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Standardization in Synthetic Biology

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Synthetic Gene Networks

Part of the book series: Methods in Molecular Biology ((MIMB,volume 813))

Abstract

Synthetic Biology is founded on the idea that complex biological systems are built most effectively when the task is divided in abstracted layers and all required components are readily available and well-described. This requires interdisciplinary collaboration at several levels and a common understanding of the functioning of each component. Standardization of the physical composition and the description of each part is required as well as a controlled vocabulary to aid design and ensure interoperability. Here, we describe standardization initiatives from several disciplines, which can contribute to Synthetic Biology. We provide examples of the concerted standardization efforts of the BioBricks Foundation comprising the request for comments (RFC) and the Registry of Standardized Biological parts as well as the international Genetically Engineered Machine (iGEM) competition.

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Authors and Affiliations

  1. Institute for Biochemistry and Biology, University of Potsdam, Potsdam, Germany

    Kristian M. Müller & Katja M. Arndt

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  1. Kristian M. Müller
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  2. Katja M. Arndt
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Correspondence to Kristian M. Müller .

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Editors and Affiliations

  1. Inst. Biologie II, Zentrum für Biologische Signalstudien, Universität Freiburg, Stübeweg 51, Freiburg, 79108, Germany

    Wilfried Weber

  2. Dept. Ingenieurwissenschaften, Biosysteme (BSSE), ETH Zürich, Mattenstr. 26, Basel, 4058, Switzerland

    Martin Fussenegger

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Müller, K.M., Arndt, K.M. (2012). Standardization in Synthetic Biology. In: Weber, W., Fussenegger, M. (eds) Synthetic Gene Networks. Methods in Molecular Biology, vol 813. Humana Press. https://doi.org/10.1007/978-1-61779-412-4_2

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  • DOI: https://doi.org/10.1007/978-1-61779-412-4_2

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  • Publisher Name: Humana Press

  • Print ISBN: 978-1-61779-411-7

  • Online ISBN: 978-1-61779-412-4

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