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Trigeminal neuralgia. Non-invasive techniques versus microvascular decompression. It is really available any further improvement?

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Reconstructive Neurosurgery

Part of the book series: Acta Neurochirurgica Supplementum ((NEUROCHIRURGICA,volume 101))

Abstract

Analysis of the results of the various methods for treatment of typical trigeminal neuralgia (TN) based on the literature and personal experience. The personal experience includes 847 cases: total thyzotomy in the posterior fossa 17 cases; rhyzotomy in the posterior fossa sparing the intermediate fibers 16 cases; microvascular decompression (MVD) 141 cases; controlled thermorhizotomy (PTR) 54 cases; Fogarty Balloon compression (FBC) 223 cases; glycerol ganglyolis (PGG) 12 cases; miscellaneous 48 case; medical treatment only 310 cases; cyberknife radiosurgery (CKR) 46 cases. The follow-up in this series is 1–32 years. MVD of the Vth cranial nerve in posterior fossa gives the best results in term of long-term pain relief without collateral effects in drug-resistant TN. Percutaneous techniques (PTR, PGG, FBC) are indicated in patients either without neurovascular conflict or with excessive surgical risk.

Stereotactic radiosurgery (SRS) and CKR might be considered an improvement of percutaneous and surgical techniques, but contrary to the expectations, the rate of complete pain relief at long term is lower. SRS and CKR are less effective than MVD which, in spite of the risks it entails, remains the choice treatment for typical trigeminal neuralgia.

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References

  1. Abdennebi B, Mahfouf L, Nadjahi T, etal (1997) Long-term results of percutaneous compression of the gasserian ganglion in trigeminal neuralgia (series of 200 patients). Stereotact Funct Neurosurg 68: 190–195

    Article  PubMed  CAS  Google Scholar 

  2. Adams CBT, Micro vascular compression (1989) An alternative view and hypothesis. J Neurosurg 57: 1–12

    Google Scholar 

  3. Ashkan K, Marsh H (2004) Micro vascular decompression for trigeminal neuralgia in the elderly: a review of the safety and efficacy. Neurosurgery 55: 840–850

    Article  PubMed  Google Scholar 

  4. Barker FG, Jannetta PJ, Bissonette DJ, et al (1996) The long term outcome of microvascular decompression for trigeminal neuralgia. N Engl J Med 334: 1077–1083

    Article  PubMed  Google Scholar 

  5. Brisman R (2004) Gamma knife surgery with a dose of 75 to 76.8 Gray for trigeminal neuralgia. J Neurosurg 100: 848–854

    PubMed  Google Scholar 

  6. Brisman R, Mooij R (2000) Gamma knife radiosurgery for trigeminal neuralgia: dose-volume histograms of the brainstem and trigeminal nerve. J Neurosurg 93(Suppl 3): 155–158

    PubMed  Google Scholar 

  7. Broggi G, Franzini A, Lasio G, et al (1990) Long-term results of percutaneous retrogasserian thermorhizotomy for “essential” trigeminal neuralgia: consideration on 1000 consecutive patients. Neurosurgery 26: 783–786

    Article  PubMed  CAS  Google Scholar 

  8. Broggi G, Franzini A, Giorgi C, et al (1993) Trigeminal neuralgia. New surgical strategies Acta Neurochir Suppl 58: 171–173

    CAS  Google Scholar 

  9. Broggi G, Ferroli P, Franzini A, et al (2000) Microvascular decompression for trigeminal neuralgia: comments on a series of 250 cases, including 10 patients with multiple sclerosis. J Neurol Neurosurg Psych 68: 59–64

    Article  CAS  Google Scholar 

  10. Brown JA, Pilitsis JG (2005) Percutaneous ballon compression for the treatment of trigeminal neuralgia: results in 56 patients based on balloon compression pressure monitoring. Neurosurg Focus 18(5): E10

    Article  PubMed  Google Scholar 

  11. Christensen JP (1957) Percutaneous ganglyolis of the Gasserina ganglion with normal saline as treatment of trigeminal neuralgia. Acta Neurol Lat Amer 3: 378–380

    Google Scholar 

  12. Flickinger JC, Pollok BE, Kondziolka D, et al (2001) Does increased nerve length within the treatment volume improve trigeminal neuralgia radiosurgery? A prospective double-blind, randomised study. Int J Radiat Oncol Biol Phys 51: 449–454

    PubMed  CAS  Google Scholar 

  13. Ganz JC (2002) Gamma knife radiosurgery and its possible relationship to malignancy: a review. J Neurosurg 97(Suppl 5): 644–652

    PubMed  Google Scholar 

  14. Gleadhill CA (1975) Paroxysmal trigeminal neuralgia treated by injection not producing sensory loss. Results of 200 cases. First Congress International Association for the Study of Pain. Firenze, Abstracts volume, 92 pp

