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Stimuli Responsive Polymers for Nanoengineering of Biointerfaces

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Nanotechnology in Regenerative Medicine

Part of the book series: Methods in Molecular Biology ((MIMB,volume 811))

Abstract

There is an increasing demand on the development of “smart” switchable interfaces since controlling surface topography and chemical functionality on a nanometer scale is crucial for numerous biomedical applications. Those surfaces, which are based on stimuli responsive polymers (SRPs), are able to modify their interactions with cells, biomolecules responding to different physical (e.g., temperature) or chemical (e.g., pH) stimuli. Such behavior may partially mimic complex dynamic properties of natural systems that are regulated by many biological stimuli. This paper reviews major studies and applications of SRPs as biointerfaces in a form of thin polymeric films (gels) and surface tethered polymers (brushes).

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Acknowledgments

The author acknowledges the financial support from the project operated within the Foundation for Polish Science Team Programme cofinanced by the EU European Regional Development Fund, PolyMed, TEAM/2008-2/6. Dr. Edmondo M. Benetti (ETH Zürich) is kindly acknowledged for his comments to the protocol part.

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  1. Faculty of Chemistry, Jagiellonian University, Krakow, Poland

    Szczepan Zapotoczny

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  1. Szczepan Zapotoczny
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Correspondence to Szczepan Zapotoczny .

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  1. (IBEC), Inst. for Bioengineering of Catalonia, C/Baldiri Reixac 10-12, Barcelona, 08028, Spain

    Melba Navarro

  2. (IBEC), Inst. for Bioengineering of Catalonia, C/Baldiri Reixac 10-12, Barcelona, 08028, Spain

    Josep A. Planell

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Zapotoczny, S. (2012). Stimuli Responsive Polymers for Nanoengineering of Biointerfaces. In: Navarro, M., Planell, J. (eds) Nanotechnology in Regenerative Medicine. Methods in Molecular Biology, vol 811. Humana Press. https://doi.org/10.1007/978-1-61779-388-2_4

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  • DOI: https://doi.org/10.1007/978-1-61779-388-2_4

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  • Print ISBN: 978-1-61779-387-5

  • Online ISBN: 978-1-61779-388-2

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