Abstract
Automatic delineation and measurement of main organs such as liver is one of the critical steps for assessment of hepatic diseases, planning and postoperative or treatment follow-up. However, addressing this problem typically requires performing computed tomography (CT) scanning and complicated post-processing of the resulting scans using slice-by-slice techniques. In this paper, we show that 3D organ shape can be automatically predicted directly from topogram images, which are easier to acquire and have limited exposure to radiation during acquisition, compared to CT scans. We evaluate our approach on the challenging task of predicting liver shape using a generative model. We also demonstrate that our method can be combined with user annotations, such as a 2D mask, for improved prediction accuracy. We show compelling results on 3D liver shape reconstruction and volume estimation on 2129 CT scans (This feature is based on research, and is not commercially available. Due to regulatory reasons its future availability cannot be guaranteed).
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
References
Albarqouni, S., Fotouhi, J., Navab, N.: X-ray in-depth decomposition: revealing the latent structures. In: Descoteaux, M., Maier-Hein, L., Franz, A., Jannin, P., Collins, D.L., Duchesne, S. (eds.) MICCAI 2017. LNCS, vol. 10435, pp. 444–452. Springer, Cham (2017). https://doi.org/10.1007/978-3-319-66179-7_51
Balashova, E., Singh, V., Wang, J., Teixeira, B., Chen, T., Funkhouser, T.: Structure-aware shape synthesis. In: 3DV, pp. 140–149. IEEE (2018)
Bogo, F., Kanazawa, A., Lassner, C., Gehler, P., Romero, J., Black, M.J.: Keep it SMPL: automatic estimation of 3D human pose and shape from a single image. In: Leibe, B., Matas, J., Sebe, N., Welling, M. (eds.) ECCV 2016. LNCS, vol. 9909, pp. 561–578. Springer, Cham (2016). https://doi.org/10.1007/978-3-319-46454-1_34
Christ, P.F., et al.: Automatic liver and tumor segmentation of CT and MRI volumes using cascaded fully convolutional neural networks. arXiv preprint arXiv:1702.05970 (2017)
Dou, Q., Chen, H., Jin, Y., Yu, L., Qin, J., Heng, P.-A.: 3D deeply supervised network for automatic liver segmentation from CT volumes. In: Ourselin, S., Joskowicz, L., Sabuncu, M.R., Unal, G., Wells, W. (eds.) MICCAI 2016. LNCS, vol. 9901, pp. 149–157. Springer, Cham (2016). https://doi.org/10.1007/978-3-319-46723-8_18
Foruzan, A.H., Chen, Y.W.: Improved segmentation of low-contrast lesions using sigmoid edge model. Int. J. Comput. Assist. Radiol. Surg. 11(7), 1267–1283 (2016)
Gadelha, M., Maji, S., Wang, R.: 3D shape induction from 2D views of multiple objects. In: 3DV, pp. 402–411. IEEE (2017)
Girdhar, R., Fouhey, D.F., Rodriguez, M., Gupta, A.: Learning a predictable and generative vector representation for objects. In: Leibe, B., Matas, J., Sebe, N., Welling, M. (eds.) ECCV 2016. LNCS, vol. 9910, pp. 484–499. Springer, Cham (2016). https://doi.org/10.1007/978-3-319-46466-4_29
Häme, Y., Pollari, M.: Semi-automatic liver tumor segmentation with hidden Markov measure field model and non-parametric distribution estimation. Med. image Anal. 16(1), 140–149 (2012)
Heimann, T., et al.: Comparison and evaluation of methods for liver segmentation from CT datasets. IEEE Trans. Med. Imaging 28(8), 1251–1265 (2009)
Ioffe, S., Szegedy, C.: Batch normalization: accelerating deep network training by reducing internal covariate shift. arXiv preprint arXiv:1502.03167 (2015)
Kar, A., Tulsiani, S., Carreira, J., Malik, J.: Category-specific object reconstruction from a single image. In: CVPR, pp. 1966–1974 (2015)
Kingma, D.P., Ba, J.: Adam: a method for stochastic optimization. arXiv preprint arXiv:1412.6980 (2014)
Kingma, D.P., Welling, M.: Auto-encoding variational Bayes (2014)
Li, G., Chen, X., Shi, F., Zhu, W., Tian, J., Xiang, D.: Automatic liver segmentation based on shape constraints and deformable graph cut in CT images. IEEE Trans. Image Process. 24(12), 5315–5329 (2015)
Lorensen, W.E., Cline, H.E.: Marching cubes: a high resolution 3D surface construction algorithm. In: ACM Siggraph Computer Graphics, vol. 21, pp. 163–169. ACM (1987)
Lu, F., Wu, F., Hu, P., Peng, Z., Kong, D.: Automatic 3D liver location and segmentation via convolutional neural network and graph cut. Int. J. Comput. Assist. Radiol. Surg. 12(2), 171–182 (2017)
