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There is More to Smoking than the CNS Effects of Nicotine

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Effects of Nicotine on Biological Systems II

Part of the book series: Advances in Pharmacological Sciences ((APS))

Summary

Cigarette smoking presents a constellation of sensory and behavioral cues along with the CNS effects of nicotine. Several studies have shown that craving for cigarettes is difficult to alleviate with alternative nicotine delivery systems that do not provide these cues. Conversely, presentation of the sensory/behavioral cues of smoking using de-nicotinized cigarettes, effectively alleviates craving. The effects of de-nicotinized cigarette smoke and nicotine skin patches were compared in a sample of 20 cigarette smokers, who smoked ad lib for 2 hours while wearing nicotine or placebo skin patches that had been applied the previous night. Craving was substantially alleviated by the de-nicotinized cigarettes but only slightly affected by the nicotine patch. These results suggest that smoking cessation treatment strategies should provide replacements for the sensory/behavioral components of smoking.

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Author information

Authors and Affiliations

  1. Duke University and V.A. Medical Center, 508 Fulton St., Durham, N.C., 27705, USA

    Jed E. Rose & Frederique M. Behm

Authors
  1. Jed E. Rose
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  2. Frederique M. Behm
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Editor information

Editors and Affiliations

  1. Department of Pharmacology and Therapeutics, McGill University, 3655 Drummond Street, H3G 1Y6, Montreal, Québec, Canada

    Paul Brian Sydenham Clarke  & Maryka Quik  & 

  2. Stiftung fĂĽr Verhalten und Umwelt, Pettenkoferstrasse 12, D-80336, MĂĽnchen, Germany

    Franz Adlkofer (Sekretär) (Sekretär)

  3. Physiologisches Institut, Universität München, Pettenkoferstrasse 12, D-80336, München, Germany

    Klaus Thurau (Vorstand) (Vorstand)

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© 1995 Birkhäuser Verlag Basel

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Rose, J.E., Behm, F.M. (1995). There is More to Smoking than the CNS Effects of Nicotine. In: Clarke, P.B.S., Quik, M., Adlkofer, F., Thurau, K. (eds) Effects of Nicotine on Biological Systems II. Advances in Pharmacological Sciences. Birkhäuser Basel. https://doi.org/10.1007/978-3-0348-7445-8_31

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  • DOI: https://doi.org/10.1007/978-3-0348-7445-8_31

  • Publisher Name: Birkhäuser Basel

  • Print ISBN: 978-3-0348-7447-2

  • Online ISBN: 978-3-0348-7445-8

  • eBook Packages: Springer Book Archive

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