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High-Throughput Screening Using Dengue Virus Reporter Genomes

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Antiviral Methods and Protocols

Part of the book series: Methods in Molecular Biology ((MIMB,volume 1030))

Abstract

Large-scale antiviral drug discovery and systematic identification of host factors promoting or restricting virus replication require robust, scalable, and cost-effective assay systems that allow for high throughput and automation. Here we describe the construction and application of full-length infectious dengue virus reporter genomes for such screening applications.

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Fischl, W., Bartenschlager, R. (2013). High-Throughput Screening Using Dengue Virus Reporter Genomes. In: Gong, E. (eds) Antiviral Methods and Protocols. Methods in Molecular Biology, vol 1030. Humana Press, Totowa, NJ. https://doi.org/10.1007/978-1-62703-484-5_17

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  • DOI: https://doi.org/10.1007/978-1-62703-484-5_17

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  • Publisher Name: Humana Press, Totowa, NJ

  • Print ISBN: 978-1-62703-483-8

  • Online ISBN: 978-1-62703-484-5

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