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Impact of HLA Matching and HLA Antibodies in Organ Transplantation: A Collaborative Transplant Study View

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Immunogenetics

Part of the book series: Methods in Molecular Biology ((MIMB,volume 882))

Abstract

The Collaborative Transplant Study (CTS) was initiated in 1982 in Heidelberg, Germany, and originated from the need to gain further insight into the complex problems and risks involved in human organ transplantation. Currently, more than 400 transplant centers in 45 countries are contributing to this voluntary international effort, and from the beginning of the study, the impact on graft outcome of immunological factors, such as matching for HLA antigens and allosensitization to HLA and non-HLA antigens, have been areas of interest. Herein, we summarize the recent findings from the CTS on these two topics.

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Acknowledgments

We gratefully acknowledge the generous support of the staff members at participating CTS centers.

Author information

Authors and Affiliations

  1. Department of Transplantation Immunology, Institute of Immunology, University of Heidelberg, Heidelberg, Germany

    Caner Süsal & Gerhard Opelz

Authors
  1. Caner Süsal
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  2. Gerhard Opelz
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Corresponding author

Correspondence to Caner Süsal .

Editor information

Editors and Affiliations

  1. PathWest Laboratory Medicine, Department of Clinical Immunology, Royal Perth Hospital, Wellington Street, Perth, 6000, Australia

    Frank T. Christiansen

  2. Australian Red Cross Blood Service, National Transplant Services, The Royal Melbourne Hospital, 150-154 Batman Street, Melbourne VIC, 3000, Australia

    Brian D. Tait

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Süsal, C., Opelz, G. (2012). Impact of HLA Matching and HLA Antibodies in Organ Transplantation: A Collaborative Transplant Study View. In: Christiansen, F., Tait, B. (eds) Immunogenetics. Methods in Molecular Biology, vol 882. Humana Press, Totowa, NJ. https://doi.org/10.1007/978-1-61779-842-9_15

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  • DOI: https://doi.org/10.1007/978-1-61779-842-9_15

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  • Publisher Name: Humana Press, Totowa, NJ

  • Print ISBN: 978-1-61779-841-2

  • Online ISBN: 978-1-61779-842-9

  • eBook Packages: Springer Protocols

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