    Google Scholar 

  15. Gybels JM, Sweet HW (1998) Neurosurgical treatment of persistent pain, Physiological and pathological mechanisms of human pain. Pain and headache, vol. 11. Karger, Basel

    Google Scholar 

  16. Hakanson S (1984) Trigeminal neuralgia treated by the injection of glycerol into the trigeminal cstern. Neurosrugery 9: 638–646

    Google Scholar 

  17. Hakanson S (1983) Retrogasserian glycerol injection as a treatment of tic douloureux. In: Bonica JJ, Lindblom U, Iggo A (eds) Advances in pain research and therapy. Raven Press, New York, pp 927–933

    Google Scholar 

  18. Jaeger R (1959) The result of injecting hot water into the Gasserian ganglion for the relief of tic douloureux. J Neurosurg 16: 656–663

    PubMed  CAS  Google Scholar 

  19. Jannetta PJ (1967) Arterial compression of the trigeminal nerve at the pons in patients with trigeminal neuralgia. J Neurosurg 26: 159–162

    PubMed  Google Scholar 

  20. Jefferson A (1966) Trigeminal neuralgia. Trigeminal root and ganglion injection using phenol in glycerine. In: Khighton RS, Dumke PR (eds) Pain Henry Ford Hospital Internat Symp Boston, Little Brown and Co, pp 365–371

    Google Scholar 

  21. Jelašič F (1959) Öber die Behandlung der Trigeminusneuralgie mittels mechanische Kompression des Ganglion Gasseri durchdas Foramen ovale. Acta Neurochir (Wien) 7: 440–445

    Article  Google Scholar 

  22. Kanpolat Y, Savas A, Bekar A, et al (2001) Percutaneous controlled radiofrequency trigeminal rhizotomy in the treatment of trigeminal neuralgia: 25-year experience with 1600 patients. Neurosurgery 48: 524–532

    Article  PubMed  CAS  Google Scholar 

  23. Kirschner M (1942) Die Behandlung des Trigeminusneuralgia nach Erfahrungen an 1113 Kranken. Munch Med Wschr 89: 235–239

    Google Scholar 

  24. Klun B (1992) Microvascular decompression and partial sensory rhizotomy in the treatment of trigeminal neuralgia. Personal experience with 220 patients. Neurosurgery 30: 49–52

    Article  PubMed  CAS  Google Scholar 

  25. Kondo A (2001) Microvascular decompression surgery for trigeminal neuralgia. Stereotact Funct Neurosurg 77: 187–189

    Article  PubMed  CAS  Google Scholar 

  26. Kondziolka D, Perez B, Fclickinger JC, et al (1996) Sterotactic radiosurgery for trigeminal neuralgia: a multiinstitutional study using the gamma unit. J Neurosurg 84: 940–950

    PubMed  CAS  Google Scholar 

  27. Kondziolka D, Flickinger JC, Lunsford LD, et al (1996) Trigeminal neuralgia radiosurgery: The University of Pittsburg experience. Stereotact Funct Neurosurg 66(Suppl 1): 343–348

    Article  PubMed  Google Scholar 

  28. Kondziolka D, Lacomis D, Niranjan A, et al (2000) Histological effects of trigeminal nerve radiosurgery in a primate model: implication for trigeminal neuralgia radiosurgery. Neurosurgery 46: 971–976

    Article  PubMed  CAS  Google Scholar 

  29. Lim M, Villavicencio AT, Burneikiene S, et al (2005) CyberKnife radiosurgery for idiopathic trigeminal neuralgia. Neurosurg Focus 18: 1–7

    Article  Google Scholar 

  30. Maesawa S, Salame C, Flickinger JC, et al (2001) Clinical outcomes after stereotactic radiosurgery for idiopathic trigeminal neuralgia. J Neurosurg 94: 14–20

    PubMed  CAS  Google Scholar 

  31. Maspes PE, Pagni CA (1974) A critical appraisal of pain surgery and suggestions for improving the treatment. In: Bonica JJ, Procacci P, Pagni CA (eds) Recent advances on pain. Pathophysiology and clinical aspects. Charles C. Thomas, Springfield, III, pp 201–255

    Google Scholar 

  32. Massager N, Lorenzoni J, Devrient D, et al (2004) Gamma knife surgery for idiopathic trigeminal neuralgia performed using a far-anterior cisternal target and hig dose of radiation. J Neurosurg 100: 597–605

    PubMed  Google Scholar 

  33. McLaughlin MR, Jannetta PJ, Clyde BL, etal (1999) Microvascular decompression of cranial nerves. Lessons learned after 4400 operations. J Neurosurg 90: 1–8

