Abstract
Universal lesion detection from computed tomography (CT) slices is important for comprehensive disease screening. Since each lesion can locate in multiple adjacent slices, 3D context modeling is of great significance for developing automated lesion detection algorithms. In this work, we propose a Modified Pseudo-3D Feature Pyramid Network (MP3D FPN) that leverages depthwise separable convolutional filters and a group transform module (GTM) to efficiently extract 3D context enhanced 2D features for universal lesion detection in CT slices. To facilitate faster convergence, a novel 3D network pre-training method is derived using solely large-scale 2D object detection dataset in the natural image domain. We demonstrate that with the novel pre-training method, the proposed MP3D FPN achieves state-of-the-art detection performance on the DeepLesion dataset (3.48% absolute improvement in the sensitivity of FPs@0.5), significantly surpassing the baseline method by up to 6.06% (in MAP@0.5) which adopts 2D convolution for 3D context modeling. Moreover, the proposed 3D pre-trained weights can potentially be used to boost the performance of other 3D medical image analysis tasks.
This work was done when Jincheng Xu was an intern at Deepwise AI Lab.
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Acknowledgements
This work is funded by National Key Research and Development Program of China (No. 2019YFC0118101), MOST-2018AAA0102004 and NSFC-61625201. We would like to thank Yemin Shi for valuable discussions.
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Zhang, S. et al. (2020). Revisiting 3D Context Modeling with Supervised Pre-training for Universal Lesion Detection in CT Slices. In: Martel, A.L., et al. Medical Image Computing and Computer Assisted Intervention – MICCAI 2020. MICCAI 2020. Lecture Notes in Computer Science(), vol 12264. Springer, Cham. https://doi.org/10.1007/978-3-030-59719-1_53
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