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Endoscopic Mucosal Dissection

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Advanced Colonoscopy and Endoluminal Surgery

Abstract

Endoscopic submucosal dissection (ESD) is an innovative, advanced endoscopic approach to superficial gastrointestinal neoplasms which is becoming a “standard” treatment option and has the potential to revolutionize treatment of early alimentary cancers. Colorectal neoplasia represents an important potential niche for the clinical application of ESD in the United States given the prevalence of these tumors. ESD is a reliable but technically challenging method for en bloc resection of gastrointestinal lesions and requires dedicated equipment, a unique skill set, and experience.

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Abbreviations

CT:

Computerized tomography

EMR:

Endoscopic mucosal resection

ESD:

Endoscopic submucosal dissection

LCS:

Laparoscopic colorectal surgery

SM:

Submucosal invasion status

References

  1. Zauber AG, Winawer SJ, O'Brien MJ, et al. Colonoscopic polypectomy and long-term prevention of colorectal-cancer deaths. N Engl J Med. 2012;366(8):687–96.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  2. Zhang M, Shin EJ. Successful endoscopic strategies for difficult polypectomy. Curr Opin Gastroenterol. 2013;29(5):489–894.

    PubMed  Google Scholar 

  3. Gorgun E, Benlice C. Church J. Risk of cancer in endoscopically benign polyps unsuitable for endoscopic removal. Int J Colorectal Dis. 2014;57(5):E271–2.

    Google Scholar 

  4. Saito Y, Sakamoto T, Nakajima T, Matsuda T. Colorectal ESD: current indications and latest technical advances. Gastrointest Endosc Clin N Am. 2014;24(2):245–55.

    Article  PubMed  Google Scholar 

  5. Gotoda T, Ho K, Soetikno R, Kaltenbach T, Draganov P. Gastric ESD: current status and future directions of devices and training. Gastrointest Endosc Clin N Am. 2014;24(2):213–33.

    Article  PubMed  Google Scholar 

  6. Draganov PV, Gotoda T, Chavalitdhamrong D, Wallace MB. Techniques of endoscopic submucosal dissection: application for the western endoscopist? Gastrointest Endosc. 2013;78(5):677–88.

    Article  PubMed  Google Scholar 

  7. Sanchez-Yague A, Kaltenbach T, Raju G, Soetikno R. Advanced endoscopic resection of colorectal lesions. Gastroenterol Clin North Am. 2013;42(3):459–77.

    Article  PubMed  Google Scholar 

  8. Cohen J. A novel opportunity in minimally invasive colorectal cancer therapy: defining a role for endoscopic submucosal dissection in the United States. Diagn Ther Endosc. 2013;2013:681783.

    Article  PubMed  PubMed Central  Google Scholar 

  9. Gorgun IE. Endoscopic instruments. In: Advanced colonoscopy. New York: Springer; 2014. p. 1–16.

    Google Scholar 

  10. Toyonaga T, Man M, Morita Y, Azuma T. Endoscopic submucosal dissection (ESD) versus simplified/hybrid ESD. Gastrointest Endosc Clin N Am. 2014;24(2):191–9.

    Article  PubMed  Google Scholar 

  11. Repici A, Hassan C, Paula PD, et al. Efficacy and safety of endoscopic submucosal dissection for colorectal neoplasia: a systematic review. Endoscopy. 2012;44(2):137–50.

    Article  CAS  PubMed  Google Scholar 

  12. Tanaka S, Terasaki M, Kanao H, Oka S, Chayama K. Current status and future perspectives of endoscopic submucosal dissection for colorectal tumors. Dig Endosc. 2012;24(s1):73–9.

    Article  PubMed  Google Scholar 

  13. Lee E, Lee JB, Lee SH, Lee DH, Lee DS, Youk EG. Endoscopic submucosal dissection for colorectal tumors—1,000 colorectal ESD cases: one specialized institute’s experiences. Surg Endosc. 2013;27(1):31–9.

