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BiVACOR Total Artificial Heart

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Mechanical Support for Heart Failure

Abstract

The BiVACOR TAH is a cardiovascular device designed to replace the entire function of a failing human heart. It is a latest generation device that uses maglev and rotary blood pump technology to suspend a single wear-free spinning disc, in wide, blood-friendly gaps to provide a long-term solution for heart failure patients. The pump is electrically powered with a small, external, portable controller via a single percutaneous driveline. Over the last years, the BiVACOR program achieved significant development milestones toward a first-article device; several features were incorporated to provide a small, durable, physiological, and biocompatible heart replacement.

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Abbreviations

AoP:

Aortic pressure

BTT:

Bridge to transplant

CPB:

Cardiopulmonary bypass

DT:

Destination therapy

EFS:

Early feasibility study

HMW, LMW:

High, Low molecular weight

HQ:

Head-flow (e.g., HQ-curve)

HTx:

Heart transplantation

LAP:

Left atrial pressure

PAP:

Pulmonary artery pressure

pfHb:

Plasma-free hemoglobin

RAP:

Right atrial pressure

RBP:

Rotary blood pump

SVC, IVC:

Superior, inferior vena cava

TAH:

Total artificial heart

VAD:

Ventricular assist device

vWF:

Von Willebrand Factor

VZP:

Virtual zero power (e.g., VZP controller)

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Author information

Authors and Affiliations

  1. BiVACOR, Inc., Houston, TX, USA

    Daniel L. Timms PhD & Frank Nestler PhD

Authors
  1. Daniel L. Timms PhD
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  2. Frank Nestler PhD
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Corresponding author

Correspondence to Daniel L. Timms PhD .

Editor information

Editors and Affiliations

  1. Lerner Research Institute, Cleveland Clinic, Cleveland Clinic Lerner College of Medicine of Case Western Reserve University Cleveland Clinic, Cleveland, OH, USA

    Jamshid H. Karimov

  2. Lerner Research Institute, Cleveland Clinic, Cleveland Clinic Lerner College of Medicine of Case Western Reserve University Cleveland Clinic, Cleveland, OH, USA

    Kiyotaka Fukamachi

  3. Kaufman Center for Heart Failure Heart, Thoracic, and Vascular Institute, Cleveland Clinic Lerner College of Medicine of Case Western Reserve University Cleveland Clinic, Cleveland, OH, USA

    Randall C. Starling

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Timms, D.L., Nestler, F. (2020). BiVACOR Total Artificial Heart. In: Karimov, J., Fukamachi, K., Starling, R. (eds) Mechanical Support for Heart Failure . Springer, Cham. https://doi.org/10.1007/978-3-030-47809-4_35

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  • DOI: https://doi.org/10.1007/978-3-030-47809-4_35

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-030-47808-7

  • Online ISBN: 978-3-030-47809-4

  • eBook Packages: MedicineMedicine (R0)

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