Abstract
Crossing between two or more parents is a fundamental way to generate superior genetic variants through genetic recombination and transgressive segregation in modern crop breeding. The selection of parents and crosses is the first key step for the success of crop breeding. The traditional method for screening parents and crosses is primarily based on phenotypic performance and genetic differences between parents and the breeders’ empirical expertise. With the availability of genome-wide molecular markers and other genomic information, computer simulation offers a computational approach to simulate genetic recombination events between parents and progeny segregation of crosses and to generate segregation populations of any virtual crosses for various breeding schemes. Genomic selection (GS) enables to estimate breeding values (BVs) of the segregation individuals of crosses. Therefore, the integration of computer simulation and GS leads to an advanced genomic tool, named genomic cross prediction, to predict the genetic performance of different types of crosses by evaluating BVs and genetic variances of their segregation populations, enhancing the potential of success in crossbreeding. This chapter overviews the strategies and methods of genomic cross prediction and illustrates its application potential in crops, especially flax linseed breeding.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
References
Bernardo R (2015) Genomewide selection of parental inbreds: classes of loci and virtual biparental populations. Crop Sci 55:2586–2595
Chakravarti A (1991) A graphical representation of genetic and physical maps: the Marey map. Genomics 11:219–222
Cloutier S, Ragupathy R, Miranda E, Radovanovic N, Reimer E et al (2012) Integrated consensus genetic and physical maps of flax (Linum usitatissimum L.). Theor Appl Genet 125:1783–1795
Covarrubias-Pazaran G (2016) Genome-assisted prediction of quantitative traits using the R package sommer. PLoS One 11:e0156744
Crossa J, Pérez P, de los Campos G, Mahuku G, Dreisigacker S, et al. (2011) Genomic selection and prediction in plant breeding. J Crop Imrov 25:239–261
Crossa J, Perez P, Hickey J, Burgueno J, Ornella L et al (2013) Genomic prediction in CIMMYT maize and wheat breeding programs. Heredity (Edinb) 112:48–60
Daetwyler, H.D.; Pong-Wong, R.; Villanueva, B.; Woolliams, J.A. (2010) The impact of genetic architecture on genome-wide evaluation methods. Genetics 185:1021–1031
Desta ZA, Ortiz R (2014) Genomic selection: genome-wide prediction in plant improvement. Trends Plant Sci 19:592–601
Diederichsen A, Kusters PM, Kessler D, Bainas Z, Gugel RK (2013) Assembling a core collection from the flax world collection maintained by plant gene resources of Canada. Genet Resour Crop Evol 60:1479–1485
Endelman JB (2011) Ridge regression and other kernels for genomic selection with R package rrBLUP. Plant Genome 4:250–255
Faux AM, Gorjanc G, Gaynor RC, Battagin M, Edwards SM et al (2016) AlphaSim: software for breeding program simulation. Plant Genome 9. https://doi.org/10.3835/plantgenome2016.3802.0013
Fedoroff NV (2010) The past, present and future of crop genetic modification. Nat Biotechnol 27:461–465
He L, Xiao J, Rashid KY, Jia G, Li P et al (2019a) Evaluation of genomic prediction for pasmo resistance in flax. Int J Mol Sci 20:359
He L, Xiao J, Rashid KY, Yao Z, Li P et al (2019b) Genome-wide association studies for pasmo resistance in flax (Linum usitatissimum L.). Front. Plant Sci 9:1982
Henderson CR (1975) Best linear unbiased estimation and prediction under a selection model. Biometrics 31:423–447
Hoyos-Villegas V, Arief VN, Yang W-H, Sun M, DeLacy IH et al (2019) QuLinePlus: extending plant breeding strategy and genetic model simulation to cross-pollinated populations—case studies in forage breeding. Heredity 122:684–695
Iwata H, Jannink JL (2011) Accuracy of genomic selection prediction in barley breeding programs: a simulation study based on the real single nucleotide polymorphism data ofbBarley breeding lines. Crop Sci 51:1915–1927
Jahufer MZZ, Luo D (2018) DeltaGen: a comprehensive decision support tool for plant breeders. Crop Sci. https://doi.org/10.2135/cropsci2017.2107.0456
Jannink, J.L. (2010) Dynamics of long-term genomic selection. Genet Sel Evol 42:35