    Article  PubMed  Google Scholar 

  14. Oka S, Tanaka S, Saito Y, et al. Local recurrence after endoscopic resection for large colorectal neoplasia: a multicenter prospective study in Japan. Am J Gastroenterol. 2015;110:697–707.

    Article  PubMed  Google Scholar 

  15. Repici A, Pellicano R, Strangio G, Danese S, Fagoonee S, Malesci A. Endoscopic mucosal resection for early colorectal neoplasia: pathologic basis, procedures, and outcomes. Dis Colon Rectum. 2009;52(8):1502–15.

    Article  PubMed  Google Scholar 

  16. Tanaka S, Kashida H, Saito Y, et al. JGES guidelines for colorectal endoscopic submucosal dissection/endoscopic mucosal resection. Dig Endosc. 2015;27(4):417–34.

    Article  PubMed  Google Scholar 

  17. Tanaka S, Asayama N, Shigita K, Hayashi N, Oka S, Chayama K. Towards safer and appropriate application of endoscopic submucosal dissection for T1 colorectal carcinoma as total excisional biopsy: future perspectives. Dig Endosc. 2015;27(2):216–22.

    Article  PubMed  Google Scholar 

  18. Kobayashi H, Mochizuki H, Morita T, et al. Characteristics of recurrence after curative resection for T1 colorectal cancer: Japanese multicenter study. J Gastroenterol. 2011;46(2):203–11.

    Article  PubMed  Google Scholar 

  19. Kiriyama S, Saito Y, Yamamoto S, et al. Comparison of endoscopic submucosal dissection with laparoscopic-assisted colorectal surgery for early-stage colorectal cancer: a retrospective analysis. Endoscopy. 2012;44(11):1024–30.

    Article  CAS  PubMed  Google Scholar 

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Author information

Authors and Affiliations

  1. Department of Colorectal Surgery, Cleveland Clinic Foundation, 9500 Euclid Ave, Cleveland, OH, 44195, USA

    Cigdem Benlice M.D.

  2. Department of Colorectal Surgery, Digestive Disease Institute, Cleveland Clinic Foundation, 9500 Euclid Ave. A-30, Cleveland, OH, 44195, USA

    Emre Gorgun M.D., F.A.C.S., F.A.S.C.R.S.

Authors
  1. Cigdem Benlice M.D.
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  2. Emre Gorgun M.D., F.A.C.S., F.A.S.C.R.S.
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Corresponding author

Correspondence to Emre Gorgun M.D., F.A.C.S., F.A.S.C.R.S. .

Editor information

Editors and Affiliations

  1. Department of Surgery - Colon and Rectal Surgery, Keck School of Medicine of University of Southern California, Los Angeles, California, USA

    Sang W. Lee

  2. Division of Colon and Rectal Surgery Department of Surgery, Lewis Katz School of Medicine at Temple University, Philadelphia, Pennsylvania, USA

    Howard M. Ross

  3. Department of Colon and Rectal Surgery Northwell Health, Huntington Hospital Hofstra School of Medicine, Woodbury, New York, USA

    David E. Rivadeneira

  4. Case Western Reserve University School of Medicine, Cleveland, Ohio, USA

    Scott R. Steele

  5. Division of Colorectal Surgery Department of Surgery, Columbia University, New York, New York, USA

    Daniel L. Feingold

Electronic Supplementary Material

Combined endoscopic–laparoscopic surgery (CELS) (MP4 82012 kb)

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Benlice, C., Gorgun, E. (2017). Endoscopic Mucosal Dissection. In: Lee, S., Ross, H., Rivadeneira, D., Steele, S., Feingold, D. (eds) Advanced Colonoscopy and Endoluminal Surgery. Springer, Cham. https://doi.org/10.1007/978-3-319-48370-2_16

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  • DOI: https://doi.org/10.1007/978-3-319-48370-2_16

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-48368-9

  • Online ISBN: 978-3-319-48370-2

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