Skip to main content

Signed Laplacian Deep Learning with Adversarial Augmentation for Improved Mammography Diagnosis

  • Conference paper
  • First Online:
Medical Image Computing and Computer Assisted Intervention – MICCAI 2019 (MICCAI 2019)

Part of the book series: Lecture Notes in Computer Science ((LNIP,volume 11769))

Abstract

Computer-aided breast cancer diagnosis in mammography is limited by inadequate data and the similarity between benign and cancerous masses. To address this, we propose a signed graph regularized deep neural network with adversarial augmentation, named DiagNet. Firstly, we use adversarial learning to generate positive and negative mass-contained mammograms for each mass class. After that, a signed similarity graph is built upon the expanded data to further highlight the discrimination. Finally, a deep convolutional neural network is trained by jointly optimizing the signed graph regularization and classification loss. Experiments show that the DiagNet framework outperforms the state-of-the-art in breast mass diagnosis in mammography.

H. Li and D. Chen—These authors contribute equally to this work.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 84.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 109.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Similar content being viewed by others

References

  1. Antoniou, A., Storkey, A., Edwards, H.: Data augmentation generative adversarial networks. arXiv preprint arXiv:1711.04340 (2017)

  2. Chen, D., Lv, J., Davies, M.E.: Learning discriminative representation with signed Laplacian restricted Boltzmann machine. arXiv preprint arXiv:1808.09389 (2018)

  3. Chen, D., Lv, J., Yi, Z.: Unsupervised multi-manifold clustering by learning deep representation. In: Workshops at the 31th AAAI Conference on Artificial Intelligence (AAAI), pp. 385–391 (2017)

    Google Scholar 

  4. Chen, D., Lv, J., Yi, Z.: Graph regularized restricted Boltzmann machine. IEEE Trans. Neural Netw. Learn. Syst. 29(6), 2651–2659 (2018)

    Article  MathSciNet  Google Scholar 

  5. Chollet, F.: Xception: deep learning with depthwise separable convolutions. In: Proceedings of the IEEE Conference on Computer Vision and Pattern Recognition, pp. 1251–1258 (2017)

    Google Scholar 

  6. DeSantis, C., Ma, J., Bryan, L., Jemal, A.: Breast cancer statistics, 2013. CA: Cancer J. Clin. 64(1), 52–62 (2014)

    Google Scholar 

  7. Dhungel, N., Carneiro, G., Bradley, A.P.: The automated learning of deep features for breast mass classification from mammograms. In: Ourselin, S., Joskowicz, L., Sabuncu, M.R., Unal, G., Wells, W. (eds.) MICCAI 2016. LNCS, vol. 9901, pp. 106–114. Springer, Cham (2016). https://doi.org/10.1007/978-3-319-46723-8_13

    Chapter  Google Scholar 

  8. Domingues, I., Sales, E., Cardoso, J., Pereira, W.: INbreast-database masses characterization. In: XXIII CBEB (2012)

    Google Scholar 

  9. Goodfellow, I., et al.: Generative adversarial nets. In: Advances in Neural Information Processing Systems, pp. 2672–2680 (2014)

    Google Scholar 

  10. Kurakin, A., Goodfellow, I.J., Bengio, S.: Adversarial machine learning at scale (2017)

    Google Scholar 

  11. Li, H., Chen, D., Nailon, W.H., Davies, M.E., Laurenson, D.: A deep dual-path network for improved mammogram image processing. In: International Conference on Acoustics, Speech and Signal Processing (2019)

    Google Scholar 

  12. Li, H., Chen, D., Nailon, W.H., Davies, M.E., Laurenson, D.: Improved breast mass segmentation in mammograms with conditional residual U-Net. In: Stoyanov, D., et al. (eds.) RAMBO/BIA/TIA-2018. LNCS, vol. 11040, pp. 81–89. Springer, Cham (2018). https://doi.org/10.1007/978-3-030-00946-5_9

    Chapter  Google Scholar 

  13. Moreira, I.C., Amaral, I., Domingues, I., Cardoso, A., Cardoso, M.J., Cardoso, J.S.: INbreast: toward a full-field digital mammographic database. Acad. Radiol. 19(2), 236–248 (2012)

    Article  Google Scholar 

  14. Nair, V., Hinton, G.E.: Rectified linear units improve restricted Boltzmann machines. In: Proceedings of the 27th International Conference on Machine Learning, ICML 2010, pp. 807–814 (2010)

    Google Scholar 

  15. Seung, H.S., Lee, D.D.: The manifold ways of perception. Science 290(5500), 2268–2269 (2000)

    Article  Google Scholar 

  16. Shams, S., Platania, R., Zhang, J., Kim, J., Lee, K., Park, S.-J.: Deep generative breast cancer screening and diagnosis. In: Frangi, A.F., Schnabel, J.A., Davatzikos, C., Alberola-López, C., Fichtinger, G. (eds.) MICCAI 2018. LNCS, vol. 11071, pp. 859–867. Springer, Cham (2018). https://doi.org/10.1007/978-3-030-00934-2_95

    Chapter  Google Scholar 

  17. Wu, E., Wu, K., Cox, D., Lotter, W.: Conditional infilling GANs for data augmentation in mammogram classification. In: Stoyanov, D., et al. (eds.) RAMBO/BIA/TIA -2018. LNCS, vol. 11040, pp. 98–106. Springer, Cham (2018). https://doi.org/10.1007/978-3-030-00946-5_11

    Chapter  Google Scholar 

  18. Yu, Y., Qian, H., Hu, Y.Q.: Derivative-free optimization via classification. In: Thirtieth AAAI Conference on Artificial Intelligence (2016)

    Google Scholar 

  19. Yu, Y., Qu, W.Y., Li, N., Guo, Z.: Open-category classification by adversarial sample generation. In: International Joint Conference on Artificial Intelligence (2017)

    Google Scholar 

  20. Zhu, W., Lou, Q., Vang, Y.S., Xie, X.: Deep multi-instance networks with sparse label assignment for whole mammogram classification. In: Descoteaux, M., Maier-Hein, L., Franz, A., Jannin, P., Collins, D.L., Duchesne, S. (eds.) MICCAI 2017. LNCS, vol. 10435, pp. 603–611. Springer, Cham (2017). https://doi.org/10.1007/978-3-319-66179-7_69

    Chapter  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Heyi Li .

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2019 Springer Nature Switzerland AG

About this paper

Check for updates. Verify currency and authenticity via CrossMark

Cite this paper

Li, H., Chen, D., Nailon, W.H., Davies, M.E., Laurenson, D.I. (2019). Signed Laplacian Deep Learning with Adversarial Augmentation for Improved Mammography Diagnosis. In: Shen, D., et al. Medical Image Computing and Computer Assisted Intervention – MICCAI 2019. MICCAI 2019. Lecture Notes in Computer Science(), vol 11769. Springer, Cham. https://doi.org/10.1007/978-3-030-32226-7_54

Download citation

  • DOI: https://doi.org/10.1007/978-3-030-32226-7_54

  • Published:

  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-030-32225-0

  • Online ISBN: 978-3-030-32226-7

  • eBook Packages: Computer ScienceComputer Science (R0)

Publish with us

Policies and ethics