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Bone Marrow Stromal Cell Assays: In Vitro and In Vivo

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Skeletal Development and Repair

Part of the book series: Methods in Molecular Biology ((MIMB,volume 1130))

Abstract

Populations of bone marrow stromal cells (BMSCs, also known as bone marrow-derived “mesenchymal stem cells”) contain a subset of cells that are able to recapitulate the formation of a bone/marrow organ (skeletal stem cells, SSCs). The biological properties of BMSC cultures are assessed by a variety of assays, both in vitro and in vivo. Application of these assays in an appropriate fashion provides a great deal of information on the role of BMSCs, and the subset of SSCs, in health and in disease.

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Robey, P.G., Kuznetsov, S.A., Riminucci, M., Bianco, P. (2014). Bone Marrow Stromal Cell Assays: In Vitro and In Vivo. In: Hilton, M. (eds) Skeletal Development and Repair. Methods in Molecular Biology, vol 1130. Humana Press, Totowa, NJ. https://doi.org/10.1007/978-1-62703-989-5_21

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  • DOI: https://doi.org/10.1007/978-1-62703-989-5_21

  • Publisher Name: Humana Press, Totowa, NJ

  • Print ISBN: 978-1-62703-988-8

  • Online ISBN: 978-1-62703-989-5

  • eBook Packages: Springer Protocols

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