Skip to main content

Abstract

Ensuring sustainability is the most important task of a biobank, because biobanks are very resource-intensive infrastructures with a long-term horizon. Only a sustainable biobank can make a significant contribution to research ongoing. However, many different factors must fit and interact to enable sustainability. In this chapter, the particular challenges of biobank sustainability and their biobanking activities with a special focus on LMICs will be discussed.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 49.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 64.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book
USD 64.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

References

  1. ISO 20387:18 Biotechnology – Biobanking – General Requirements for Biobanking. (2018). Accessed March 08, 2021, from http://www.iso.org/standard/67888.html

  2. ISBER Best Practices. (2018). (4th ed.). Accessed March 08, 2021, from www.isber.org/bestpractices

  3. Shaw, D. M., Elger, B. S., & Colledge, F. (2014). What is a biobank? Differing definitions among biobank stakeholders. Clinical Genetics, 85(3), 223–227. https://doi.org/10.1111/cge.12268

    Article  CAS  PubMed  Google Scholar 

  4. Hewitt, R., & Watson, P. H. (2013). Defining biobank. Biopreservation and Biobanking, 11(5), 309–315. https://doi.org/10.1089/bio.2013.0042

    Article  PubMed  Google Scholar 

  5. Nansumba, H., Ssewanyana, I., Tai, M., & Wassenaar, D. (2020). Role of a regulatory and governance framework in human biological materials and data sharing in National Biobanks: Case studies from biobank integrating platform, Taiwan and the National Biorepository, Uganda. Wellcome Open Research, 1, 4(171). https://doi.org/10.12688/wellcomeopenres.15442.2

  6. Vodosin, P., Jorgensen, A. K., & Mendy, M. (2021). Review of regulatory frameworks governing biobanking in lower and middle income member countries of BCNet. Biopres Biobank, 19(5), 444–452.

    Article  Google Scholar 

  7. Watson, P. H., & Barnes, R. O. (2011). A proposed schema for classifying human research biobanks. Biopreservation and Biobanking, 9(4), 327–333. https://doi.org/10.1089/bio.2011.0020

    Article  PubMed  Google Scholar 

  8. Watson, P. H., Nussbeck, S. Y., Cater, C., O’Donoghue, S., Cheah, S., Matzke, L. A. M., Barnes, R. O., Bartlett, J., Carpenter, J., Grizzle, W. E., Johnston, R. N., Mes-Masson, A.-M., Murphy, L., Sexton, K., Shepherd, L., Simeon-Dubach, D., Zeps, N., & Schacter, B. (2014). A framework for biobank sustainability. Biopreservation and Biobanking, 12(1), 60–68. https://doi.org/10.1089/bio.2013.0064

    Article  PubMed  PubMed Central  Google Scholar 

  9. Simeon-Dubach, D., & Watson, P. (2014). Biobanking 3.0: Evidence based and customer focused biobanking. Clinical Biochemistry, 47(4–5), 300–308. https://doi.org/10.1016/j.clinbiochem.2013.12.018

    Article  PubMed  Google Scholar 

  10. Henderson, M. K., Kozlakidis, Z., Fachiroh, J., Wiafe, A. B., Xu, X., Ezzat, S., Wagner, H., Maques, M. M. C., & Yadav, B. K. (2020). The responses of biobanks to COVID-19. Biopreservation and Biobanking, 18(6), 483–491. https://doi.org/10.1089/bio.2020.29074.mkh

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  11. Simeon-Dubach, D., & Henderson, M. K. (2014). Sustainability in biobanking. Biopreservation and Biobanking, 12(5), 287–291. https://doi.org/10.1089/bio.2014.1251

    Article  PubMed  Google Scholar 

  12. Rao, A., Vaught, J., Tulskie, B., Olson, D., Odeh, H., McLean, J., & Moore, J. M. (2019). Critical financial challenges for biobanking: Report of a National Cancer Institute study. Biopreservation and Biobanking, 17(2), 129–138. https://doi.org/10.1089/bio.2018.0069

    Article  PubMed  PubMed Central  Google Scholar 

  13. Doucet, M., Yuille, M., Georghiou, L., & Dagher, G. (2017). Biobank sustainability: Current status and future prospects. Journal of Biorepository Science for Applied Medicine, 2017(5), 1–7. https://doi.org/10.2147/BSAM.S100899

    Article  Google Scholar 

  14. Fachiroh, J., Dwianingsih, E. K., Wahdi, A. E., Pramatasari, F. L., Hariyanto, S., Pastiwi, N., Yunus, J., Mendy, M., Scheerder, B., & Lazuardi, L. (2019). Development of a biobank from a legacy collection in Universitas Gadjah Mada, Indonesia: Proposed approach for centralized biobank development in low-resource institutions. Biopreservation and Biobanking, 17(5), 387–394. https://doi.org/10.1089/bio.2018.0125

    Article  PubMed  Google Scholar 

  15. Ferdyn, K., Glenska-Olender, J., Witon, M., Zagorska, K., Kozera, L., Chroscicka, A., & Matera-Witkiewicz, A. (2019). Quality management system in the BBMRI.Pl consortium: Status before the formation of the polish biobanking network. Biopreservation and Biobanking, 17(5), 401–409. https://doi.org/10.1089/bio.2018.0127

