Abstract
Allogeneic hematopoietic stem cell transplantation (HSCT) is a potentially curative therapy for a wide variety of malignant and nonmalignant conditions, but the development of graft-versus-host disease after transplantation may cause significant morbidity and mortality. The updated National Institutes of Health Consensus Development Project on Criteria for Clinical Trials in Chronic Graft-versus-Host Disease (cGVHD) [1] clarified and built upon the 2005 NIH Consensus Conference criteria for diagnosing and scoring the severity of chronic GVHD [2]. The purpose of these guidelines is to create uniformity in clinical trials, to guide treatment, and to facilitate biomarker studies.
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References
Jagasia MH, Greinix HT, Arora M, Williams KM, Wolff D, Cowen EW, et al. National Institutes of Health Consensus Development Project on Criteria for Clinical Trials in Chronic Graft-versus-Host Disease: I. The 2014 Diagnosis and Staging Working Group Report. Biol Blood Marrow Transplant. 2015;21:389–401. e1
Filipovich AH, Weisdorf D, Pavletic S, Socie G, Wingard JR, Lee SJ, et al. National Institutes of Health consensus development project on criteria for clinical trials in chronic graft-versus-host disease: I. Diagnosis and Staging Working Group report. Biol Blood Marrow Transplant. 2005;11:945–56.
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Pinney, S.S., Alousi, A.M., Hymes, S.R. (2017). Clinical Presentation of Nonsclerotic Epidermal Chronic Graft-Versus-Host Disease and Hair and Nail Changes. In: Cotliar, J. (eds) Atlas of Graft-versus-Host Disease. Springer, Cham. https://doi.org/10.1007/978-3-319-46952-2_7
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DOI: https://doi.org/10.1007/978-3-319-46952-2_7
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