Khan N, Shazadee H, Jia B, Bartaula S, Sertse D et al (2021) Genomic prediction for drought stress and root development traits in flax (Linum usitatissimum L.). Front Plant Sci
Lan S, Zheng C, Hauck K, McCausland M, Duguid SD et al (2020) Genomic prediction accuracy of seven breeding selection traits improved by QTL identification in flax. Int J Mol Sci 21:1577
Lande R, Thompson R (1990) Efficiency of marker-assisted selection in the improvement of quantitative traits. Genetics 124:743–756
Li H, Zhang L, Hu J, Zhang F, Chen B et al (2017) Genome-wide association mapping reveals the genetic control underlying branch angle in rapeseed (Brassica napus L.). front. Plant Sci 8:1054
Lin Z, Cogan NO, Pembleton LW, Spangenberg GC, Forster JW et al (2016) Genetic gain and inbreeding from genomic selection in a simulated commercial breeding program for perennial ryegrass. Plant Genome 9. https://doi.org/10.3835/plantgenome2015.3806.0046
Lipka AE, Kandianis CB, Hudson ME, Yu J, Drnevich J et al (2015) From association to prediction: statistical methods for the dissection and selection of complex traits in plants. Curr Opin Plant Biol 24:110–118
Liu X, Huang M, Fan B, Buckler ES, Zhang Z (2016) Iterative usage of fixed and random effect models for powerful and efficient genome-wide association studies. PLoS Genet 12:e1005767
Liu H, Tessema BB, Jensen J, Cericola F, Andersen JR et al (2019) ADAM-plant: a software for stochastic simulations of plant breeding from molecular to phenotypic level and from simple selection to complex speed breeding programs. Front Plant Sci 9:1926
Meuwissen THE, Hayes BJ, Goddard ME (2001) Prediction of total genetic value using genome-wide dense marker maps. Genetics 157:1819–1829
Mohammadi M, Tiede T, Smith KP (2015) PopVar: a genome-wide procedure for predicting genetic variance and correlated response in biparental breeding populations. Crop Sci 55:2068–2077
Perez P, de los Campos G (2014) Genome-wide regression and prediction with the BGLR statistical package. Genetics 198:483–495
Price AL, Patterson NJ, Plenge RM, Weinblatt ME, Shadick NA et al (2006) Principal components analysis corrects for stratification in genome-wide association studies. Nat Genet 38:904–909
Ren WL, Wen YJ, Dunwell JM, Zhang YM (2017) pKWmEB: integration of Kruskal-Wallis test with empirical Bayes under polygenic background control for multi-locus genome-wide association study. Heredity (Edinb) 120:208–218
Riedelsheimer C, Czedik-Eysenberg A, Grieder C, Lisec J, Technow F et al (2012) Genomic and metabolic prediction of complex heterotic traits in hybrid maize. Nat Genet 44:217–220
Schaefer CM, Bernardo R (2013) Genomewide association mapping of flowering time, kernel composition, and disease resistance in historical Minnesota maize inbreds. Crop Sci 53:2518–2529
Schmid KJ, Thorwarth P (2014) Genomic selection in barley breeding. In: Kumlehn J, Stein N (eds) Biotechnological approaches to barley improvement biotechnology in agriculture and forestry. Springer, Berlin/Heidelberg, pp 367–378
Schnell FW, Utz HF (1975) F1-leistung und elternwahl euphy-derzu ¨chtungvonselbstbefruchtern,. in Bericht u ¨ber die Arbeitstagung der Vereinigung O “sterreichischer Pflanzenzu” chter BAL Gumpenstein, Gumpenstein, Austria:243–248
Sekine D, Yabe S (2020) Simulation-based optimization of genomic selection scheme for accelerating genetic gain while preventing inbreeding depression in onion breeding. Breed Sci 70:594–604
Siberchicot A, Bessy A, Gueguen L, Marais GAB (2017) MareyMap online: a user-friendly web application and database service for estimating recombination rates using physical and genetic maps. Genome Biol Evol 9:2506–2509
Soto-Cerda BJ, Diederichsen A, Ragupathy R, Cloutier S (2013) Genetic characterization of a core collection of flax (Linum usitatissimum L.) suitable for association mapping studies and evidence of divergent selection between fiber and linseed types. BMC Plant Biol 13:78
Spindel, J.; Begum, H.; Akdemir, D.; Virk, P.; Collard, B.; Redona, E.; Atlin, G.; Jannink, J.L.; McCouch, S.R. (2015) Genomic selection and association mapping in rice (Oryza sativa): effect of trait genetic architecture, training population composition, marker number and statistical model on accuracy of rice genomic selection in elite, tropical rice breeding lines. PLoS Genet. 2015, 11, (2), e1004982.
