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Diagnostic Testing in Glomerular Disease

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Glomerulonephritis

Abstract

Glomerular diseases are among the hardest diseases to diagnose. They can affect multiple organs (and thereby cause multiple symptoms) or only the kidney. While specific diseases may have a “classic” presentation, the overlap among presentations is considerable, and often the only way to diagnose a glomerular disease is by a kidney biopsy. There are many diagnostic tests that can help diagnose a glomerular disease, and more are being identified. This chapter focuses on serologic and urine tests that can be used to help diagnose a glomerular disease. The main diagnostic considerations of the two glomerular syndromes, nephritic and nephrotic, are discussed individually. In a patient with nephritic or nephrotic syndrome, clinical judgment based on the presentation will always be needed to determine if other diagnostic tests should be sent off in place of a kidney biopsy or along with a kidney biopsy.

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Authors and Affiliations

  1. Nephrology, Northwestern University Feinberg School of Medicine, Chicago, IL, USA

    James J. Paparello

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  1. James J. Paparello
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Correspondence to James J. Paparello .

Editor information

Editors and Affiliations

  1. Department of Pediatrics, NYU Langone Medical Center, New York, NY, USA

    Howard Trachtman

  2. Department of Anatomic Pathology, Cleveland Clinic, Cleveland, OH, USA

    Leal C. Herlitz

  3. Nephrology, University of Illinois at Chicago College of Medicine, Chicago, IL, USA

    Edgar V. Lerma

  4. Renal, Electrolyte and Hypertension Division, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA

    Jonathan J. Hogan

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Paparello, J.J. (2019). Diagnostic Testing in Glomerular Disease. In: Trachtman, H., Herlitz, L., Lerma, E., Hogan, J. (eds) Glomerulonephritis. Springer, Cham. https://doi.org/10.1007/978-3-319-49379-4_3

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  • DOI: https://doi.org/10.1007/978-3-319-49379-4_3

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  • Print ISBN: 978-3-319-49378-7

  • Online ISBN: 978-3-319-49379-4

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