    Article  PubMed  Google Scholar 

  16. Jao, I., Kombe, F., Mwalukore, S., Bull, S., Parker, M., Kamuya, D., Molyneux, S., & Marsh, V. (2015). Research stakeholders’ views on benefits and challenges for public health research data sharing in Kenya: The importance of trust and social relations. PLoS One, 10(9), e0135545. https://doi.org/10.1371/journal.pone.0135545

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  17. Moodley, K., & Singh, S. (2016). “It’s all about trust”: Reflections of researchers on the complexity and controversy surrounding biobanking in South Africa. BMC Medical Ethics, 17(1), 57. https://doi.org/10.1186/s12910-016-0140-2

    Article  PubMed  PubMed Central  Google Scholar 

  18. Fernando, B., King, M., & Sumathipala, A. (2019). Advancing good governance in data sharing and biobanking – International aspects. Wellcome Open Research, 4, 184. https://doi.org/10.12688/wellcomeopenres.15540.1

  19. Mendy, M., Caboux, E., Sylla, B., Dillner, J., Chinquee, J., & Wild, C. (2014). BCNet survey participants. Infrastructure and facilities for human biobanking in low- and middle-income countries: A situation analysis. Pathobiology, 81, 252–260. https://doi.org/10.1159/000362093

    Article  PubMed  Google Scholar 

  20. Zawati, M. N., Tasse, A. M., Mendy, M., Caboux, E., Lang, M., & on Behalf of Biobank and Cohort Building Network Members. (2018). Barriers and opportunities in consent and access procedures in low-and middle-income country biobanks: Meeting notes from the BCNet training and general assembly. Biopreservation and Biobanking, 16(3), 171–178. https://doi.org/10.1089/bio.2017.0081

  21. Bull, S., & Bhagwandins N. (2020). The ethics of data sharing and biobanking in health research. Wellcome Open Research, 5, 270. https://doi.org/10.12688/wellcomeopenres.16351.

  22. Franzen, S. R., Chandler, C., & Lang, T. (2017). Health research capacity development in low and middle income countries: Reality or rhetoric? A systematic meta-narrative review of the qualitative literature. BMJ Open, 7(1), e012332. https://doi.org/10.1136/bmjopen-2016-012332

    Article  PubMed  PubMed Central  Google Scholar 

  23. Ghaffar, A., Ijsselmuiden, C., & Zicker, F. (2008). Changing mindsets. Research capacity strengthening in low- and middleincome countries. Council on Health Research for Development (COHRED).

    Google Scholar 

  24. Blanchet, K., Nam, S.L., Ramalingam, B., Pozo-Martin, F. (2017). Governance and capacity to manage resilience of health systems: Towards a new conceptual framework. International Journal of Health Policy Management, 6(8), 431–435. https://doi.org/10.15171/ijhpm.2017.36

  25. Stewart, R., El-Harakeh, A., & Cherian, S. A. (2020). Evidence synthesis communities in low-income and middle-income countries and the COVID-19 response. Lancet, 396(10262), 1539–1541. https://doi.org/10.1016/S0140-6736(20)32141-3

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  26. Merdad, L., Aldakhil, L., Gadi, R., Assidi, M., Saddick, S. Y., Abuzenadah, A., Vaught, J., Buhmeida, A., & Al-Qahtani, M. H. (2017). Assessment of knowledge about biobanking among healthcare students and their willingness to donate biospecimens. BMC Medical Ethics, 18(32). https://doi.org/10.1186/s12910-017-0195-8

  27. He, N., Guo, Y., He, M., Qiang, W., & Li, H. (2017). Attitudes and perceptions of cancer patients toward biospecimen donation for cancer research: A cross-sectional survey among Chinese cancer patients. Biopreservation and Biobanking, 15(4), 366–374. https://doi.org/10.1089/bio.2016.0079

    Article  PubMed  Google Scholar 

  28. Tindana, P., & de Vries, J. (2016). Broad consent for genomic research and biobanking: Perspectives from low- and middle-income countries. Annual Review of Genomics and Human Genetics, 17, 375–393. https://doi.org/10.1146/annurev-genom-083115-022456

    Article  CAS  PubMed  Google Scholar 

  29. Tindana, P., Yakubu, A., Staunton, C., Matimba, A., Littler, K., Madden, E., Munung, N. S., de Vries, J., & Members of the H3Africa Consortium. (2019). Engaging research ethics committees to develop an ethics and governance framework for best practices in genomic research and biobanking in Africa: The H3Africa model. BMC Medical Ethics, 20(1), 69. https://doi.org/10.1186/s12910-019-0398-2

    Article  PubMed  PubMed Central  Google Scholar 

  30. Gao, H., Jiang, J., Feng, B., Guo, A., Hong, H., & Liu, S. (2018). Parental attitudes and willingness to donate children’s biospecimens for congenital heart disease research: A cross-sectional study in Shanghai, China. BMJ Open, 8(10), e022290. https://doi.org/10.1136/bmjopen-2018-022290

