Abstract
HIV has always been, and continues to be, as much a social phenomenon and challenge as it is a clinical one. Controlling transmission and containing the virus relies on engaging with and adjusting the social contours of behaviours and practices. Efforts to prevent acquisition and enable ‘protection’ against HIV continue to illuminate the complexity, multiplicity and dynamism of relationships in context, from the micro level of person to person interaction extending up to the global stage of political economies. Despite major biomedical breakthroughs over the course of the HIV epidemic, the influence of the social has not diminished. What risks being diluted through the optimism evoked by the biomedical promise though is how immediately visible and relevant the role of the social remains in efforts to prevent, control and perhaps ‘eliminate’ HIV.
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References
Brown, G., Reeders, D., Dowsett, G. W., Ellard, J., Carman, M., Hendry, N., et al. (2015). Investigating combination HIV prevention: Isolated interventions or complex system. Journal of the International AIDS Society, 18(1), 20499.
Busza, J., Phillips, A. N., Mushati, P., Chiyaka, T., Magutshwa, S., Musemburi, S., et al. (2020). Understanding early uptake of PrEP by female sex workers in Zimbabwe. AIDS Care. https://doi.org/10.1080/09540121.2020.1832192.
Cáceres, C. F., Koechlin, F., Goicochea, P., Sow, P. S., O’Reilly, K. R., Mayer, K. H., et al. (2015). The promises and challenges of pre-exposure prophylaxis as part of the emerging paradigm of combination HIV prevention. Journal of the International AIDS Society, 18, 19949.
Cohen, M. S., Chen, Y. Q., McCauley, M., Gamble, T., Hosseinipour, M. C., Kumarasamy, N., et al. (2011). Prevention of HIV-1 infection with early antiretroviral therapy. New England Journal of Medicine, 365(6), 493–505.
Cowan, F. M., Delany-Moretlwe, S., Sanders, E. J., Mugo, N. R., Guedou, F. A., Alary, M., et al. (2016). PrEP implementation research in Africa: What is new? Journal of the International AIDS Society, 19, 21101.
Eakle, R., Bourne, A., Mbogua, J., Mutanha, N., & Rees, H. (2018). Exploring acceptability of oral PrEP prior to implementation among female sex workers in South Africa. Journal of the International AIDS Society, 21(2), e25081.
Eisinger, R. W., Dieffenbach, C. W., & Fauci, A. S. (2019). HIV viral load and transmissibility of HIV infection: Undetectable equals Untransmittable. JAMA, 321(5), 451–452.
Galea, J. T., Baruch, R., & Brown, B. (2018). ¡ PrEP Ya! Latin America wants PrEP, and Brazil leads the way. The Lancet HIV, 5(3), e110–e1e2.
Hankins, C. A., & de Zalduondo, B. O. (2010). Combination prevention: A deeper understanding of effective HIV prevention. AIDS, 24, S70–S80.
Hodges-Mameletzis, I., Fonner, V. A., Dalal, S., Mugo, N., Msimanga-Radebe, B., & Baggaley, R. (2019). Pre-exposure prophylaxis for HIV prevention in women: Current status and future directions. Drugs, 79(12), 1263–1276.
Kenworthy, N., Thomann, M., & Parker, R. (2018). From a global crisis to the ‘end of AIDS’: New epidemics of signification. Global Public Health, 13(8), 960–971.
Kinuthia, J., Pintye, J., Abuna, F., Mugwanya, K. K., Lagat, H., Onyango, D., et al. (2020). Pre-exposure prophylaxis uptake and early continuation among pregnant and post-partum women within maternal and child health clinics in Kenya: Results from an implementation programme. The Lancet HIV, 7(1), e38–e48.
Kippax, S. (2003). Sexual health interventions are unsuitable for experimental evaluation. In J. M. Stephenson, J. Imrie, & C. Bonell (Eds.), Effective sexual health interventions (pp. 17–48). Oxford: Oxford University Press.
Kurth, A. E., Celum, C., Baeten, J. M., Vermund, S. H., & Wasserheit, J. N. (2011). Combination HIV prevention: Significance, challenges, and opportunities. Current HIV/AIDS Reports, 8(1), 62–72.
Laborde, N. D., Spinello, M., & Whitacre, R. (2019, June 17). “Zero infections. Zero deaths. Zero stigma.” Somatosphere. Retrieved November 26, 2020, from http://somatosphere.net/2019/zero-infections-zero-deaths-zero-stigma.html/.
Luz, P. M., Veloso, V. G., & Grinsztejn, B. (2019). The HIV epidemic in Latin America: Accomplishments and challenges on treatment and prevention. Current Opinion in HIV and AIDS, 14(5), 366.
