poisonings among agricultural workers in Costa Rica: report of 15 cases. Am J Ind Med 32:433–441

    Article  CAS  Google Scholar 

  • Wolff MS, Toniolo PG, Lee EW et al (1993) Blood levels of organochlorine residues and risk of breast cancer. J Natl Cancer Inst 85:648–652

    Article  CAS  Google Scholar 

  • Zaganas I, Kapetanaki S, Mastorodemos V et al (2013) Linking pesticide exposure and dementia: what is the evidence? Toxicology 10:3–11

    Article  Google Scholar 

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Authors and Affiliations

  1. Department of Zoology, University of Delhi, Delhi, 110007, India

    Ngangbam Sarat Singh

  2. Institute of Pesticide Formulation Technology, Sector-20, Udyog Vihar, NH-8, Gurgaon, 122016, India

    Ranju Sharma, Talat Parween & P. K. Patanjali

Authors
  1. Ngangbam Sarat Singh
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  2. Ranju Sharma
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  3. Talat Parween
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  4. P. K. Patanjali
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Corresponding author

Correspondence to Ranju Sharma .

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Editors and Affiliations

  1. Center of Excellence In Environmental Studies, King Abdulaziz University, Jeddah, Saudi Arabia

    Mohammad Oves

  2. Environmental Research Laboratory, Department of Chemistry, Aligarh Muslim University, Aligarh, Uttar Pradesh, India

    Mohammad Zain Khan

  3. Department of Chemistry, King Abdulaziz University, Jeddah, Saudi Arabia

    Iqbal M.I. Ismail

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Singh, N.S., Sharma, R., Parween, T., Patanjali, P.K. (2018). Pesticide Contamination and Human Health Risk Factor. In: Oves, M., Zain Khan, M., M.I. Ismail, I. (eds) Modern Age Environmental Problems and their Remediation. Springer, Cham. https://doi.org/10.1007/978-3-319-64501-8_3

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