    Article  PubMed  PubMed Central  Google Scholar 

  31. Goodyear-Smith, F., Bazemore, A., Coffman, M., Fortier, R. D. W., Howe, A., Kidd, M., Phillips, R., Rouleau, K., & van Weel, C. (2019). Research gaps in the organisation of primary healthcare in low-income and middle-income countries and ways to address them: A mixed-methods approach. BMJ Global Health, 4(Suppl 8), e001482. https://doi.org/10.1136/bmjgh-2019-001482

    Article  PubMed  PubMed Central  Google Scholar 

  32. Goodyear-Smith, F., Bazemore, A., Coffman, M., Fortier, R., Howe, A., Kidd, M., Phillips, R., Rouleau, K., & van Weel, C. (2019). Primary care financing: A systematic assessment of research priorities in low- and middle-income countries. BMJ Global Health, 4(Suppl 8), e001483. https://doi.org/10.1136/bmjgh-2019-001483

    Article  PubMed  PubMed Central  Google Scholar 

  33. Akinyemi, R. O., Akinwande, K., Diala, S., Adeleye, O., Ajose, A., Issa, K., Owusu, D., Boamah, I., Yahaya, I. S., Jomoh, A. O., Imoh, L., Fakunle, G., Akpalu, A., Sarfo, F., Wahab, K., Sanya, E., Owolabi, L., Obiako, R., Osaigbovo, G., et al. (2018). Biobanking in a challenging African environment: Unique experience from the SIREN project. Biopreservation and Biobanking, 16(3), 217–232. https://doi.org/10.1089/bio.2017.0113

    Article  PubMed  PubMed Central  Google Scholar 

  34. Abdelhafiz, A. S., Sultan, E. A., Ziady, H. H., Ahmed, E. O., Khairy, W. A., Sayed, D. M., Zaki, R., Fouda, M. A., & Labib, R. M. (2019). What Egyptians think. Knowledge, attitude, and opinions of Egyptian patients towards biobanking issues. BMC Medical Ethics, 20(57). https://doi.org/10.1186/s12910-019-0394-6

  35. Mezinska, S., Kaleja, J., Mileiko, I., Santare, D., Rovite, V., & Tzivian, L. (2020). Public awareness of and attitudes towards research biobanks in Latvia. BMC Medical Ethics, 21(1), 65. https://doi.org/10.1186/s12910-020-00506-1

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  36. Lhousni, S., Daoudi, F., Belmokhtar, I., Belmokhtar, K. Y., Abda, N., Boulouiz, R., Tajir, M., Bellaoui, M., & Quarzane, M. (2020). Patients’ knowledge and attitude toward biobanks in Eastern Morocco. Biopreservation and Biobanking, 18(3), 189–195.

    Article  Google Scholar 

  37. De Oliveira, L., Dias, M. A. B., Jeyabalan, A., Payne, B., Redman, C. W., Magee, L., Poston, L., Chappell, L., Seed, P., von Dadelszen, P., & Roberts, J. M. (2018). Creating biobanks in low and middle-income countries to improve knowledge – The PREPARE initiative. Pregnancy Hypertens, 13, 62–44. https://doi.org/10.1016/j.preghy.2018.05.007

    Article  PubMed  PubMed Central  Google Scholar 

  38. Sumathipala, A., Siribaddana, S., Hotopf, M., McGuffin, P., Glozier, N., Ball, H., et al. (2013). The Sri Lankan twin registry: 2012 update. Twin Research and Human Genetics, 16(1), 307–312. https://doi.org/10.1017/thg.2012.119

    Article  PubMed  Google Scholar 

  39. Henderson, M. K., & Kozlakidis, Z. (2018). ISBER and the biobanking and cohort network (BCNet): A strengthened partnership. Biopreservation and Biobanking, 16(5), 393–394. https://doi.org/10.1089/bio.2018.29043.mkh

    Article  PubMed  PubMed Central  Google Scholar 

  40. Vaught, J. (2016). Biobanking and biosecurity initiatives in Africa. Biopreservation and Biobanking, 14(5), 355–356. https://doi.org/10.1089/bio.2016.29009.jjv

    Article  PubMed  Google Scholar 

Download references

Disclaimer

Where authors are identified as personnel of the International Agency for Research on Cancer/WHO, the authors alone are responsible for the views expressed in this article, and they do not necessarily represent the decisions, policy or views of the International Agency for Research on Cancer/WHO.

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Daniel Simeon-Dubach .

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2022 The Author(s), under exclusive license to Springer Nature Switzerland AG

About this chapter

Check for updates. Verify currency and authenticity via CrossMark

Cite this chapter

Simeon-Dubach, D., Kozlakidis, Z. (2022). Sustainability of Biobanks and Biobanking in LMICs. In: Sargsyan, K., Huppertz, B., Gramatiuk, S. (eds) Biobanks in Low- and Middle-Income Countries: Relevance, Setup and Management. Springer, Cham. https://doi.org/10.1007/978-3-030-87637-1_26

Download citation

Publish with us

Policies and ethics