Abstract
Fusion failure of nasal process and oropalatal shelves leads to alveolar cleft which necessitates secondary alveolar bone grafting. There are various donor sites to develop autografts that each has their own advantages and disadvantages. Autogenous bone from intraoral or extraoral donor sites is the gold standard for treatment of large craniomaxillofacial defects. Tissue engineering merges the fields of cell biology, biomaterial engineering, and medicine to fabricate new functional tissues. Changing cell sources, smart scaffolds, dynamic cell culture methods, and bedside modification are the main approaches that scientists are trying to use to enhance success rate in bone regeneration.
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Khojasteh, A., Nadjmi, N. (2021). Future Trends in Alveolar Cleft Osteoplasty. In: Keyhan, S.O., Fattahi, T., Bagheri, S.C., Bohluli, B., Amirzade-Iranaq, M.H. (eds) Integrated Procedures in Facial Cosmetic Surgery. Springer, Cham. https://doi.org/10.1007/978-3-030-46993-1_44
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