Mahase, E. (2020). HIV prevention injection is more effective than daily pill, trials show. British Medical Journal, 371, m4433.
Mameletzis, I., Dalal, S., Msimanga-Radebe, B., & Rodolph, M. (2018). Going global: The adoption of the World Health Organization’s enabling recommendation on oral pre-exposure prophylaxis for HIV. Sexual Health, 15(6), 489.
Mayer, C. M., Owaraganise, A., Kabami, J., Kwarisiima, D., Koss, C. A., Charlebois, E. D., et al. (2019). Distance to clinic is a barrier to Pr EP uptake and visit attendance in a community in rural Uganda. Journal of the International AIDS Society, 22(4), e25276.
Montenegro, L., Velasque, L., LeGrand, S., Whetten, K., Rafael, R. D. M. R., & Malta, M. (2020). Public health, HIV care and prevention, human rights and democracy at a crossroad in Brazil. AIDS and Behavior, 224(1), 1–4.
O’Reilly, K. R., Fonner, V. A., Kennedy, C. E., Yeh, P. T., & Sweat, M. D. (2020). The paradox of HIV prevention: Did biomedical prevention trials show how effective behavioral prevention can be? AIDS, 34(14), 2007–2011.
Patton, C., & Kim, H. J. (2012). The cost of science: Knowledge and ethics in the HIV pre-exposure trials. Journal of Bioethical Inquiry, 9, 295–310.
Perez-Brumer, A. (2019). HIV biomedical prevention science and the business of gender and sexual diversity. Doctoral thesis. Columbia University, New York.
Pillay, D., Stankevitz, K., Lanham, M., Ridgeway, K., Murire, M., Briedenhann, E., et al. (2020). Factors influencing uptake, continuation, and discontinuation of oral PrEP among clients at sex worker and MSM facilities in South Africa. PLoS One, 15(4), e0228620.
Poteat, T., Malik, M., van der Merwe, L. L. A., Cloete, A., Adams, D., Nonyane, B. A., et al. (2020). PrEP awareness and engagement among transgender women in South Africa: A cross-sectional, mixed methods study. The Lancet HIV, 7(12), e825–e834. https://doi.org/10.1016/S2352-3018(20)30119-3.
Rodger, A. J., Cambiano, V., Bruun, T., Vernazza, P., Collins, S., Degen, O., et al. (2019). Risk of HIV transmission through condomless sex in serodifferent gay couples with the HIV-positive PARTNER taking suppressive antiretroviral therapy (PARTNER): Final results of a multicentre, prospective, observational study. Lancet, 393(10189), 2428–2438.
Rosengarten, M., & Murphy, M. (2019). ‘A wager on the future’: A practical response to HIV pre-exposure prophylaxis (PrEP) and the stubborn fact of process. Social Theory and Health, 18(1), 1–15.
Syversten, J. L. (2019, August 12). The social life of PrEP in Kenya. Somatosphere. Retrieved November 26, 2020, from http://somatosphere.net/2019/the-social-life-of-prep-in-kenya.html/
Tolley, E. E., Zangeneh, S. Z., Chau, G., Eron, J., Grinsztejn, B., Humphries, H., et al. (2020). Acceptability of long-acting injectable Cabotegravir (CAB LA) in HIV-uninfected individuals: HPTN 077. AIDS and Behavior, 24(9), 2520–2531.
Torres-Cruz, C., & Suárez-Díaz, E. (2020). The stratified biomedicalization of HIV prevention in Mexico City. Global Public Health, 14(4), 598–610.
UNAIDS. (2009). Combination prevention: Strategic HIV prevention programmes founded on good practice. In A background paper for the UNAIDS prevention reference group meeting, 3–5 December 2009. Geneva: UNAIDS.
Wahome, E. W., Graham, S. M., Thiong’o, A. N., Mohamed, K., Oduor, T., Gichuru, E., et al. (2020). PrEP uptake and adherence in relation to HIV-1 incidence among Kenyan men who have sex with men. EClinicalMedicine, 26, 100541.
Well, B., & Ledin, C. (2019, November 4). PrEP at the after/party: The ‘post-AIDS’ politics of Frank Ocean’s “PrEP+”. Somatosphere. Retrieved November 26, 2020, from http://somatosphere.net/2019/prep-at-the-after-party.html/.
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Bernays, S., Bourne, A., Kippax, S., Aggleton, P., Parker, R. (2021). Remaking HIV Prevention: The Promise of TasP, U=U and PrEP. In: Bernays, S., Bourne, A., Kippax, S., Aggleton, P., Parker, R. (eds) Remaking HIV Prevention in the 21st Century. Social Aspects of HIV, vol 5. Springer, Cham. https://doi.org/10.1007/978-3-030-69819-5_1
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