Sun J, Khan M, Amir R, Gul A (2020) Genomic selection in wheat breeding. In: Ozturk M, Gul A (eds) Climate change and food security with emphasis on wheat. Academic Press, pp 321–330
Tamba CL, Ni YL, Zhang YM (2017) Iterative sure independence screening EM-Bayesian LASSO algorithm for multi-locus genome-wide association studies. PLoS Comput Biol 13:e1005357
Thavamanikumar S, Dolferus R, Thumma BR (2015) Comparison of genomic selection models to predict flowering time and spike grain number in two hexaploid wheat doubled haploid populations. G3 (Bethesda) 5:1991–1998
Tiede T, Kumar L, Mohammadi M, Smith KP (2015a) Predicting genetic variance in bi-parental breeding populations is more accurate when explicitly modeling the segregation of informative genomewide markers. Mol Breed 35:199
Tiede T, Mohammadi M, Smith KP (2015b) PopVar: genomic breeding tools: genetic variance prediction and cross-validation. R package version 121
Voorrips RE, Maliepaard CA (2012) The simulation of meiosis in diploid and tetraploid organisms using various genetic models. BMC Bioinform 13:248
Wang J, Dieters D (2008) QuLine, A software that simulates breeding programs for developing inbred lines Version 2.1. User’s Manual
Wang J, van Ginkel M, Podlich D, Ye G, Trethowan R et al (2003) Comparison of two breeding strategies by computer simulation. Crop Sci 43:1764–1773
Wang J, Singh RP, Braun HJ, Pfeiffer WH (2009) Investigating the efficiency of the single backcrossing breeding strategy through computer simulation. Theor Appl Genet 118:683–694
Wang Z, Hobson N, Galindo L, Zhu S, Shi D et al (2012) The genome of flax (Linum usitatissimum) assembled de novo from short shotgun sequence reads. Plant J 72:461–473
Wang SB, Feng JY, Ren WL, Huang B, Zhou L et al (2016) Improving power and accuracy of genome-wide association studies via a multi-locus mixed linear model methodology. Sci Rep 6:19444
Wang X, Xu Y, Hu ZL, Xu CW (2018) Genomic selection methods for crop improvement: current status and prospects. Crop J 6:330–340
Wen YJ, Zhang H, Ni YL, Huang B, Zhang J et al (2018) Methodological implementation of mixed linear models in multi-locus genome-wide association studies. Brief Bioinform 19:700–712
Xu Y, Lu Y, Xie C, Gao S, Wan J et al (2012) Whole-genome strategies for marker-assisted plant breeding. Mol Breed 29:833–854
Yao J, Zhao D, Chen X, Zhang Y, Wang J (2018) Use of genomic selection and breeding simulation in cross prediction for improvement of yield and quality in wheat (Triticum aestivum L.). Crop J 6:353–365
You FM, Booker HM, Duguid SD, Jia G, Cloutier S (2016a) Accuracy of genomic selection in biparental populations of flax (Linum usitatissimum L.). Crop J 4:290–303
You FM, Duguid SD, Lam I, Cloutier S, Rashid KY et al (2016b) Pedigrees and genetic base of flax cultivars registered in Canada. Can J Plant Sci 96:837–852
You FM, Jia G, Xiao J, Duguid SD, Rashid KY et al (2017) Genetic variability of 27 traits in a core collection of flax (Linum usitatissimum L.). front. Plant Sci 8:1636
You FM, Xiao J, Li P, Yao Z, Gao J et al (2018) Chromosome-scale pseudomolecules refined by optical, physical, and genetic maps in flax. Plant J 95:371–384
Yu J, Pressoir G, Briggs WH, Vroh Bi I, Yamasaki M et al (2006) A unified mixed-model method for association mapping that accounts for multiple levels of relatedness. Nat Genet 38:203–208
Zhang YM, Tamba CL (2018) A fast mrMLM algorithm for multi-locus genome-wide association studies. bioRxiv. https://doi.org/10.1101/341784
Zhang J, Feng JY, Ni YL, Wen YJ, Niu Y et al (2017) pLARmEB: integration of least angle regression with empirical Bayes for multilocus genome-wide association studies. Heredity (Edinb) 118:517–524
Zhang Y-W, Tamba CL, Wen Y-J, Li P, Ren W-L et al (2020) mrMLM v4.0: an R platform for multi-locus genome-wide association studies. BioRxiv. https://doi.org/10.1101/2020.1103.1104.976464
Zhong, S.; Jannink, J.-L. (2007) Using quantitative trait loci results to discriminate among crosses on the basis of their progeny mean and variance. Genetics 177, 567–576
Zingaretti ML, Monfort A, Perez-Enciso M (2019) pSBVB: a versatile simulation tool to evaluate genomic selection in polyploid species. G3 (Bethesda) 9:327–334
Acknowledgments
This work is a part of the 4DWheat project, and was also supported by the total Utilization Flax GENomics (TUFGEN) project. The two projects were funded by Agriculture and Agri-Food Canada, Genome Canada and co-funders from the wheat and flax industries in Canada including producer groups. The authors also recognize the support provided by Genome Prairie.
Author information
Authors and Affiliations
Corresponding author
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2022 The Author(s), under exclusive license to Springer Nature Switzerland AG
About this chapter
Cite this chapter
You, F.M., Zheng, C., Bartaula, S., Khan, N., Wang, J., Cloutier, S. (2022). Genomic Cross Prediction for Linseed Improvement. In: Gosal, S.S., Wani, S.H. (eds) Accelerated Plant Breeding, Volume 4. Springer, Cham. https://doi.org/10.1007/978-3-030-81107-5_13
Download citation
DOI: https://doi.org/10.1007/978-3-030-81107-5_13
Published:
Publisher Name: Springer, Cham
Print ISBN: 978-3-030-81106-8
Online ISBN: 978-3-030-81107-5
eBook Packages: Biomedical and Life SciencesBiomedical and Life Sciences (R0)