    PubMed  CAS  Google Scholar 

  34. Mendoza N, Illingworth RD (1995) Trigeminal neuralgia treated by microvascular decompression. A long-term follow-up study. Br J Neurosurg 9: 13–19

    Article  PubMed  CAS  Google Scholar 

  35. Meneses MS, Clemente R, Russ HH, et al (1995) Microsurgical treatment of trigeminal neuralgia. A study of 50 cases (in French). Neurochirurgie 41: 349–352

    PubMed  CAS  Google Scholar 

  36. Mullan S, Lichtor T (1983) Percutaneous microcompression of the trigeminal ganglion for trigeminal neuralgia. J Neurosurg 59: 1007–1012

    PubMed  CAS  Google Scholar 

  37. Nicol B, Régine WF, Courtney C, et al (2000) Gamma knife radiosurgery using 90 Gy for trigeminal neuralgia. J Neurosurg 93 (Suppl 3): 152–154

    PubMed  Google Scholar 

  38. Ogungbo BI, Kelly P, Kane PJ, et al (2000) Micorvascular decompression for trigeminal nevralgia. Report of outcome in patients of over 65 years of age. Br J Neurosurg 14: 23–27

    Article  PubMed  CAS  Google Scholar 

  39. Olivecrona H (1961) Trigeminal neuralgia. Triangolo 5: 60–69

    Google Scholar 

  40. Oturai AB, Jensen K, Eriksen, et al (1996) Neurosurgery for trigeminal neuralgia: comparison of alcohol block, neurectomy and radiofrequency coagulation. Clin J Pain 12: 311–315

    Article  PubMed  CAS  Google Scholar 

  41. Pagni CA (1977) Central pain and painful anesthesia. Pathophysiology and treatment of sensory deprivation syndromes due to central and peripheral nervous system lesions. In: Progr. Neurol Surg. Karger, Basel, vol. 8, pp 132–257

    Google Scholar 

  42. Pagni CA (1993) The origin of tic douloureux. An unified view. J Neurosurg Sci 37: 185–194

    PubMed  CAS  Google Scholar 

  43. Pamir MN, Zirh TA, Ozer AF, et al (1995) Microvascular decompression in the surgical management of trigeminal neuralgia. Neurosurg Rev 18: 163–167

    Article  PubMed  CAS  Google Scholar 

  44. Pollock BE (2005) Comparison of posterior fossa exploration and stereotactic radiosurgery in patients with previously nonsurgically treated idiopathic trigeminal neuralgia. Neurosurg Focus 18(5): E6

    Article  PubMed  Google Scholar 

  45. Pollock BE, Phuong LK, Foote RL, et al (2001) High-dose trigeminal neuralgia radiosurgery associated with increased risk of trigeminal nerve disfunction. Neurosurgery 49: 58–62

    Article  PubMed  CAS  Google Scholar 

  46. Pollock BE, Phuong LK, Gorman DA, et al (2002) Stereotactic radiosurgery for idiopathic trigeminal neuralgia. J Neurosurg 97: 347–353

    PubMed  Google Scholar 

  47. Régis J, Bartolomei F, Metellus P, et al (1999) Radiosurgery for trigeminal neuralgia and epilepsy. Neurosurg Clin N Am 10: 359–377

    PubMed  Google Scholar 

  48. Rogers CL, Shelter AG, Fiedler JA, et al (2000) Gamma knife radio-surgery for trigeminal neuralgia the initial experience of the Barrow Neurological Institute. Int J Radiat Oncol Biol Phys 47: 1013–1019

    PubMed  CAS  Google Scholar 

  49. Romanelli P, Heit G, Chang SD, et al (2003) Cyberknife radio-surgery for trigeminal neuralgia. Stereotact Funct Neurosurg 81: 105–109

    Article  PubMed  Google Scholar 

  50. Saini SS (1987) Retrogasserian anhydrous glycerol injection therapy in trigeminal neuralgia. Observation on 552 patients. J Neurol Neurosurg Psychiat 50: 1536–1538

    Article  PubMed  CAS  Google Scholar 

  51. Schwartz HG (1955) Gasserina ganglyolisis for trigeminal neuralgia. Souther Med J 48: 189–192

    CAS  Google Scholar 

  52. Scrivani SJ, Keith DA, Mathews ES, et al (1999) Percutaneous stereotactic differential radiofrequency thermal rhizotomy for the treatment of trigeminal neuralgia. J Oral Maxillofac Surg 57: 104–111

    Article  PubMed  CAS  Google Scholar 

  53. Sheehan J, Pan H-C, Stroila M, et al (2005) Gamma knife surgery for trigeminal neuralgia: outcomes and prognostic factors. J Neurosurg 102: 434–441

