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Comorbidity of Migraine with Asthma and Other Atopic Disorders

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Headache and Comorbidities in Childhood and Adolescence

Part of the book series: Headache ((HEAD))

Abstract

Migraine headache and atopic disorders including asthma are both common functional syndromes of childhood in which nature of the relationship is still debated. Attacks may induce in both disorders upon exposure to potential triggers to attacks in genetically susceptible individuals. Clinical phenotype of both disorders manifests by temporary dysfunction of target tissue mediated by inflammation triggered by specific agents. Clinical features also changes after puberty due to the partial effect of female sex hormones on the process. Appropriate definition of the syndrome and differentiating from other disorders are necessary not only for correct diagnosis but also for planning of management strategies in children and adolescents. Allergic rhinosinusitis needs to be differentiated specifically from migraine even in experienced clinics. Questioning the presence of cranial autonomic symptoms is important clue in the differential diagnosis. Atopic disorder screening is particularly required in the diagnosis of migraine in childhood and adolescents. The link between both disorders of childhood seems to be far from a coincidence and some common inflammatory mechanisms are shared.

 As for conclusion, based on clinical features, laboratory findings and some practical clues in children and adolescents, accurate diagnosis of migraine and atopic disorders are very critical for physicians, pediatricians and algologists. This chapter focuses on the causal and clinical associations of migraine and atopic disorders, with supporting data from specific investigations of each of the disorders.

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Authors and Affiliations

  1. Professor of Neurology, Department of Neurology, Algology and Clinical Neurophysiology, Mersin University School of Medicine, Çiftlikköy Kampusü, Yenişehir, Mersin, 33430, Turkey

    Aynur Özge

  2. Department of Pediatrics, Hiroshima City Hiroshima Citizens Hospital 7-33, Motomachi, Naka-ku, Hiroshima, 730-8518, Japan

    Kentaro Kuwabara

Authors
  1. Aynur Özge
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  2. Kentaro Kuwabara
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Correspondence to Aynur Özge .

Editor information

Editors and Affiliations

  1. Child and Adolescent Neuropsychiatry, Sapienza University, Rome, Italy

    Vincenzo Guidetti

  2. University of São Paulo , Neuropsychiatry, Glia Institute , Ribeirão Preto, Brazil

    Marco A. Arruda

  3. Neurology, Algology and Clinical Neurophysiology, Mersin University School of Medicine, Mersin, Adana, Turkey

    Aynur Ozge

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Özge, A., Kuwabara, K. (2017). Comorbidity of Migraine with Asthma and Other Atopic Disorders. In: Guidetti, V., Arruda, M., Ozge, A. (eds) Headache and Comorbidities in Childhood and Adolescence. Headache. Springer, Cham. https://doi.org/10.1007/978-3-319-54726-8_9

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  • DOI: https://doi.org/10.1007/978-3-319-54726-8_9

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-54725-1

  • Online ISBN: 978-3-319-54726-8

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