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The Role of MicroRNAs in Human Diseases

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miRNomics: MicroRNA Biology and Computational Analysis

Part of the book series: Methods in Molecular Biology ((MIMB,volume 1107))

Abstract

About 20 years have passed since the discovery of the first microRNA (miRNA) and by now microRNAs are implicated in a variety of physiological and pathological processes. Since the discovery of the powerful effect miRNAs have on biological processes, it has been suggested that mutations affecting miRNA function may play a role in the pathogenesis of human diseases. Over the past several years microRNAs have been found to play a major role in various human diseases. In addition, many studies aim to apply miRNAs for diagnostic and therapeutic applications in human diseases. In this chapter, we summarize the role of miRNAs in pathological processes and discuss how miRNAs could be used as disease biomarkers.

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Authors and Affiliations

  1. Department of Neuroscience, Institute of Health Science, University of Dokuz Eylul, Izmir, Turkey

    Kemal Uğur Tüfekci, Meryem Gülfem Öner & Şermin Genç

  2. Department of Internal Medicine, School of Medicine, University of Dokuz Eylul, Izmir, Turkey

    Ralph Leo Johan Meuwissen

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  1. Kemal Uğur Tüfekci
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  2. Meryem Gülfem Öner
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  3. Ralph Leo Johan Meuwissen
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  4. Şermin Genç
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Editors and Affiliations

  1. Dabburiya Village, Israel

    Malik Yousef

  2. Izmir Institute of Technology, Izmir, Turkey

    Jens Allmer

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Tüfekci, K.U., Öner, M.G., Meuwissen, R.L.J., Genç, Ş. (2014). The Role of MicroRNAs in Human Diseases. In: Yousef, M., Allmer, J. (eds) miRNomics: MicroRNA Biology and Computational Analysis. Methods in Molecular Biology, vol 1107. Humana Press, Totowa, NJ. https://doi.org/10.1007/978-1-62703-748-8_3

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  • DOI: https://doi.org/10.1007/978-1-62703-748-8_3

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