Abstract
Populations of bone marrow stromal cells (BMSCs, also known as bone marrow-derived “mesenchymal stem cells”) contain a subset of cells that are able to recapitulate the formation of a bone/marrow organ (skeletal stem cells, SSCs). The biological properties of BMSC cultures are assessed by a variety of assays, both in vitro and in vivo. Application of these assays in an appropriate fashion provides a great deal of information on the role of BMSCs, and the subset of SSCs, in health and in disease.
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Robey, P.G., Kuznetsov, S.A., Riminucci, M., Bianco, P. (2014). Bone Marrow Stromal Cell Assays: In Vitro and In Vivo. In: Hilton, M. (eds) Skeletal Development and Repair. Methods in Molecular Biology, vol 1130. Humana Press, Totowa, NJ. https://doi.org/10.1007/978-1-62703-989-5_21
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DOI: https://doi.org/10.1007/978-1-62703-989-5_21
Publisher Name: Humana Press, Totowa, NJ
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Online ISBN: 978-1-62703-989-5
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