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Detection and Phylogenetic Assessment of Conserved Synteny Derived from Whole Genome Duplications

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Evolutionary Genomics

Part of the book series: Methods in Molecular Biology ((MIMB,volume 855))

Abstract

Identification of intragenomic conservation of gene compositions in multiple chromosomal segments led to evidence of whole genome (WGDs) duplications. The process by which WGDs have been maintained and decayed provides us with clues for understanding how the genome evolves. In this chapter, we summarize current understanding of phylogenetic distribution and evolutionary impact of WGDs, introduce basic procedures to detect conserved synteny, and discuss typical pitfalls, as well as biological insights.

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Author information

Authors and Affiliations

  1. Genome Resource and Analysis Unit, RIKEN Center for Developmental Biology, Chuo-ku, Kobe, Japan

    Shigehiro Kuraku

  2. Department of Biology, University of Konstanz, Constance, Germany

    Axel Meyer

Authors
  1. Shigehiro Kuraku
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  2. Axel Meyer
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Corresponding author

Correspondence to Shigehiro Kuraku .

Editor information

Editors and Affiliations

  1. Department of Computer Science, ETH Zürich, Universitätsstr. 6, Zürich, 8092, Switzerland

    Maria Anisimova

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Kuraku, S., Meyer, A. (2012). Detection and Phylogenetic Assessment of Conserved Synteny Derived from Whole Genome Duplications. In: Anisimova, M. (eds) Evolutionary Genomics. Methods in Molecular Biology, vol 855. Humana Press, Totowa, NJ. https://doi.org/10.1007/978-1-61779-582-4_14

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  • DOI: https://doi.org/10.1007/978-1-61779-582-4_14

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  • Publisher Name: Humana Press, Totowa, NJ

  • Print ISBN: 978-1-61779-581-7

  • Online ISBN: 978-1-61779-582-4

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