Mayo-Smith, W.W., Hara, A.K., Mahesh, M., Sahani, D.V., Pavlicek, W.: How I do it: managing radiation dose in CT. Radiology 273(3), 657–672 (2014)
Mharib, A.M., Ramli, A.R., Mashohor, S., Mahmood, R.B.: Survey on liver CT image segmentation methods. Artif. Intell. Rev. 37(2), 83 (2012)
Nair, V., Hinton, G.E.: Rectified linear units improve restricted boltzmann machines. In: ICML, pp. 807–814 (2010)
Qi, C.R., Su, H., Nießner, M., Dai, A., Yan, M., Guibas, L.J.: Volumetric and multi-view CNNs for object classification on 3D data. In: CVPR, pp. 5648–5656 (2016)
Qin, B., et al.: Accurate vessel extraction via tensor completion of background layer in X-ray coronary angiograms. Pattern Recogn. 87, 38–54 (2019)
Ronneberger, O., Fischer, P., Brox, T.: U-net: convolutional networks for biomedical image segmentation. In: Navab, N., Hornegger, J., Wells, W.M., Frangi, A.F. (eds.) MICCAI 2015. LNCS, vol. 9351, pp. 234–241. Springer, Cham (2015). https://doi.org/10.1007/978-3-319-24574-4_28
Schertler, T., et al.: Dual-source computed tomography in patients with acute chest pain: feasibility and image quality. Eur. Radiol. 17(12), 3179–3188 (2007)
Sharma, A., Grau, O., Fritz, M.: VConv-DAE: deep volumetric shape learning without object labels. In: Hua, G., Jégou, H. (eds.) ECCV 2016. LNCS, vol. 9915, pp. 236–250. Springer, Cham (2016). https://doi.org/10.1007/978-3-319-49409-8_20
Sioutos, N., de Coronado, S., Haber, M.W., Hartel, F.W., Shaiu, W.L., Wright, L.W.: NCI thesaurus: a semantic model integrating cancer-related clinical and molecular information. J. Biomed. Inf. 40(1), 30–43 (2007)
Vicente, S., Carreira, J., Agapito, L., Batista, J.: Reconstructing PASCAL VOC. In: CVPR, pp. 41–48 (2014)
Wu, J., et al.: Single image 3D interpreter network. In: Leibe, B., Matas, J., Sebe, N., Welling, M. (eds.) ECCV 2016. LNCS, vol. 9910, pp. 365–382. Springer, Cham (2016). https://doi.org/10.1007/978-3-319-46466-4_22
Wu, J., Zhang, C., Xue, T., Freeman, B., Tenenbaum, J.: Learning a probabilistic latent space of object shapes via 3D generative-adversarial modeling. In: Advances in Neural Information Processing Systems, pp. 82–90 (2016)
Yang, D., et al.: Automatic liver segmentation using an adversarial image-to-image network. In: Descoteaux, M., Maier-Hein, L., Franz, A., Jannin, P., Collins, D.L., Duchesne, S. (eds.) MICCAI 2017. LNCS, vol. 10435, pp. 507–515. Springer, Cham (2017). https://doi.org/10.1007/978-3-319-66179-7_58
Zhang, Y., Miao, S., Mansi, T., Liao, R.: Task driven generative modeling for unsupervised domain adaptation: application to X-ray image segmentation. In: Frangi, A.F., Schnabel, J.A., Davatzikos, C., Alberola-López, C., Fichtinger, G. (eds.) MICCAI 2018. LNCS, vol. 11071, pp. 599–607. Springer, Cham (2018). https://doi.org/10.1007/978-3-030-00934-2_67
Zhu, Y., Prummer, S., Wang, P., Chen, T., Comaniciu, D., Ostermeier, M.: Dynamic layer separation for coronary DSA and enhancement in fluoroscopic sequences. In: Yang, G.-Z., Hawkes, D., Rueckert, D., Noble, A., Taylor, C. (eds.) MICCAI 2009. LNCS, vol. 5762, pp. 877–884. Springer, Heidelberg (2009). https://doi.org/10.1007/978-3-642-04271-3_106
Acknowledgements
We thank Daguang Xu for help with anatomical part labelling and discussions; Thomas Funkhouser, Terrence Chen, Kai Ma, and members of the Princeton Graphics and Vision Group for helpful suggestions; Sungheon Gene Kim, Linda Moy, Krzysztof Geras, and Kyunghyun Cho for discussions on medical applications of the proposed method. This work was supported by Siemens Healthcare and NSF-GRFP.
Author information
Authors and Affiliations
Corresponding author
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2019 Springer Nature Switzerland AG
About this paper
Cite this paper
Balashova, E., Wang, J., Singh, V., Georgescu, B., Teixeira, B., Kapoor, A. (2019). 3D Organ Shape Reconstruction from Topogram Images. In: Chung, A., Gee, J., Yushkevich, P., Bao, S. (eds) Information Processing in Medical Imaging. IPMI 2019. Lecture Notes in Computer Science(), vol 11492. Springer, Cham. https://doi.org/10.1007/978-3-030-20351-1_26
Download citation
DOI: https://doi.org/10.1007/978-3-030-20351-1_26
Published:
Publisher Name: Springer, Cham
Print ISBN: 978-3-030-20350-4
Online ISBN: 978-3-030-20351-1
eBook Packages: Computer ScienceComputer Science (R0)