    PubMed  Google Scholar 

  54. Shelden CH (1966) Compression procedure for trigeminal neuralgia. J Neurosurg 25: 374–381

    PubMed  CAS  Google Scholar 

  55. Sindou M, Mertens P (1993) Microsurgical vascular decompression in trigeminal and glosso-vago-pharingeal neuralgia. A twenty years experience. Acta Neurochir Suppl 58: 168–17

    CAS  Google Scholar 

  56. Sindou M, Ciriano D, Fisher C (1991) Lesson from BAEP monitoring during microvascular decompression for TN and HFS. In: Schramm J, Moller AR (eds) Intraoperative neurophysiological monitoring. Springer, Berlin Heidelberg, pp 293–300

    Google Scholar 

  57. Siöqvist O (1938) Studies on pain conduction in the trigeminal nerve. A contribution to the surgical treatment of facial pain. Acta Pyschiat, Copenh Suppl 17

    Google Scholar 

  58. Skirving DJ, Dan NG (2001) A 20-year review of percutaneous balloon compression of the trigeminal ganglion. J Neurosurg 94: 913–917

    PubMed  CAS  Google Scholar 

  59. Spaziante R, Cappabianca P, Puca C, et al (1988) Subarachnoid hemorrhage and “normal pressare hydrocephalus”. Fatal complication of percutaneous microcompression of the Gasserian ganglion. Case report. Neurosurgery 22: 148–151

    Article  PubMed  CAS  Google Scholar 

  60. Sweet WH (1986) The treatment of trigeminal neuralgia (tic douloureux). N Eng J Med 315: 174–177

    CAS  Google Scholar 

  61. Sweet WH, Wepsic JG (1974) Controlled thermocoagulation of trigeminal ganglion and rootlets for differential destruction of pain fibers. I Trigeminal neuralgia. J Neurosurg 39: 143–156

    Google Scholar 

  62. Sweet WH, Poletti C (1988) Complications of percutaneous rhizotomy and microvascular decompression operations for facial pain. In: Schmidek HH, Sweet HW (eds) Current techniques in operative neurosurgery. Grüne and Stratton, Orlando, pp 1139–1143

    Google Scholar 

  63. Taarnhøj P (1954) Decompression of the trigeminal root. J Neurosurg 9: 288–290

    Google Scholar 

  64. Taha JM, Tew JM Jr (1996) Comparison of surgical treatments for trigeminal neuralgia: revaluation of radiofrequency rhizotomy. Neurosurgery 38: 865–871

    Article  PubMed  CAS  Google Scholar 

  65. Taha JM, Tew JM Jr, Buncher CR, et al (2005) A prospective 15 years follow-up of 154 consecutive patients with trigeminal neuralgia treated by percutaneous stereotactic radiofrequency thermal rhyzotomy. Neurosurg Focus 18(5): E14

    Google Scholar 

  66. Van Loveren HR, Tew JM Jr, Keller JT, et al (1982) A 10-year experience in the treatment of trigeminal neuralgia: Comparison of percutaneous stereotactic rhizotomy and posterior fossa exploration. J Neurosurg 57: 757–764

    Article  PubMed  Google Scholar 

  67. Walker AE, Miles FC, Simpson JR (1956) Partial trigeminal rhizotomy using suboccipital approach. Experience in the treatment of trigeminal neuralgia. Acta Neurol Psychiat 75: 514–521

    CAS  Google Scholar 

  68. Waltz TA, Dalessio DJ, Copeland B, et al (1989) Percutaneous injection of glycerol for the treatment of trigeminal neralgia. Clin J Pain 5: 195–198

    Article  PubMed  CAS  Google Scholar 

  69. White JC, Sweet WH (1969) Pain and the neurosurgeon. A forty-years experience. Charles C. Thomas, Springfield Ill, pp 1000

    Google Scholar 

  70. Young RF, Vermulen S, Posewitz A (1998) Gamma knife radiosurgery for idiopathic trigeminal neuralgia. Stereotact Funct Neurosurg 70(Suppl 1): 192–199

    Article  PubMed  Google Scholar 

  71. Zakrzewska JM, Lopez BJ, Kim SE, et al (2005) Patient reports of satisfaction after microvascular decompression and partial sensory rhizotomy for trigeminal neuralgia. Neurosurgery 56: 1304–1312

    Article  PubMed  Google Scholar 

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Pagni, C.A., Fariselli, L., Zeme, S. (2008). Trigeminal neuralgia. Non-invasive techniques versus microvascular decompression. It is really available any further improvement?. In: Chiu, WT., et al. Reconstructive Neurosurgery. Acta Neurochirurgica Supplementum, vol 101. Springer, Vienna. https://doi.org/10.1007/978-3-211-78205-7_5

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  • DOI: https://doi.org/10.1007/978-3-211-78205-7_5

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